Monsters refers to the many antagonistic creatures the player will encounter throughout the game.

Most monsters (with few exceptions) will damage Isaac by either touching him or shooting him with projectiles. Less frequently, monsters will spawn additional, lesser monsters, spread creep, or attempt to affect the player's movement. Along with the more common variety of monsters, champion versions can be found lurking about. These monsters are often like their common counterparts, but have a color tint or size change and drop basic pickups on death. There are also champion versions of most bosses.

There are 167 monsters in total. 35 of them were added in Afterbirth.

Monster List

Template:Black FlyTemplate:Attack FlyTemplate:Ring FlyTemplate:Dart FlyTemplate:Swarm FlyTemplate:Hush FlyTemplate:MoterTemplate:Eternal FlyTemplate:PooterTemplate:Fat FlyTemplate:Boom FlyTemplate:Red Boom FlyTemplate:Drowned Boom FlyTemplate:Level 2 FlyTemplate:Full FlyTemplate:SuckerTemplate:SpitTemplate:DipTemplate:Corn DipTemplate:SquirtTemplate:Dank SquirtTemplate:DingaTemplate:SpiderTemplate:Big SpiderTemplate:TriteTemplate:RaglingTemplate:Blister (enemy)Template:Level 2 SpiderTemplate:Ticking SpiderTemplate:Baby Long LegsTemplate:Small Baby Long LegsTemplate:Crazy Long LegsTemplate:Small Crazy Long LegsTemplate:Wall CreepTemplate:Blind CreepTemplate:Rage CreepTemplate:The ThingTemplate:BoilTemplate:GutTemplate:SackTemplate:Blue BoilTemplate:Walking BoilTemplate:Walking GutTemplate:Walking SackTemplate:Round WormTemplate:NightcrawlerTemplate:RoundyTemplate:UlcerTemplate:MulliganTemplate:MulligoonTemplate:MulliboomTemplate:HiveTemplate:NestTemplate:Drowned HiveTemplate:SwarmerTemplate:DukieTemplate:HopperTemplate:Flaming HopperTemplate:LeaperTemplate:MinistroTemplate:PacerTemplate:GusherTemplate:Black Globin's BodyTemplate:GaperTemplate:Frowning GaperTemplate:Flaming GaperTemplate:CyclopiaTemplate:Blue GaperTemplate:Greed GaperTemplate:GurgleTemplate:SplasherTemplate:SkinnyTemplate:RottyTemplate:Mr. MawTemplate:HorfTemplate:Psychic HorfTemplate:MawTemplate:Red MawTemplate:Psychic MawTemplate:BonyTemplate:Black BonyTemplate:Death's HeadTemplate:Dank Death's HeadTemplate:Flesh Death's HeadTemplate:One ToothTemplate:Fat BatTemplate:Lil' Haunt (Enemy)Template:WizoobTemplate:Red GhostTemplate:FattyTemplate:Flaming FattyTemplate:StoneyTemplate:Conjoined FattyTemplate:Blue Conjoined FattyTemplate:Pale FattyTemplate:Fat SackTemplate:BlubberTemplate:Half SackTemplate:GlobinTemplate:Gazing GlobinTemplate:Dank GlobinTemplate:Black GlobinTemplate:KnightTemplate:Selfless KnightTemplate:Floating KnightTemplate:Bone KnightTemplate:Mask + HeartTemplate:ClottyTemplate:ClotTemplate:I. BlobTemplate:Mega ClottyTemplate:Mom's HandTemplate:Mom's Dead HandTemplate:MaggotTemplate:ChargerTemplate:Drowned ChargerTemplate:SpittyTemplate:Conjoined SpittyTemplate:TumorTemplate:Psy TumorTemplate:Camillo Jr.Template:BrainTemplate:Poison MindTemplate:MemBrainTemplate:GutsTemplate:Scarred GutsTemplate:Mama GutsTemplate:ButtlickerTemplate:GrubTemplate:Para-BiteTemplate:Scarred Para-BiteTemplate:Cod WormTemplate:FredTemplate:LumpTemplate:Leech (Enemy)Template:Kamikaze LeechTemplate:Holy LeechTemplate:HostTemplate:Red HostTemplate:Walking HostTemplate:Walking Red HostTemplate:MushroomTemplate:MeatballTemplate:Nerve EndingTemplate:Nerve Ending 2Template:VisTemplate:Double VisTemplate:Scarred Double VisTemplate:ChubberTemplate:Wall HuggerTemplate:SlideTemplate:PokyTemplate:EyeTemplate:Bloodshot EyeTemplate:DopleTemplate:Evil TwinTemplate:EmbryoTemplate:BabyTemplate:Angelic BabyTemplate:ImpTemplate:HomunculusTemplate:BegottenTemplate:NullTemplate:SwingerTemplate:KeeperTemplate:HangerTemplate:Stone GrimaceTemplate:Vomit GrimaceTemplate:Gaping MawTemplate:Turret GrimaceTemplate:Stone EyeTemplate:Brimstone GrimaceTemplate:OobTemplate:Black MawTemplate:Portal

Monster	Description

Champions

Some monsters can spawn as a Champion which deviates in coloration and size from its more common form. The champion's coloration denotes which peculiar behaviors and traits it will exhibit. Champions will generally drop a pickup (coinciding with the color of the champion) when killed on normal difficulty. However, in hard mode, fewer champions will drop pickups on death. All champions will deal contact damage, regardless of what monster they are (e.g. a common Mulligan will not deal contact damage, but champion versions will). Some champions inflict full heart damage regardless of chapter. The likelihood of champions appearing is increased by unlocking the Everything Is Terrible! achievement, by carrying the Purple Heart trinket, by picking up the Champion Belt item, or by playing in hard mode. Champions are generally regarded as more dangerous than common monsters.

The identifying scheme for champion qualities is as follows:

Champion Types

Monster Variants

These uncommon variants may replace common enemies in a room.

Rebirth

Appearance	Effect	Drop
Black	Fades in and out of visibility, like a Null	Red Chest
Solid White	Invincible until all other enemies are killed.	Eternal Heart
Transparent White	Tears become spectral tears, and it can move past environmental obstacles (such as pits) that it otherwise couldn't when forced.	Golden Chest
Green	Leaves green creep as it walks.	Pill
Dark Teal	Explodes when killed.	Bomb
Gray	Has 2/3 health, but deals double damage.	Key
Orange	Attacks cause you to drop coins (like Greed or a Hanger).	Coin
Purple	Pulls Isaac toward it, like a Gaping Maw.	random Trinket
Red	×2.5 amount of HP.	Heart
Dark Red	Collapses into a flesh pile upon death and regenerates if not finished off (like a Globin).	1+1 Free Heart
Yellow	Increased movement and shot speed.	Battery
Light Blue	Releases blood shots in 8 directions when killed.	1/2 heart
Dark Blue	None.	3 Blue Flies
Pink	Periodically shoots short-ranged blood shots, similar to Gushers.	Nothing
Template:Afterbirth Pulsing Green	Splits into two copies of itself upon death.	2 normal versions of itself
Template:Afterbirth Large	Increased health, decreased speed. Larger and easier to hit. Deals double damage.	One makes you larger Pill
Template:Afterbirth Tiny	Decreased health, increased speed. Smaller and more difficult to hit.	One makes you small Pill
Template:Afterbirth Holy	Has 1-2 eternal flies circling it. Spawns another fly upon death.	Attack Fly
Template:Afterbirth Camouflage	The enemy blends into the background and briefly becomes visible when damaged.	Rune
Template:Afterbirth Pulsing Black	Repels Isaac's shots when it pulses.	Heart
Template:Afterbirth+ Crown	Increased health of the enemy by significant amount. (not other specified yet)	Various pickups.
Template:Afterbirth+ Dark Green	Appears to be extremely rare. Unknown effect	Unknown
Template:Afterbirth+ Skull	Produces a Necronomicon effect upon death.	Unknown
Template:Afterbirth+ Pulsating	Spawns an Attack Fly per hit.	Unknown
Template:Afterbirth+ Pulsing Red	Unknown	Unknown