???'s Only Friend

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Item icon
Item altar
  
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5.100.320
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Added in Afterbirth(page 3, column 15, row 4)
Removed in Afterbirth(page 4, column 5, row 2)
  

???'s Only Friend Complete the Boss Rush as ???

???'s Only Friend is an unlockable passive item.

Effects[edit | edit source]

  • Gives Isaac a controllable familiar that damages enemies on touch. It can be moved using the shooting directional keys, similarly to The Ludovico Technique The Ludovico Technique and Robo-Baby 2.0 Robo-Baby 2.0.
    • ???'s Only Friend deals 2.5 damage per tick, and ticks 15 times a second, dealing a total of 37.5 damage per second.
  • This item belongs to the Beelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.

Notes[edit | edit source]

  • Unlike The Ludovico Technique, it cannot be controlled with the mouse, even with mouse control enabled.
  • Holding two opposite fire keys (both left and right or both up and down) at the same time will keep the familiar in place, while making Isaac fire in the direction of whichever fire key was pressed second.
    • This can help during combats with bosses who do not move a lot, as the familiar can continuously damage the boss when kept stationary.
    • On some keyboards, holding opposite fire keys may cause other keys to become unresponsive.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

PC Normal mode only HC7F QZAT (Treasure Room adjacent to spawn)

PC Normal mode only J6S4 VMQM (Treasure Room adjacent to spawn)

PC Hard mode only 6CQZ CL2Y (Treasure Room adjacent to spawn)

PC Added in Afterbirth † Normal and hard modes only 0CN2 GSH1 (Treasure Room adjacent to spawn)

PS4 Y4FW NYCX (First floor treasure room)

Switch Greed mode only 6RS1 FT1H (First Golden Treasure Room)


Fly Items
??? (Character) Unlocks ??? (Character) Unlocks ??? (Character) Unlocks
The D6Forget Me Now???'s SoulFate???'s Only FriendDead Baby Fate's RewardCracked DiceBlue BabyHive Baby King BabyMeconium
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets
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