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???'s Only Friend is an unlockable passive item.

Effects[ | ]

  • Spawns a controllable familiar that damages enemies on touch. It can be moved using the shooting directional keys, similarly to Collectible The Ludovico Technique iconThe Ludovico Technique and Collectible Robo-Baby 2.0 iconRobo-Baby 2.0.
    • (except in Repentance) ???'s Only Friend deals 2.5 damage per tick, and ticks 15 times a second, dealing a total of 37.5 damage per second.
      • (in Repentance) ???'s Only Friend deals 3.5 damage per tick, and ticks ~4.3 times per second, dealing a total of 15 damage per second.
  • This item belongs to the BeelzebubBeelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.

Notes[ | ]

  • Unlike The Ludovico Technique, it cannot be controlled with the mouse, even with mouse control enabled.
  • Holding two opposite fire keys (both left and right or both up and down) at the same time will keep the familiar in place, while making Isaac fire in the direction of whichever fire key was pressed second.
    • This can help during combats with bosses who do not move a lot, as the familiar can continuously damage the boss when kept stationary.
    • On some keyboards, holding opposite fire keys may cause other keys to become unresponsive.

In-game Footage[ | ]

Gallery[ | ]

Trivia[ | ]

  • The sprite for the familiar resembles a Boom FlyBoom Fly, which has been resprited to fit the blue/dead nature of ??? and Hush, similar to the (except in Rebirth) Hush FlyHush Fly, (except in Rebirth) Blue GaperBlue Gaper, and (except in Rebirth)Collectible Fate's Reward iconFate's Reward
  • This item is slightly faster than Robo-Baby 2.0, but is only noticeable when rapid clicking the tear button.


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