Binding of Isaac: Rebirth Wiki
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Pokey Mans is Challenge #33. You start with Collectible Friendly Ball iconFriendly Ball and Collectible Mom's Eyeshadow iconMom's Eyeshadow with the objective being to kill Isaac (Boss).

Difficulty

Some spawns from the Collectible Friendly Ball iconFriendly Ball can cause unavoidable damage in certain rooms. Hazards or enemies can be hidden by larger allies or if many are in a group.

Strategy

  • The Collectible Friendly Ball iconFriendly Ball works differently in this challenge, summoning a random charmed enemy with each use, without the need to catch any.
  • As soon as a charmed friend dies, the Collectible Friendly Ball iconFriendly Ball instantly recharges and should be used multiple times per room.
  • Any monster designed to spawn monsters will have the spawned monster friendly towards Isaac and count towards recharging the Collectible Friendly Ball iconFriendly Ball. Example: The spider nub spawns friendly spiders.
    • However, monsters that explode into other monsters will not have their replacements friendly.
    • Some monsters will die as soon as they are spawned, leaving behind unfriendly replacements.
  • The Roundy familiar (the fat worm that breaks through the ground and shoots Collectible Ipecac iconIpecac tears) is incredibly useful as you can use it to break objects and gain access to secret rooms.
  • Do not leave a room before the Collectible Friendly Ball iconFriendly Ball has spawned its monster. Your charges will be consumed and no monster will die to replenish the charges. You will have to gain charges the old fashioned way.
  • While your own bombs won't damage the spawned monster, certain items (like Collectible Contagion iconContagion) will.
  • A charmed Vis is very useful, as its Collectible Brimstone iconBrimstone beam does enormous damage, and can be helpful with bosses.
  • Since the spiked floor in a sacrifice room can hurt flying enemies, they can be used to cycle through the less useful monsters received from the ball.
    • However, sacrifice rooms can also be very dangerous, as monsters can kill themselves on the spikes faster than they can be replaced.
  • Collectible Spear Of Destiny iconSpear Of Destiny is not recommended, as it will also kill the charmed monsters spawned from the Collectible Friendly Ball iconFriendly Ball.

{{Bug| If multiple golden flies have spawned, exiting and rejoining the game will triple or quadruple the amount of golden flies. Though doesn't seem to damage any enemies.

Reward

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Trivia

  • The title of the challenge is a play on the word Pokémon.

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