Achievements

For tips and strategies on completing achievements, see Achievement Tips.

Achievements are unlocked for players after completing challenges, reaching certain milestones, achieving hidden goals, or unlocking certain items. In the PC version, every Steam achievement exactly corresponds to one secret in-game, whereas only a handful of secrets are represented by PSN trophies in the Playstation version of the game. If you are unable to unlock achievements, a small icon of a crossed-out trophy is displayed.

All Achievements

Name	Image	Description	Unlock	In Game Secret Number	Platforms
Magdalene		Unlocked a new character.	Have 7 or more heart containers at one time	1	All
Cain		Unlocked a new character.	Hold 55 coins at one time	2	All
Judas		Unlocked a new character.	Defeat Satan for the 1st time	3	All
The Womb		Chapter 4 - The Womb unlocked.	Defeat Mom for the 1st time	4	All
The Harbingers		The horsemen are loose.	Defeat Mom for the 1st time	5	All
A Cube of Meat		Unlocked a new item. (Also unlocks the Ball of Bandages)	Defeat Mom for the 1st time	6	All
The Book of Revelations		Unlocked a new item.	Defeat a Harbinger for the 1st time	7	All
A Noose		Unlocked a new item.	Defeat Mom's Heart 3 times	8	All
The Nail		Unlocked a new item.	Complete the Boss Rush as Azazel	9	All
A Quarter		Unlocked a new item.	Defeat Mom's Heart 8 times	10	All
A Fetus in a Jar		Unlocked a new item.	Defeat Mom's Heart 9 times	11	All
A Small Rock		Unlocked a new item.	Destroy 100 tinted rocks	12	All
Monstro's Tooth		Unlocked a new item.	Beat chapter 1 for the 1st time	13	All
Lil' Chubby		Unlocked a new item.	Beat Chapter 2 for the 1st time	14	All
Loki's Horns		Unlocked a new item.	Defeat Lokii for the 1st time	15	All
Something From The Future		New boss in the basement!	Beat The Basement 40 times	16	All
Something Cute		New boss in the caves!	Beat Chapter 2 30 times	17	All
Something Sticky		New boss in the depths!	Beat Chapter 3 20 times	18	All
A Bandage		Unlocked a new item.	Make a Super Bandage Girl by picking up 4 Balls of Bandages in one run; see unlocking Super Meat Boy & Super Bandage Girl	19	All
A Cross		Unlocked a new item.	Defeat Isaac as Magdalene	20	All
A Bag of Pennies		Unlocked a new item.	Defeat Isaac as Cain	21	All
The Book of Sin		Unlocked a new item.	Defeat all 7 deadly sins	22	All
Little Gish		Unlocked a new item.	Defeat Gish for the 1st time	23	All
Little Steven		Unlocked a new item.	Defeat Steven for the 1st time	24	All
Little C.H.A.D.		Unlocked a new item.	Defeat C.H.A.D. for the 1st time	25	All
A Gamekid		Unlocked a new item.	Visit 10 arcades	26	All
A Halo		Unlocked a new item.	Defeat Mom using The Bible	27	All
Mr. Mega		Unlocked a new item.	Destroy 10 tinted rocks	28	All
The D6		Isaac now holds the D6!	Defeat Isaac as ???	29	All
The Scissors		Unlocked a new item.	Die 100 times	30	All
The Parasite		Unlocked a new item.	Pick up any 2 of the following items in a single run: Bob's Rotten Head, Dead Cat, Cricket's Head, Tammy's Head	31	All
???		Unlocked a new character.	Defeat Mom's Heart 10 times	32	All
Everything Is Terrible!!!		The game just got harder!	Defeat Mom's Heart 5 times	33	All
It Lives!		Your future's past waits.	Defeat Mom's Heart 11 times	34	All
Mom's Contact		Unlocked a new item.	Obtain three Mom items in one run	35	All
The Necronomicon		Unlocked a new item.	Use XIII - Death 4 times	36	All
Basement Boy		Beat basement without taking damage.	Beat chapter 1 without taking damage	37	All
Spelunker Boy		Beat caves without taking damage.	Beat chapter 2 without taking damage	38	All
Dark Boy		Beat depths without taking damage.	Beat chapter 3 without taking damage	39	All
Mama's Boy		Beat womb without taking damage.	Beat chapter 4 without taking damage	40	All
Golden God!		You are the best!!	Defeat ??? and The Lamb for the 1st time	41	All
Eve		Unlocked a new character.	Don't pick up any hearts for 2 floors in a row	42	All
Mom's Knife		Unlocked a new item.	Defeat Satan as Isaac	43	All
The Razor		Unlocked a new item.	Defeat Satan as Eve	44	All
Guardian Angel		Unlocked a new item.	Defeat Satan as Magdalene	45	All
A Bag of Bombs		Unlocked a new item.	Defeat Satan as Cain	46	All
Demon Baby		Unlocked a new item.	Defeat The Lamb as Azazel	47	All
Forget Me Now		Unlocked a new item.	Defeat Satan as ???	48	All
The D20		Unlocked a new item.	Defeat ??? as Isaac	49	All
Celtic Cross		Unlocked a new item.	Defeat ??? as Magdalene	50	All
Abel		Unlocked a new item.	Defeat The Lamb as Cain	51	All
Curved Horn		Unlocked a new item.	Defeat The Lamb as Judas	52	All
Sacrificial Dagger		Unlocked a new item.	Defeat ??? as Eve	53	All
Bloody Lust		Unlocked a new item.	Defeat Isaac as Samson	54	All
Blood Penny		Unlocked a new item.	Defeat ??? as Samson	55	All
Blood Rights		Unlocked a new item.	Defeat Satan as Samson	56	All
The Polaroid		Unlocked a new item.	Defeat Isaac 5 times	57	All
Dad's Key		Unlocked a new item.	Pick up both Key Pieces from the Angels in one run	58	All
Blue Candle		Unlocked a new item.	Donate 900 coins to the Donation Machine	59	All
Burnt Penny		Unlocked a new item.	Complete challenge #13	60	All
Lucky Toe		Unlocked a new item.	Blow up 20 shopkeepers	61	All
Epic Fetus		Unlocked a new item.	Complete challenge #19	62	All
SMB Super Fan		Unlocked a new item.	Complete challenge #14	63	All
Counterfeit Coin		Unlocked a new item.	Play the shell game 100 times	64	All
Guppy's Hairball		Unlocked a new item.	Become Guppy	65	All
A Forgotten Horseman		Unlocked a new boss!	Take 10 items from Angel rooms	66	All
Samson		Unlocked a new character.	Complete 2 floors in a row without taking damage	67	All
Something Icky		New boss in the womb!	Defeat Isaac 10 times	68	All
!Platinum God!		OMG!	Collect all items in the game, unlock all of the secrets and endings minus The Lost and his 6 unlockable items	69	All
Isaac's Head		Unlocked a new item.	Complete the Boss Rush as Isaac	70	All
Maggy's Faith		Unlocked a new item.	Defeat The Lamb as Magdalene	71	All
Judas' Tongue		Unlocked a new item.	Defeat Satan as Judas	72	All
???'s Soul		Unlocked a new item.	Defeat The Lamb as ???	73	All
Samson's Lock		Unlocked a new item.	Defeat The Lamb as Samson	74	All
Cain's Eye		Unlocked a new item.	Defeat ??? as Cain	75	All
Eve's Bird Foot		Unlocked a new item.	Defeat Isaac as Eve	76	All
The Left Hand		Unlocked a new item.	Defeat Ultra Pride or ??? as Judas	77	All
The Negative		Unlocked a new item.	Defeat Satan 5 times	78	All
Azazel		Unlocked a new character.	Make 3 deals with the devil in one run	79	All
Lazarus		Unlocked a new character.	Have 4 or more soul hearts at one time	80	All
Eden		Unlocked a new character.	Complete chapter 4 for the 1st time	81	All
The Lost		Unlocked a new character.	It's complicated Die in a Sacrifice Room while holding Missing Poster	82	All
Dead Boy		Beat Chest or Dark Room without taking damage.	Complete chapter 6 without taking damage	83	All
The Real Platinum God		111% now stop playing!	Collect every item and unlock every ending.	84	All
Lucky Rock		Destroy 100 rocks.	Destroy 100 rocks	85	All
The Cellar		Alt stage to the basement.	Beat all The Basement bosses (not restricted to beating bosses in the Basement)	86	All
The Catacombs		Alt stage to the caves.	Beat all The Caves bosses (not restricted to beating bosses in the Caves)	87	All
The Necropolis		Alt stage to the depths.	Beat all The Depths bosses (not restricted to beating bosses in the Depths)	88	All
Rune of Hagalaz		Unlocked a new item.	Complete challenge #1	89	All
Rune of Jera		Unlocked a new item.	Complete challenge #2	90	All
Rune of Ehwaz		Unlocked a new item.	Complete challenge #3	91	All
Rune of Dagaz		Unlocked a new item.	Complete challenge #4	92	All
Rune of Ansuz		Unlocked a new item.	Complete challenge #5	93	All
Rune of Perthro		Unlocked a new item.	Complete challenge #6	94	All
Rune of Berkano		Unlocked a new item.	Complete challenge #20	95	All
Rune of Algiz		Unlocked a new item.	Complete challenge #8	96	All
Chaos Card		Unlocked a new item.	Complete challenge #9	97	All
Credit Card		Unlocked a new item.	Complete challenge #10	98	All
Rules Card		Unlocked a new item.	Complete challenge #11	99	All
Card Against Humanity		Unlocked a new item.	Complete challenge #12	100	All
Swallowed Penny		Unlocked a new item.	Complete challenge #15	101	All
Robo-Baby 2.0		Unlocked a new item.	Complete challenge #16	102	All
Death's Touch		Unlocked a new item.	Complete challenge #17	103	All
Technology .5		Unlocked a new item.	Complete challenge #18	104	All
Missing No.		Unlocked a new item.	Complete the Boss Rush as Lazarus	105	All
Isaac's Tears		Unlocked a new item.	Defeat Isaac as Isaac	106	All
Guillotine		Unlocked a new item.	Defeat Isaac as Judas	107	All
Judas' Shadow		Unlocked a new item.	Complete the Boss Rush as Judas	108	All
Maggy's Bow		Unlocked a new item.	Complete the Boss Rush as Magdalene	109	All
Cain's Other Eye		Unlocked a new item.	Complete the Boss Rush as Cain	110	All
Black Lipstick		Unlocked a new item.	Defeat The Lamb as Eve	111	All
Eve's Mascara		Unlocked a new item.	Complete the Boss Rush as Eve	112	All
Fate		Unlocked a new item.	Defeat ??? as ???	113	All
???'s Only Friend		Unlocked a new item.	Complete the Boss Rush as ???	114	All
Samson's Chains		Unlocked a new item.	Complete the Boss Rush as Samson	115	All
Lazarus' Rags		Unlocked a new item.	Defeat Isaac as Lazarus	116	All
Broken Ankh		Unlocked a new item.	Defeat Satan as Lazarus	117	All
Store Credit		Unlocked a new item.	Defeat ??? as Lazarus	118	All
Pandora's Box		Unlocked a new item.	Defeat The Lamb as Lazarus	119	All
Suicide King		Unlocked a new item.	Complete challenge #7	120	All
Blank Card		Unlocked a new item.	Defeat Isaac as Eden	121	All
Book of Secrets		Unlocked a new item.	Defeat Satan as Eden	122	All
Mysterious Paper		Unlocked a new item.	Beat ??? as Eden	123	All
Mystery Sack		Unlocked a new item.	Defeat The Lamb as Eden	124	All
Undefined		Unlocked a new item.	Complete the Boss Rush as Eden	125	All
Satanic Bible		Unlocked a new item.	Defeat Isaac as Azazel	126	All
Daemon's Tail		Unlocked a new item.	Defeat Satan as Azazel	127	All
Abaddon		Unlocked a new item.	Defeat ??? as Azazel	128	All
Isaac's Heart		Unlocked a new item.	Defeat Isaac as The Lost	129	All
The Mind		Unlocked a new item.	Defeat Satan as The Lost	130	All
The Body		Unlocked a new item.	Defeat ??? as The Lost	131	All
The Soul		Unlocked a new item.	Defeat The Lamb as The Lost	132	All
The D100		Unlocked a new item.	Complete the Boss Rush as The Lost	133	All
Blue Map		Unlocked a new item.	Donate 10 coins to the Donation Machine	134	All
There's Options		Unlocked a new item.	Donate 50 coins to the Donation Machine	135	All
Black Candle		Unlocked a new item	Donate 150 coins to the Donation Machine	136	All
Red Candle		Unlocked a new item.	Donate 400 coins to the Donation Machine	137	All
Stop Watch		Unlocked a new item	Donate 999 coins to the Donation Machine	138	All
Wire Coat Hanger		Unlocked a new item.	Defeat Mom's Heart 4 times	139	All
Ipecac		Unlocked a new item.	Defeat Mom's Heart 6 times	140	All
Experimental Treatment		Unlocked a new item.	Defeat Mom's Heart 7 times	141	All
Krampus		Unlocked another miniboss!	Take 20 items from devil rooms	142	All
Head of Krampus		Unlocked a new item.	Defeat Krampus for the 1st time	143	All
Super Meat Boy		Built him out of meat cubes.	Make a Super Meat Boy by picking up 4 Cubes of Meat in one run; see methods to create a Super Meat Boy	144	All
Butter Bean		Unlocked a new item.	Destroy 100 poops	145	All
Little Baggy		Unlocked a new item.	Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment or Speed Ball	146	All
Blood Bag		Unlocked a new item.	Use the Blood Donation Machine 30 times	147	All
The D4		Unlocked a new item.	Blow up 30 arcade machines	148	All
Missing Poster		Unlocked a new item.	Defeat The Lamb as Isaac	149	All
Rubber Cement		Unlocked a new item.	Defeat Mom's Heart 2 times	150	All
Store Upgrade lv.1		Donated 20 pennies to the shop.	Donate 20 coins to the Donation Machine	151	All
Store Upgrade lv.2		Donated 100 pennies to the shop.	Donate 100 coins to the Donation Machine	152	All
Store Upgrade lv.3		Donated 200 pennies to the shop.	Donate 200 coins to the Donation Machine	153	All
Store Upgrade lv.4		Donated 600 pennies to the shop.	Donate 600 coins to the Donation Machine	154	All
Angels		They are waiting.	Complete Chapter 6	155	All
Godhead		Unlocked a new item.	Beat Mom's Heart, Isaac, Satan, ???, and The Lamb and complete the Boss Rush on hard mode as The Lost Earn all 9 Completion Marks on hard mode as The Lost	156	All
Darkness Falls		Unlocked Challenge #4.	Defeat Mom's Heart 11 times	157	All
The Tank		Unlocked Challenge #5.	Have 7 or more heart containers at one time	158	All
Solar System		Unlocked Challenge #6.	Defeat Mom's Heart 3 times	159	All
Suicide King		Unlocked Challenge #7.	Defeat Mom's Heart 11 times	160	All
Cat Got Your Tongue		Unlocked Challenge #8.	Become Guppy (Collect 3 Guppy Items)	161	All
Demo Man		Unlocked Challenge #9.	Defeat Mom's Heart 9 times	162	All
Cursed!		Unlocked Challenge #10.	Have 7 or more heart containers at one time	163	All
Glass Cannon		Unlocked Challenge #11.	Beat challenge #19 and defeat Lokii for the 1st time	164	All
The Family Man		Unlocked Challenge #19.	Pick up both Key pieces from the Angels in one run	165	All
Purist		Unlocked Challenge #20.	Defeat Mom for the first time	166	All
Lost Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Isaac	167	All
Cute Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Magdalene	168	All
Crow Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Eve	169	All
Shadow Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Judas	170	All
Glass Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Cain	171	All
Wrapped Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Azazel Defeat Mom's Heart on hard mode as Lazarus	172	All
Begotten Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Lazarus Defeat Mom's Heart on hard mode as Azazel	173	All
Dead Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as ???	174	All
-0- Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as The Lost	175	All
Glitch Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Eden	176	All
Fighting Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Samson	177	All
Lord of the Flies		You became Lord of the Flies.	Become Lord of the Flies	178	All
Fart Baby		Unlocked a new item.	Defeat Hush as Isaac	179	All
Purity		Unlocked a new item.	Defeat Hush as Magdalene	180	All
D12		Unlocked a new item.	Defeat Hush as Cain	181	All
Betrayal		Unlocked a new item.	Defeat Hush as Judas	182	All
Fate's Reward		Unlocked a new item.	Defeat Hush as ???	183	All
Athame		Unlocked a new item.	Defeat Hush as Eve	184	All
Blind Rage		Unlocked a new item.	Defeat Hush as Samson	185	All
Maw of the Void		Unlocked a new item.	Defeat Hush as Azazel	186	All
Empty Vessel		Unlocked a new item.	Defeat Hush as Lazarus	187	All
Eden's Blessing		Unlocked a new item.	Defeat Hush as Eden	188	All
Sworn Protector		Unlocked a new item.	Defeat Hush as The Lost	189	All
Incubus		Unlocked a new item.	Defeat Hush as Lilith	190	All
Keeper now holds... A Penny!		Unlocked a new item.	Defeat Hush as Keeper	191	All
Lil' Chest		Unlocked a new item.	Defeat Ultra Greed as Isaac	192	All
Censer		Unlocked a new item.	Defeat Ultra Greed as Magdalene	193	All
Evil Eye		Unlocked a new item.	Defeat Ultra Greed as Cain	194	All
My Shadow		Unlocked a new item.	Defeat Ultra Greed as Judas	195	All
Cracked Dice		Unlocked a new item.	Defeat Ultra Greed as ???	196	All
Black Feather		Unlocked a new item.	Defeat Ultra Greed as Eve	197	All
Lusty Blood		Unlocked a new item.	Defeat Ultra Greed as Samson	198	All
Lilith		Unlocked a new character.	Defeat Ultra Greed as Azazel	199	All
Key Bum		Unlocked a new item.	Defeat Ultra Greed as Lazarus	200	All
GB Bug		Unlocked a new item.	Defeat Ultra Greed as Eden	201	All
Zodiac		Unlocked a new item.	Defeat Ultra Greed as The Lost	202	All
Box of Friends		Unlocked a new item.	Defeat Ultra Greed as Lilith	203	All
Rib of Greed		Unlocked a new item.	Defeat Ultra Greed as Keeper	204	All
Cry Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Isaac	205	All
Red Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Magdalene	206	All
Green Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Cain	207	All
Brown Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Judas	208	All
Blue Baby		Unlocked a new co-player baby.	Defeat Mega Satan as ???	209	All
Lil' Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Eve	210	All
Rage Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Samson	211	All
Black Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Azazel	212	All
Long Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Lazarus	213	All
Yellow Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Eden	214	All
White Baby		Unlocked a new co-player baby.	Defeat Mega Satan as The Lost	215	All
Big Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Lilith	216	All
Noose Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Keeper	217	All
Rune Bag		Unlocked a new item.	Defeat Isaac as Lilith	218	All
Cambion Conception		Unlocked a new item.	Defeat ??? as Lilith	219	All
Serpent's Kiss		Unlocked a new item.	Defeat Satan as Lilith	220	All
Succubus		Unlocked a new item.	Defeat The Lamb as Lilith	221	All
Immaculate Conception		Unlocked a new item.	Complete the Boss Rush as Lilith	222	All
Goat Head Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Lilith	223	All
Gold Heart		Unlocked a new item.	Complete challenge #21	224	All
Get out of Jail Free Card		Unlocked a new item.	Complete challenge #22	225	All
Gold Bomb		Unlocked a new item.	Complete challenge #23	226	All
2 new pills		Unlocked a new item.	Complete challenge #24	227	All
2 new pills		Unlocked a new item.	Complete challenge #25	228	All
Poker Chip		Unlocked a new item.	Complete challenge #26	229	All
Stud Finder		Unlocked a new item.	Complete challenge #27	230	All
D8		Unlocked a new item.	Complete challenge #28	231	All
Kidney Stone		Unlocked a new item.	Complete challenge #29 ( The unlock is bugged and actually unlocks Blank Rune)	232	All
Blank Rune		Unlocked a new item.	Complete challenge #30 ( The unlock is bugged and actually unlocks Kidney Stone)	233	All
Blue Womb		Unlocked a hidden chapter.	Defeat Mom's Heart 10 times	234	All
1001%		Nerd x 1000000	Unlock all of the secrets and endings, and collect every item in the game	235	All
Keeper holds Wooden Nickel		Unlocked a new starting item.	Defeat Isaac as Keeper	236	All
Keeper holds Store Key		Unlocked a new starting item.	Defeat Satan as Keeper	237	All
Deep Pockets		Unlocked a new item.	Defeat ??? as Keeper	238	All
Karma		Unlocked a new item.	Defeat The Lamb as Keeper	239	All
Sticky Nickels		Unlocked a new item.	Complete the Boss Rush as Keeper	240	All
Super Greed Baby		Unlocked a new co-player baby.	Defeat Mom's Heart on hard mode as Keeper	241	All
Lucky Pennies		Unlocked a new item.	Donate 1 coin to the Greed Machine	242	All
Special Hanging Shopkeepers		Unlocked a secret.	Donate 10 coins to the Greed Machine	243	All
Wooden Nickel		Unlocked a new item.	Donate 30 coins to the Greed Machine	244	All
Cain holds Paperclip		Unlocked a new starting item.	Donate 68 coins to the Greed Machine	245	All
Everything is Terrible 2!!!		Greed just got harder!	Donate 111 coins to the Greed Machine	246	All
Special Shopkeepers		Unlocked a secret.	Donate 234 coins to the Greed Machine	247	All
Eve now holds Razor Blade		Unlocked a new starting item.	Donate 439 coins to the Greed Machine	248	All
Store Key		Unlocked a new item.	Donate 666 coins to the Greed Machine	249	All
Lost holds Holy Mantle		Unlocked a new starting item.	Donate 879 coins to the Greed Machine	250	All
Keeper		Unlocked a new character.	Donate 1000 coins to the Greed Machine	251	All
Hive Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as ???	252	All
Buddy Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Isaac	253	All
Colorful Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Magdalene	254	All
Whore Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Eve	255	All
Cracked Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Eden	256	All
Dripping Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Lazarus	257	All
Blinding Baby		Unlocked a new co-player baby.	Use Blank Card while holding XIX - The Sun	258	All
Sucky Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Azazel	259	All
Dark Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Lilith	260	All
Picky Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Cain	261	All
Revenge Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Samson	262	All
Belial Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Judas	263	All
Sale Baby		Unlocked a new co-player baby.	Earn all hard mode completion marks as Keeper	264	All
XXXXXXXXL		Unlocked Challenge #21.	Defeat Mom for the 1st time	265	All
SPEED!		Unlocked Challenge #22.	Defeat Mom for the 1st time	266	All
Blue Bomber		Unlocked Challenge #23.	Destroy 10 tinted rocks and defeat Mom's Heart 11 times	267	All
PAY TO PLAY		Unlocked Challenge #24.	Defeat Isaac as Cain	268	All
Have a Heart		Unlocked Challenge #25.	Defeat Mom for the 1st time	269	All
I RULE!		Unlocked Challenge #26.	Defeat ??? or The Lamb for the 1st time, and defeat Satan as Isaac	270	All
BRAINS!		Unlocked Challenge #27.	Defeat Isaac 5 times	271	All
PRIDE DAY!		Unlocked Challenge #28.	Defeat Mom for the 1st time	272	All
Onan's Streak		Unlocked Challenge #29.	Defeat Mom for the 1st time	273	All
The Guardian		Unlocked Challenge #30.	Defeat Mom for the 1st time	274	All
Generosity		If only everyone was as generous as you are...	Donate 999 coins to the Greed Machine	275	All
Mega		Unlocked...	Defeat Mega Satan as every character	276	All
Backasswards		Unlocked a new challenge.	Defeat ??? or The Lamb for the 1st time	277	All
Aprils fool		Unlocked a new challenge.	Defeat Mom for the 1st time	278	All
Pokey Mans		Unlocked a new challenge.	Defeat Mom's Heart 11 times	279	All
Ultra Hard		Unlocked a new challenge.	Defeat ??? or The Lamb for the first time	280	All
PONG		Unlocked a new challenge.	Defeat Isaac 5 times	281	All
D Infinity		Unlocked a new item.	Defeat Delirium as Isaac	282	All
Eucharist		Unlocked a new item.	Defeat Delirium as Magdalene	283	All
Silver Dollar		Unlocked a new item.	Defeat Delirium as Cain	284	All
Shade		Unlocked a new item.	Defeat Delirium as Judas	285	All
King Baby		Unlocked a new co-player baby.	Defeat Delirium as ???	286	All
Bloody Crown		Unlocked a new item.	Defeat Delirium as Samson	287	All
Dull Razor		Unlocked a new item.	Defeat Delirium as Eve	288	All
Eden's Soul		Unlocked a new item.	Defeat Delirium as Eden	289	All
Dark Prince's Crown		Unlocked a new item.	Defeat Delirium as Azazel	290	All
Compound Fracture		Unlocked a new item.	Defeat Delirium as Lazarus	291	All
Euthanasia		Unlocked a new item.	Defeat Delirium as Lilith	292	All
Holy Card		Unlocked a new item.	Defeat Delirium as The Lost	293	All
Crooked Penny		Unlocked a new item.	Defeat Delirium as Keeper	294	All
Void		Unlocked a new item.	Defeat Delirium as Apollyon	295	All
D1		Unlocked a new item.	Defeat Ultra Greedier as Isaac	296	All
Glyph of Balance		Unlocked a new item.	Defeat Ultra Greedier as Magdalene	297	All
Sack of Sacks		Unlocked a new item.	Defeat Ultra Greedier as Cain	298	All
Eye of Belial		Unlocked a new item.	Defeat Ultra Greedier as Judas	299	All
Meconium		Unlocked a new item.	Defeat Ultra Greedier as ???	300	All
Stem Cell		Unlocked a new item.	Defeat Ultra Greedier as Samson	301	All
Crow Heart		Unlocked a new item.	Defeat Ultra Greedier as Eve	302	All
Metronome		Unlocked a new item.	Defeat Ultra Greedier as Eden	303	All
Bat Wing		Unlocked a new item.	Defeat Ultra Greedier as Azazel	304	All
Plan C		Unlocked a new item.	Defeat Ultra Greedier as Lazarus	305	All
Duality		Unlocked a new item.	Defeat Ultra Greedier as Lilith	306	All
Dad's Lost Coin		Unlocked a new item.	Defeat Ultra Greedier as The Lost	307	All
Eye of Greed		Unlocked a new item.	Defeat Ultra Greedier as Keeper	308	All
Black Rune		Unlocked a new item.	Defeat Ultra Greedier as Apollyon	309	All
Locust of War		Unlocked a new item.	Defeat Isaac as Apollyon	310	All
Locust of Pestilence		Unlocked a new item.	Defeat Satan as Apollyon	311	All
Locust of Famine		Unlocked a new item.	Defeat ??? as Apollyon	312	All
Locust of Death		Unlocked a new item.	Defeat The Lamb as Apollyon	313	All
Locust of Conquest		Unlocked a new item.	Complete the Boss Rush as Apollyon	314	All
Hushy		Unlocked a new item.	Defeat Hush as Apollyon	315	All
Brown Nugget		Unlocked a new item.	Defeat Ultra Greed as Apollyon	316	All
Mort Baby		Unlocked a new co-player baby.	Defeat Mega Satan as Apollyon	317	All
Smelter		Unlocked a new item.	Defeat Mom's Heart or It Lives! on hard mode as Apollyon	318	All
Apollyon Baby		Unlocked a new co-player baby.	Earn all Hard Mode Completion Marks as Apollyon	319	All
New Area		Unlocked a new area.	Defeat Hush for the 1st time	320	All
Once More with Feeling!		Unlocked a new item.	Complete a Victory Lap, defeating The Lamb	321	All
Hat trick!		Unlocked a new item.	Get a 3-win streak	322	All
5 Nights at Mom's		Unlocked super special rocks.	Get a 5-win streak, using a different character for each win	323	All
Sin collector		Unlocked a new item.	Collect every entry in the Bestiary (Bugged v190 - Mobs that don't exist in the bestiary are being counted. This allows Sin Collector to be unlocked without a complete bestiary)	324	All
Dedication		Unlocked a new item.	Participate in 31 Daily Challenges (they don't have to be consecutive; it will still count if you die in the first room)	325	All
ZIP!		Unlocked a new item.	Defeat The Lamb in under 20 minutes	326	All
It's the Key		Unlocked a new item.	Defeat The Lamb without taking hearts, coins, and bombs through an entire run	327	All
Mr. Resetter!		Unlocked a new item.	Reset 7 times in a row  Switch   PS4  Get a minus 10-win streak	328	All
Living on the Edge		Unlocked a new item.	Complete a floor after Basement I, start-to-finish, with only half a heart of health (can use The Lost)	329	All
U Broke It!		Unlocked a new item.	Obtain 50 items on a run (e.g., via two Steam Sales and Restock - Duplicate passives/familiars count towards the total, e.g., multiple Breakfasts)	330	All
Laz Bleeds More!		Unlocked a new starting item.	Complete challenge #31	331	All
Maggy Now Holds a Pill!		Unlocked a new starting item.	Complete challenge #32	332	All
Charged Key		Unlocked a new item.	Complete challenge #33	333	All
Samson Feels Healthy!		Unlocked a new starting item.	Complete challenge #34	334	All
Greed's Gullet		Unlocked a new item.	Complete challenge #35	335	All
The Marathon		Unlocked a new item.	Get a 5-win streak in the Daily Challenges	336	All
RERUN		Unlocked the power of RERUN.	Complete 3 Victory Laps and start a 4th	337	All
Delirious		Unlocked a new item.	Defeat Delirium for the first time as any character	338	All
1000000%		Just Stop!	Collect every item in the game, unlock all secrets and endings, and complete the Bestiary	339	All
Apollyon		Unlocked a new character.	Defeat Mega Satan for the 1st time	340	All
Greedier!		New mode unlocked!	Donate 500 coins to the Greed Machine	341	All
Burning Basement		Alt stage to the basement.	Defeat Mom's Heart 11 times	342	All
Flooded Caves		Alt stage to the caves.	Defeat It Lives 16 times	343	All
Dank Depths		Alt stage to the depths.	Defeat It Lives 21 times	344	All
Scarred Womb		Alt stage to the womb.	Defeat It Lives 30 times	345	All
Something wicked this way comes!		Unlocked new bosses!	Defeat ??? as 3 different characters	346	All
Something wicked this way comes+!		Unlocked even more bosses!	Defeat ??? as 6 different characters	347	All
The gate is open!		Unlocked new enemies!	Defeat The Lamb for the 1st time	348	All
Black Hole		Unlocked a new item.	Defeat 20 portals	349  PS4  340	All
Mystery Gift		Unlocked a new item.	Destroy 500 rocks	350  PS4  341	All
Sprinkler		Unlocked a new item.	Beat chapter 1 without taking damage	351  PS4  342	All
Angry Fly		Unlocked a new item.	Become Beelzebub	352  PS4  343	All
Bozo		Unlocked a new item.	Destroy 5 rainbow poops	353  PS4  344	All
Broken Modem		Unlocked a new item.	Complete 7 (30 on console) daily challenges (by touching the trophy at the end)	354  PS4  345	All
Buddy in a Box		Unlocked a new item.	Pick up 5 familiars in a single run	355  PS4  346	All
Fast Bombs		Unlocked a new item.	Defeat Little Horn 20 times	356  PS4  347	All
Lil Delirium		Unlocked a new item.	Defeat Delirium for the 1st time	357  PS4  348	All
Hairpin		Unlocked a new item.	Recharge using batteries 20 times	358  PS4  349	All
Wooden Cross		Unlocked a new item.	Sleep in a bed	359  PS4  350	All
Butter!		Unlocked a new item.	Complete 2 Victory Laps and start a 3rd	360  PS4  351	All
Huge Growth		Unlocked a new item.	Increase in size 5 times in a single run. Sources of increased size include "One Makes you Larger" pills, XI - Strength, and Magic Mushroom	361  PS4  352	All
Ancient Recall		Unlocked a new item.	Use cards and runes 20 times	362  PS4  353	All
Era Walk		Unlocked a new item.	Have both the Broken Watch and the Stop Watch in your collection	363  PS4  354	All
Coupon		Unlocked a new item.	Purchase from shops 50 times	364  PS4  355	All
Telekinesis		Unlocked a new item.	Beat Chapter 2 without taking damage	365  PS4  356	All
Moving Box		Unlocked a new item.	Use Pandora's Box in the Dark Room	366  PS4  357	All
Jumper Cables		Unlocked a new item.	Pick up any 3 of the following items/trinkets in a single run: 9 Volt, The Battery, Car Battery, AAA Battery, Watch Battery	367  PS4  358	All
Leprosy		Unlocked a new item.	Beat Chapter 3 without taking damage	368  PS4  359	All
Technology Zero		Unlocked a new item.	Pick up two technology items in one run	369  PS4  360	All
Filigree Feather		Unlocked a new item.	Acquire both key pieces	370  PS4  361	All
Mr. ME!		Unlocked a new item.	Open 20 locked chests	371  PS4  362	All
7 Seals		Unlocked a new item.	Defeat all 5 Harbingers	372  PS4  363	All
Angelic Prism		Unlocked a new item.	Defeat an Angel 10 times	373  PS4  364	All
Pop!		Unlocked a new item.	Beat Chapter 4 without taking damage	374  PS4  365	All
Door Stop		Unlocked a new item.	Blow up doors and secret room walls 50 times	375  PS4  366	All
Death's List		Unlocked a new item.	Take 25 devil deals	376	All
Haemolacria		Unlocked a new item.	Acquire Blood Clot 10 times	377	All
Lachryphagy		Unlocked a new item.	Collect 10 "tears up" items or pills in one run	378	All
Schoolbag		Unlocked a new item.	Enter every shop from Chapter 1 through Chapter 3 in one run	379	All
Trisagion		Unlocked a new item.	Take 25 items from Angel rooms	380	All
Extension Cord		Unlocked a new item.	Have The Battery, 9 Volt, and Car Battery in your collection	381	All
Flat Stone		Unlocked a new item.	Acquire Rubber Cement 5 times	382	All
Sacrificial Altar		Unlocked a new item.	Take 50 devil deals	383	All
Lil Spewer		Unlocked a new item.	Die to your own explosion from Ipecac, Bob's Rotten Head, or Horf! pill	384	All
Blanket		Unlocked a new item.	Sleep in 10 beds	385	All
Marbles		Unlocked a new item.	Use 5 Gulp! pills in one run	386	All
Mystery Egg		Unlocked a new item.	Spawn three charmed enemies in the same room	387	All
Rotten Penny		Unlocked a new item.	Have 20 blue flies at the same time	388	All
Baby-Bender		Unlocked a new item.	Use I - The Magician or Telepathy for Dummies while already having homing tears (Sources of this effect include I - The Magician, Telepathy for Dummies, Spoon Bender, Sacred Heart, or Godhead).	389	All
The Forgotten		Unlocked a new character.	It's complicated	390	All
Bone Heart		Unlocked a new item.	It's complicated	391	All
Marrow		Unlocked a new item.	Defeat Mom's Heart or It Lives! on hard mode as The Forgotten	392	All
Slipped Rib		Unlocked a new item.	Defeat Isaac as The Forgotten	393	All
Pointy Rib		Unlocked a new item.	Defeat Satan as The Forgotten	394	All
Jaw Bone		Unlocked a new item.	Defeat ??? as The Forgotten	395	All
Brittle Bones		Unlocked a new item.	Defeat The Lamb as The Forgotten	396	All
Divorce Papers		Unlocked a new item.	Complete the Boss Rush as The Forgotten	397	All
Hallowed Ground		Unlocked a new item.	Defeat Hush as The Forgotten	398	All
Finger Bone		Unlocked a new item.	Defeat Ultra Greed as The Forgotten	399	All
Dad's Ring		Unlocked a new item.	Defeat Ultra Greedier as The Forgotten	400	All
Book of the Dead		Unlocked a new item.	Defeat Delirium as The Forgotten	401	All
Bone Baby		Unlocked a new co-player baby.	Earn all Hard Mode Completion Marks as The Forgotten	402	All
Bound Baby		Unlocked a new co-player baby.	Defeat Mega Satan as The Forgotten	403	All

Playstation Trophies

Name	Image	Unlock
Platinum		Obtain all trophies
Isaac's Tears		Kill Isaac (Boss) with Isaac
Mom's Knife		Kill Satan with Isaac
Isaac's Heart		Kill Isaac (Boss) with The Lost
The Mind		Kill Satan with The Lost
Magdalene		Have 7 or more heart containers at one time
The Relic		Kill Isaac (Boss) with Maggy
Guardian Angel		Kill Satan with Maggy
Cain		Hold 55 coins at one time
The Coin Bag		Kill Isaac (Boss) with Cain
The Bomb Bag		Kill Satan with Cain
Judas		Kill Satan for the 1st time
The Guillotine		Kill Isaac (Boss) with Judas
Judas' Tongue		Kill Satan with Judas
Eve		Don't pick up any hearts for 2 floors in a row
Eve's Bird Foot		Kill Isaac (Boss) with Eve
The Razor		Kill Satan with Eve
Samson		Beat 2 floors in a row without taking damage
Bloody Lust		Kill Isaac (Boss) with Samson
Blood Rights		Kill Satan with Samson
Azazel		Make 3 deals with the devil in one run
Satanic Bible		Kill Isaac (Boss) with Azazel
Daemon's Tail		Kill Satan with Azazel
Lazarus		Have 4 or more soul hearts at one time
Lazarus' Rags		Kill Isaac (Boss) with Lazarus
Broken Ankh		Kill Satan with Lazarus
Eden		Beat Chapter 4 for the 1st time
Blank Card		Kill Isaac (Boss) with Eden
The Book of Secrets		Kill Satan with Eden
Something From The Future		Beat The Basement 40 times.
Something Cute		Beat Chapter 2 30 times
Something Sticky		Beat Chapter 3 20 times
Basement Boy		Beat Chapter 1 without taking damage
Spelunker Boy		Beat Chapter 2 without taking damage
Dark Boy		Beat Chapter 3 without taking damage
Mama's Boy		Beat Chapter 4 without taking damage
Dead Boy		Beat The Chest or Dark Room without taking damage
Challenges		Beat all 20 Challenges
Boss Rush		Beat the Boss Rush
Dark Room		Beat the Dark Room
The Chest		Beat The Chest
Lost Poster		Beat Dark Room with Isaac
Little Baggy		Collect 2 of either roid rage, the virus, growth hormones, experimental treatment or speed ball
The Womb		Kill Mom for the 1st time
The Halo		Kill Mom using The Bible
Transcendence		Kill Mom's Heart 3 times
Everything is Terrible		Kill Mom's Heart 5 times
A Quarter		Kill Mom's Heart 8 times
A Fetus in a Jar		Kill Mom's Heart 9 times
Blue Baby		Kill Mom's Heart 10 times
It Lives		Kill Mom's Heart 11 times
Forget Me Now		Kill Satan with ???
The Book of Sin		Kill all 7 Sins
The Polaroid		Kill Isaac (Boss) 5 times
The Negative		Kill Satan 5 times
Golden God		Kill ??? and The Lamb
Platinum God		Collect all items in the game, unlock all of the secrets and Endings minus The Lost and his 7 unlockable items
The Lost		Unlock The Lost
Real Platinum God		Collect every Item and unlock every ending.

Notes

• Each achievement is color-coded based on the requirements for unlocking their respective secrets:
  • Tan: Random/Miscellaneous unlocks
  • Tan with blood stain: Mom's Heart/It Lives! on Hard unlocks
  • Olive-Green: character unlocks
  • Dark Red: Mom's Heart/Womb Ending unlocks
  • Grey: Isaac unlocks
  • Black: Satan unlocks
  • Dark Blue: ??? unlocks
  • Purple: The Lamb unlocks
  • Pale Green: Boss Rush unlocks
  • Pale Blue: Hush unlocks
  • Orange: Greed Mode unlocks
  • Orange with blood stain: Greedier Mode unlocks
  • White: Delirium unlocks
  • Red: Mega Satan unlocks/accomplishments
  • Dark Yellow: All Hard Mode marks unlocks
  • Bright Yellow: Greed Machine unlocks
  • Bluish Purple: Challenge Unlocks
• At the stats screen, pressing Alt + F2 will sync your unlocks with your steam achievements. Should you have steam achievements for secrets you haven't unlocked ingame, they will be unlocked by doing this.
• There are a total of 178 unlockable secrets.
  • Afterbirth added 98 unlockable secrets for a total of 276.
    • Afterbirth+ added 63 unlockable secrets for a total of 339.
      • Booster Pack #5 added 64 unlockable secrets for a total of 403.
• Using a seed prevents the unlocking of achievements for that run.
  • Certain cosmetic and difficulty-increasing special seeds will still allow unlocks.
• Playing with any enabled mod prevents any achievements from being unlocked until you have beaten Mom.
• Although not technically an achievement, getting 1000000% for all 3 save files will result in a special 3,000,000%!!! graphic on the save file selection screen. Simple file manipulation (copying save files and renaming them) in the Steam Remote folder (or Afterbirth+ folder if steamcloud is set to 0) will work. An easy way to do this is to earn all achievements on one file, go to the other files, enter the stats screen, and press Alt + F2. This will sync Steam achievements with in-game unlocks and will therefore grant all achievements for that file.
• Achievements 340-348 don't exist in the PS4 version, resulting in the content already being "unlocked" even on new save files.
• Achievements are disabled during Victory Laps.

Trivia

• Despite being a Boss Rush unlock for Lazarus, Missing No.Randomizes all passive items upon pickup and at the start of each succeeding floor.'s achievement color is bluish purple, a color normally used for challenge-related unlocks. This is likely in reference to the item's glitched nature and origins.
• The 5 Nights at Mom's achievement is a reference to Five Nights at Freddy's.
• The Mr. Resetter achievement may be a reference to Mr. Resetti from the Animal Crossing series.
• The Something Wicked This Way Comes quote is most likely a reference to the same quote from one of the witches from Shakespeare's play "Macbeth."