Boss (Afterbirth Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
DLC Indicator.png Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
DLC Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Afterbirth† Indicator.png Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Afterbirth† Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

The Boss Pool is the pool of items that are dropped by bosses and can be found in the Boss Challenge Room.

Name Icon Description
<3 Less Than Three Icon.pngIncreases available heart containers by 1 and restores all health.
A Snack A Snack Icon.pngAdds 1 Heart Container.
Binky Binky Icon.pngTears up, adds 1 soul heart, and decreases Isaac's size.
Blood Clot Blood Clot Icon.pngIncreases damage by 1 and range by 5 for tears fired from the left eye.
Blue Cap Blue Cap Icon.pngGrants 1 heart container and increases tears, but decreases shot speed.
Box Box Icon.pngSpawns 1 of each (non-collectible) item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.
Breakfast Breakfast Icon.pngAdds 1 Heart Container.
Caffeine Pill Caffeine Pill Icon.pngIncreases speed and reduces character size. Also gives a random pill.
Cat-O-Nine-Tails Cat-O-Nine-Tails Icon.pngIncreases Shot Speed and damage.
Crack Jacks Crack Jacks Icon.pngAdds one heart container and drops a random Trinket.
Dessert Dessert Icon.pngAdds 1 Heart Container.
Dinner Dinner Icon.pngAdds 1 Heart Container.
Experimental Treatment Experimental Treatment Icon.pngRandomly increases and decreases some of the character's stats. There will always be at least one stat increase and one decrease and the same stats can be increased/decreased multiple times.
Growth Hormones Growth Hormones Icon.pngIncreases damage by 1 and speed by 0.4.
Jesus Juice Jesus Juice Icon.pngIncreases Damage and Range.
Latch Key Latch Key Icon.pngIncreases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Little Steven Little Steven Icon.pngSpawns a familiar that follows Isaac around and fires homing tears.
Lunch Lunch Icon.pngAdds 1 Heart Container.
MEAT! MEAT! Icon.pngAdds a heart container, and increases damage.
Magic 8 Ball Magic 8 Ball Icon.pngIncreases Shot Speed, and drops a Tarot Card when picked up.
Magic Mushroom Magic Mushroom Icon.pngIncreases all stats and enlargens Isaac
Magic Scab Magic Scab Icon.pngIncreases luck and HP by 1.
Match Book Match Book Icon.pngGrants Isaac 1 Black Heart and 3 bombs. Can also give troll bombs.
Mom's Coin Purse Mom's Coin Purse Icon.pngSpawns 4 random Pills around Isaac.
Mom's Heels Mom's Heels Icon.pngIncreases range.
Mom's Lipstick Mom's Lipstick Icon.pngIncreases range and shot height.
Mom's Pearls Mom's Pearls Icon.png+1.25 Range Up. +0.5 Tear Height. +1 Luck Up.
Mom's Underwear Mom's Underwear Icon.pngIncreases range.
Mr. Dolly Mr. Dolly Icon.pngTears and Range up. Spawns 3 random types of hearts on the floor when picked up
Old Bandage Old Bandage Icon.pngAdds one empty heart container. Whenever Isaac takes damage there's a chance that a Red Heart may drop.
PJs PJs Icon.pngAdds 4 Soul Hearts and fully restores Isaac's red health.
Pageant Boy Pageant Boy Icon.pngSpawns several coins around Isaac.
Pentagram Pentagram Icon.pngIncreases Damage and increases chances of the Devil Room appearing.
Placenta Placenta Icon.pngGrants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Roid Rage Roid Rage Icon.pngIncreases speed by 0.6, range by 5.25, and tear height by 0.5.
Rotten Meat Rotten Meat Icon.pngAdds one heart container.
Safety Pin Safety Pin Icon.pngIncreases range and shot speed, while adding 1 Black Heart.
Screw Screw Icon.pngTears and shot speed up.
Speed Ball Speed Ball Icon.pngIncreases speed by 0.3 and shot speed by 20%.
Squeezy Squeezy Icon.pngIncreases tears by 0.4, and spawns 2 Soul Hearts pickups.
Stem Cells Stem Cells Icon.pngAdds one filled Heart Container and increases Shot Speed.
Super Bandage Super Bandage Icon.pngGrants one Heart Container and gives 2 Soul Hearts.
Synthoil Synthoil Icon.pngIncreases damage by 1, range by 5.25, and tear height by 0.5.
The Belt The Belt Icon.pngIncreases speed by 0.3.
The Halo The Halo Icon.pngGrants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
Toothpicks Toothpicks Icon.pngIncreases tears and shot speed.
Torn Photo Torn Photo Icon.pngTears + Shot speed up.
Wire Coat Hanger Wire Coat Hanger Icon.pngIncreases Tears by 0.7.
Wooden Spoon Wooden Spoon Icon.pngIncreases speed by 0.3.