Angel Room (Afterbirth Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
DLC Indicator.png Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
DLC Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Afterbirth† Indicator.png Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Afterbirth† Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Items in this pool can be found in the Angel Room.

Activated Collectibles

Name Icon Description Recharge
Breath of Life Breath of Life Icon.pngGrants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage.6 seconds
Dead Sea Scrolls Dead Sea Scrolls Icon.pngTriggers the effect of a random activated item from a list of possible options (not every activated item is included).2
Prayer Card Prayer Card Icon.pngGrants an Eternal Heart per use.6
The Bible The Bible Icon.pngUpon activation, Isaac gains Flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.6

Passive Collectibles

Name Icon Description
Celtic Cross Celtic Cross Icon.pngGrants a chance to trigger the Book Of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Censer Censer Icon.pngGives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies inside it.
Circle Of Protection Circle Of Protection Icon.pngGives Isaac a large white halo around him, that deals a bit of damage to any enemies in contact with the ring. Every time an enemy bullet enters the ring, there is a chance it will reflect a homing tear back at the enemy.
Crown Of Light Crown Of Light Icon.pngGives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
Dead Dove Dead Dove Icon.pngGrants spectral tears and flight.
Godhead Godhead Icon.pngIncreases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
Guardian Angel Guardian Angel Icon.pngSpawns an orbital familiar that blocks enemy projectiles, deals contact damage to enemies and increases the speed of all orbital familiars.
Habit Habit Icon.pngWhen Isaac is hit, 1 point of an item's charge is filled.
Holy Grail Holy Grail Icon.pngGrants flight and one heart container.
Holy Light! Holy Light! Icon.pngIsaac has a random chance to fire a Holy tear, which when it hits an enemy, will spawn a Crack The Sky style light beam on the same enemy, dealing damage.
Holy Mantle Holy Mantle Icon.pngAutomatically negates first taken damage in every room.
Holy Water Holy Water Icon.pngWhen Isaac receives damage, the bottle breaks and a puddle of blue Creep forms, which damages non-flying enemies, similar to Lemon Mishap. The bottle is reformed upon entering a different room.
Immaculate Conception Immaculate Conception Icon.pngUpon picking up a certain amount of health, spawn a permanent angelic familiar.
Lazarus' Rags Lazarus' Rags Icon.pngUpon dying, resurrect as Revived Lazarus with one heart container and Anemic item.
Mitre Mitre Icon.pngGrants a chance of converting any red hearts pickups into soul hearts instead.
Rosary Rosary Icon.pngAdds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.
Sacred Heart Sacred Heart Icon.pngIncreases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
Scapular Scapular Icon.pngOnce per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.
Seraphim Seraphim Icon.pngAn angel familiar which follows Isaac and fires homing tears which deal 10 damage at -25% shot speed and a reduced fire rate.
Spear Of Destiny Spear Of Destiny Icon.pngIn addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts Fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.
Sworn Protector Sworn Protector Icon.pngAn orbital angel which does 7 contact damage per tick and blocks enemy shots. When it blocks a shot, it has a very small chance to drop an eternal heart.
The Body The Body Icon.pngAdds 3 Heart Containers.
The Halo The Halo Icon.pngGrants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
The Mind The Mind Icon.pngGrants the combined effects of the Blue Map, Treasure Map and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.
The Relic The Relic Icon.pngIsaac is followed by a small blue cross that will drop a Soul Heart every 4 rooms.
The Soul The Soul Icon.pngGrants two Soul Hearts. Isaac now repels enemy projectiles.
The Wafer The Wafer Icon.pngAll sources of damage that would cause more than one half heart of damage are reduced to one half heart instead.
Trinity Shield Trinity Shield Icon.pngIsaac gains a shield that protects him from enemy shots.