The Binding of Isaac: Afterbirth
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Issues: Incomplete list of additions and changes.
The Binding of Isaac: Afterbirth is the expansion to The Binding of Isaac: Rebirth. The DLC was released on October 30th, 2015 and costs $10.99/£7.99. It was released on May 10, 2016 on Xbox One and PS4.
For a list of the pre-release blog posts, see The Binding of Isaac: Afterbirth (Pre-Release).
- 1 Features
- 2 Additions
- 3 Changes
- 4 Gallery
- 5 Trivia
Features[edit | edit source]
- Greed Mode: A new game mode with a heavy focus on risk/reward, featuring a new ending and final boss.
- Blue Womb: A new area, featuring a new ending and final boss.
- Daily Runs: Daily seeded runs with online leaderboards.
- Two new characters, Lilith and Keeper.
- 95 new items and 29 new trinkets.
- New pickups, chests, pills, and cards.
- 10 new challenges.
- 4 new alternate chapters: Burning Basement, Flooded Caves, Dank Depths, and Scarred Womb.
- Many new room layouts including tiny rooms, long hallways, and L-shaped rooms.
- New room types like trap rooms, double treasure rooms, and closets.
- New special seeds, along with a seed code combo page.
- An expanded soundtrack.
- An extra HUD option, allowing items picked up to be displayed on-screen.
- 9 new transformations.
- New bosses, along with new variations of bosses introduced in Rebirth.
- New monsters.
- Updated item combo system.
- New achievements.
- New co-op babies.
- An improved collection page that shows item descriptions.
Additions[edit | edit source]
Characters[edit | edit source]
|Damage||3.5 (*1.00)||3.5 (*1.20)|
|Starting Pickups||None|| x1 Bombs|
|Starting Item(s)|| Incubus,
Box of Friends
| Triple shot,|
Items[edit | edit source]
95 new items were added in the expansion: 19 activated items and 76 passive items.
Activated Collectibles[edit | edit source]
|Box of Friends||357||Double your friends||Upon use, duplicates all of Isaac's familiars for the current room.||4|
|D12||386||Rerolls rocks||Re-rolls all rocks in the current room into other random objects, such as bomb rocks, metal blocks, TNT, or poops.||3|
|D7||437||Reroll rewards!||Restarts the current room and brings back all enemies, allowing more rewards to be acquired by completing the room.||3|
|D8||406||Reroll stats||Re-rolls Isaac's speed, range, tears and damage.||4|
|Diplopia||347||Double item vision||Duplicates all pickups and item pedestals in the room.||One time use|
|Friendly Ball||382||Gotta fetch 'em all!||Throwing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be charmed until it dies, persisting between floors.||3|
|Glass Cannon||352||Be gentle...||When used, reduces Isaac's health to half a heart (including soul and black hearts) and fires one large piercing spectral tear that does a lot of damage. The damage done by Glass Cannon scales with Isaac's damage (at base damage it does 45 damage).||4 seconds|
|Glowing Hour Glass||422||Turn back time||When used, this item will rewind time, put Isaac back in the previous room, and undo anything that happened in the current room. Any health, pickups, or items gained or lost will be reset back to the previous state.||2|
|Jar of Flies||434||Gotta catch 'em all?||Every time Isaac kills an enemy, a fly will be added to the jar, up to a maximum of 20. Using the Jar of Flies will release all the flies that are currently in the jar as friendly blue flies that will damage enemies.||0|
|Kidney Bean||421||Love toots!||Upon use, Isaac farts, charming all nearby enemies.||2|
|Mega Bean||351||Giga fart!||When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies near Isaac, and send a wave of spikes that deals 10 damage across the room in the direction Isaac is facing.||3|
|Mega Blast||441||Laser breath||Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active.||12|
|Mine Crafter||427||Booom!||When used, places an explosive TNT barrel that can be pushed and used to destroy rocks or damage enemies. If used a second time in the same room while the previous TNT barrel is still intact, it will remotely explode the TNT.||1|
|Mom's Box||439||What's inside?||When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.||4|
|Placebo||348||Pill mimic||When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes.||4|
|Tear Detonator||383||Remote tear detonation!||When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head.||1|
|Teleport 2.0||419||I-Teleport!||When used, teleports Isaac to a random room that has not been explored yet. If all rooms are explored, including secret rooms, it will teleport Isaac to the Devil or Angel room. If all rooms are explored, including the Devil or Angel room, it will teleport Isaac to the I AM ERROR room. If used in a room with enemies, it will teleport Isaac out and back into the exact same room.||4|
|Ventricle Razor||396||Short cutter||Can be used to place an orange portal and a blue portal. Upon entering a portal, Isaac is teleported to the other portal.||0|
|Wooden Nickel||349||Flip a coin||When used, has a 50% chance to drop one random type of coin (penny, nickel or dime).||1|
Passive Collectibles[edit | edit source]
|8 Inch Nails||359||Stick it to 'em!||+1.5 Damage Up. Replaces Isaac's tears with nails, which have increased knockback.|
|Athame||408||Call to the void||Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.|
|Betrayal||391||Turn your enemy||Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.|
|Binky||438||Memories...||Tears up, adds 1 soul heart, and decreases Isaac's size.|
|Black Powder||420||Spin the black circle!||Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it.|
|Bomber Boy||353||Explosive blast!||+5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects troll bombs.|
|Bumbo||385||Bumbo want coin!||Spawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.|
|Bursting Sack||377||Spider love||Spider enemies no longer target or deal contact damage to Isaac.|
|Cambion Conception||412||Feed them hate||After taking damage a certain amount of times, a permanent demonic familiar spawns.|
|Car Battery||356||Double charge!||Causes Isaac's activated item to activate twice on each use.|
|Censer||387||Peace be with you||Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.|
|Chaos||402||!!!||Chaos causes items to be chosen from random item pools. When picked up, drops between 1-6 random pickups on the floor.|
|Charged Baby||372||Bbbzzzzzt!||A familiar baby that drops a battery every 4 rooms. Has a small chance to freeze all enemies in the room when hit.|
|Circle of Protection||423||Protect me from myself||Surrounds Isaac with a large white halo around him that pulsates. With each pulse, the halo deals contact damage to enemies equal to Isaac's damage. Each pulse also converts any enemy shots touching the ring into friendly purple homing tears.|
|Continuum||369||Transcendent tears||+2.25 Range Up. +1.5 Tear Height. Isaac's tears travel through walls and appear out of the opposite wall. Isaac's tears also travel over rocks and objects.|
|Crack Jacks||354||Don't swallow the prize!||Adds one heart container and drops a random trinket.|
|Crown of Light||415||The untainted gain power||Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.|
|Curse of the Tower||371||You feel cursed...||Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.|
|Dead Eye||373||Accuracy brings power!||Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot.|
|Deep Pockets||416||More stuff to carry!||Allows Isaac to carry two cards or pills (or a combination of both) at the same time.|
|Eden's Blessing||381||Your future shines brighter||Tears up. Grants a random item at the start of the next run.|
|Empty Vessel||409||I reward an empty vessel||While Isaac has no red hearts, this item grants flight and a random chance to activate an invincibility shield for a few seconds. If Isaac gains any red hearts, these benefits will disappear.|
|Epiphora||368||Intensifying tears||Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount.|
|Evil Eye||410||Eye shot!||While firing tears, Isaac has a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac. The eye will be destroyed if it comes into contact with an enemy or obstacle.|
|Explosivo||401||Sticky bomb shot!||Isaac's tears have a chance to stick to enemies and explode.|
|Farting Baby||404||It farts!||A familiar that follows Isaac and blocks tears. If a tear hits Farting Baby, there is a high chance for it to fart, which will either knock back, poison, or charm all nearby enemies.|
|Fate's Reward||361||Your fate beside you||A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage.|
|Friend Zone||364||Friendly fly||A white orbiting fly which deals 3 contact damage per tick to enemies. This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone.|
|Fruit Cake||418||Rainbow Effects!||Isaac's tears gain a random effect that changes every shot.|
|GB Bug||405||Game breaking bug, right away!||A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.|
|Glitter Bombs||432||Prize Bombs!||Gives Isaac 5 bombs, and makes Isaac's bombs have a chance to drop random pickups or charm enemies when they explode.|
|God's Flesh||398||Shrink shot||Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.|
|Head of the Keeper||429||Penny tears!||Isaac's tears become coins and now have a chance to drop pennies on the floor upon successfully hitting an enemy.|
|Holy Light||374||Holy shot!||Isaac has a random chance to fire a Holy tear, which when it hits an enemy, will spawn a Crack the Sky style light beam on the same enemy, dealing damage.|
|Host Hat||375||Nice hat!||A host familiar that sits on Isaac's head and has a random chance to block enemy shots and retaliate with 3 tears. Grants immunity to explosions.|
|Immaculate Conception||413||Feed them love||Upon picking up a certain amount of health, spawn a permanent angelic familiar.|
|Incubus||360||Dark friend||A demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects.|
|Key Bum||388||He wants your keys!||Spawns a portable key master that follows Isaac and collects keys, giving random chests in return.|
|Kidney Stone||440||Matt's kidney stone||Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. In the burst of tears is a kidney stone which deals a lot of damage.|
|Lil Gurdy||384||A gurd of your own!||Gives Isaac a Gurdy familiar that will charge around the room dealing contact damage to enemies. Lil Gurdy is charged by holding down a fire button and letting go. The longer the button is held, the faster Lil Gurdy will fling itself across the screen. Lil Gurdy can pass over objects and obstacles in the room.|
|Lil' Loki||435||4-way buddy!||A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern.|
|Lost Fly||365||Lost protector||A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room. If any enemies walk into its path, it will deal 7 contact damage per tick. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle.|
|Lusty Blood||411||Their blood brings rage!||Each time Isaac kills an enemy, Isaac's damage increases for the current room.|
|Marked||394||Directed tears||Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player. This allows for a full 360 degree tear firing radius. Can be overridden by other tear modifiers such as Mom's Knife or Brimstone.|
|Maw of the Void||399||Consume thy enemy!||+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.|
|Milk!||436||Don't cry over it...||A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.|
|Mom's Pearls||355||Range + luck up||+1.25 Range Up. +0.5 Tear Height. +1 Luck Up.|
|More Options||414||There are even more options!||Two items spawn in every Treasure Room. Only one can be taken; the other will disappear.|
|Mr. Dolly||370||Range + tears up||Tears and Range up. Spawns 3 random types of hearts on the floor when picked up.|
|Multidimensional Baby||431||ydduB Buddy||Spawns a familiar that will follow Isaac's movements on a 2.5 second delay. Tears that pass through the baby will be doubled and increase in speed.|
|My Shadow||433||Me! And my shaaaadow!||Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black Charger familiar that will attack enemies. The Charger will be killed if it is damaged too much.|
|Night Light||425||Scared of the dark?||A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.|
|No. 2||378||Uh oh...||Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.|
|Papa Fly||430||Turret follower||A blue fly familiar follows Isaac's movements on a 3 second delay. Papa Fly will fire tears at nearby enemies.|
|Pay to Play||380||Money talks||This item turns all doors that require a key into doors which need a coin to enter instead. This affects shops, item rooms, libraries and other key doors.|
|PJs||428||You feel cozy||Adds 4 Soul Hearts and fully restores Isaac's red health.|
|Pupula Duplex||379||Wide shot||Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).|
|Purity||407||Aura stat boost||This item will boost one of Isaac's stats depending on the color of the aura around him. The aura will disappear upon taking damage and will reappear with a random color upon entering a new room. A red aura boosts damage, a blue aura boosts rate of fire, a yellow aura boosts speed, and an orange aura boosts range.|
|Obsessed Fan||426||Follows my every move...||A purple fly familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies.|
|Restock||376||Never ending stores!||Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.|
|Rune Bag||389||Rune generator||A bag that follows Isaac and drops a random mystic rune every 3 rooms.|
|Sack Head||424||More sacks!||Greatly increases the chance to find sacks.|
|Scatter Bombs||366||'We put bombs in your bombs!'||Adds 5 bombs. Isaac's bombs explode into 2-4 tiny bombs|
|Seraphim||390||Sworn friend||An angel familiar which follows Isaac and fires homing tears which deal 10 damage at -25% shot speed and a reduced fire rate.|
|Serpent's Kiss||393||The kiss of death||Tears now have a random chance to apply a poison effect, causing 4 or 6 damage per tick to enemies (Similar to The Common Cold item). Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick). Enemies that were poisoned have a chance to drop a black heart when killed.|
|Sticky Bombs||367||Egg sack bombs!||+5 bombs. Bombs stick to enemies and spawn 2-4 blue spiders if they kill an enemy.|
|Spear of Destiny||400||Your destiny||In addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.|
|Spider Mod||403||Mod buddy!||Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.|
|Succubus||417||Damage booster||Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier.|
|Sworn Protector||363||Protective friend||An orbital angel which does 7 contact damage per tick and blocks enemy shots. When it blocks a shot, it has a very small chance to drop an eternal heart.|
|Tech X||395||Laser ring tears||Tears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the size of the ring.|
|Toxic Shock||350||Mass poison||Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.|
|Tractor Beam||397||Control your tears||Isaac emits a beam from his face. Isaac's tears travel in the path of the beam.|
|The Wiz||358||Double wiz shot!||Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard? pill. Isaac's tears also travel above all obstacles.|
|Zodiac||392||The heavens will change you||Zodiac will give Isaac a random zodiac item effect that changes after every floor.|
Trinkets[edit | edit source]
29 new trinkets were added in the expansion.
|Blasting Cap||73||Pop! Pop!||Exploding bombs have a chance to drop another bomb pickup.|
|Black Feather||80||With darkness comes power||Increases Isaac's damage for possessing certain evil items.|
|Blind Rage||81||Blind to damage||Increases invincibility time after getting hit.|
|Blister||77||Bounce back!||Increases knockback of tears.|
|Brown Cap||90||Fartoom!||Poop will explode after being destroyed.|
|Bob's Bladder||71||Creepy bombs||Leaves a pool of green creep under all bombs Isaac places, which damages enemies that walk over it.|
|Child Leash||89||Keep your friends close...||Causes familiars to stay closer to each other.|
|Cracked Dice||67||You feel cursed... kinda.||Whenever Isaac gets hit, there is a chance that the effect of The D6, D8, D12, or D20 gets activated.|
|Endless Nameless||79||I'm stuck in a loop...||When Isaac uses a pill, card, or rune, there is a chance to spawn another one of the same type.|
|Error||75||Effect not found?||Gives a random trinket effect each room.|
|Faded Polaroid||69||You feel faded||Occasionally causes Isaac to blend into the ground, which briefly confuses all enemies in the room.|
|Golden Horse Shoe||82||Feel lucky?||+15% chance for a Treasure Room with two items to spawn.|
|Karma||85||Karma up||Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar. Increases the chance that donating to a Donation Machine will increase Isaac's luck.|
|Lazy Worm||66||Pft||Tear shot speed is greatly reduced.|
|Lil Larva||86||The poop is moving...||Spawns a blue fly from every pile of poop Isaac destroys.|
|Louse||70||Itchy, tasty...||Occasionally spawns a Blue Spider.|
|Mom's Locket||87||You feel her love||Grants half a red heart each time a key is used. Converts half red heart pickups into full red hearts.|
|NO!||88||Never again!||Removes all active items from every item pool.|
|Poker Chip||76||It's double down time!||Chests have a 50% chance of paying out with extra pickups and a 50% chance of paying out with nothing or enemies.|
|Rainbow Worm||64||Bleep Bloop Blop||Isaac's tears gain a random worm effect that changes every 3 seconds.|
|Rib of Greed||84||Feels greedy||Prevents Greed and Super Greed from appearing in Shops and Secret Rooms.|
|Safety Scissors||63||Fuse Cutter||Troll bombs turn into Bomb pickups before they explode. Mega troll bombs turn into 1+1 free bombs before they explode.|
|Second Hand||78||Extended stat effect time!||Increases the time that status effects stay on enemies.|
|Shiny Rock||62||It shines for its brothers||Tinted rocks and rocks with Crawl Spaces will flash white every 10 seconds.|
|Store Key||83||Stores are open||Automatically opens all Shops.|
|Stud Finder||74||The ground below feels hollow...||Increases the chance to find a Crawl Space.|
|Super Magnet||68||It Pulls||Pulls enemies and pickups towards isaac.|
|Tape Worm||65||Floooooooooop!||Doubles Isaac's range and halves his tear height.|
|Watch Battery||72||Lil charge||Increased chance of batteries spawning. Has a chance to add an extra charge to Isaac's activated item upon completing a room.|
Pickups[edit | edit source]
Pickups & Chests[edit | edit source]
|Gold Heart||Gold Hearts are the rarest variation of a heart. They are unlocked by completing the challenge XXXXXXXXL. They always appear as full hearts and, once picked up, drop money the next time Isaac loses a Heart. A Golden Heart appends to the end of the health bar, surrounding it in a golden glow.|
|Lucky Penny||A Lucky Penny increases luck by 1 when picked up. Unlocked by donating 1 coin to the Greed Machine. Bumbo and Bum Friend are unable to pick up Lucky Pennies; they instead hover over them attempting to pick them up. Humbling Bundle does not double lucky pennies.|
|Sticky Nickel||A Nickel that will flip upside-down when Isaac tries to collect it. Afterwards, it will get stuck on the ground, unable to be picked up unless blasted off the ground with an explosion. Unlocked by completing Boss Rush with Keeper. It won't reduce the spawn rate of regular Nickels: rather, Pennies have an additional chance to become Sticky Nickels.|
|Gold Bombs||Gold bombs will not add to the player's bomb count, but when picked up, they will give the player unlimited bombs for the duration of the current floor, similarly to Golden Keys. They are unlocked by completing the challenge Blue Bomber.|
|Angel Chests||Angel Chests are similar in appearance to Gold Chests, except they glow bright blue instead of gold, like a soul heart. They require one key to unlock, but can be reopened a random amount of times, each time requiring another key. They can be found in Angel rooms and rarely in a normal room. Their loot is similar to Golden Chests, but they can also drop nothing upon opening. If they contain nothing or an item, they will no longer be able to be reopened.|
|Spike Chests||Spike Chests are purple colored chests with spikes protruding from them that will deal damage to Isaac upon opening (unless he has the Holy Mantle active, which nullifies the damage, or if found in The Chest, where they are free to open). They can be rarely found upon completing a room or in greed mode shops. Their loot is similar to Brown Chests. Unlike other chests, they do not appear on the minimap.|
|Mystery Sack||The Mystery Sack will spawn 1-4 pickups upon touching it. Sack Head greatly increases the chances of finding sacks.|
Pills[edit | edit source]
Makes Isaac take a full heart of damage from all sources for the current room. Unlocked by completing Challenge #24: PAY TO PLAY.
|Friends Till The End!|
Spawns three Blue Flies.
Spawns Blue Spiders equal to the number of enemies in the room. If there are no enemies in the room, spawns 1-3 Blue Spiders.
|One Makes You Small|
Decreases Isaac's size and increases the pitch of his voice. This effect decreases the size of Isaac's hitbox.
|One Makes You Larger|
Increases Isaac's size and decreases the pitch of his voice. This effect does not increase the size of Isaac's hitbox.
Activates an effect similar to The Gamekid.
For a short time, poop spawns wherever Isaac moves, like Explosive Diarrhea but with poop. A higher move speed means you can touch more tiles in the same time. A pun on laxatives. Unlocked by completing Challenge #25: Have a Heart.
Briefly pixelates the screen 3 times over 30 seconds.
Gives the Curse of the Maze effect for the remainder of the floor. The effect can stack with other curses. If no other curses are active for the floor, Curse of the Maze will appear under the level name when TAB is held. This effect cannot be negated by Black Candle. Unlocked by completing Challenge #25: Have a Heart.
Cards & Runes[edit | edit source]
|? Card||48||Double Active||When used, copies the effect of Isaac's currently held activated collectible item.|
|Get out of Jail Free Card||47||Open Sesame||Upon use, opens all doors in the current room (including the golden door at The Chest / Dark Room), similar to Dad's Key.|
|Emergency Contact||50||Help from above||When used, will cause two Mom's Hands to come down and grab two random enemies.|
|Dice Shard||49||D6 + D20||Upon use, activates the effects of the D6 and the D20 at the same time.|
|Blank Rune||40||Beat challenge #30 (The unlock is bugged and actually unlocks Kidney Stone in Afterbirth. Fixed in Afterbirth Plus.)||???||Grants a random rune effect. Has a 25% chance to spawn another Blank Rune upon use.|
Transformations[edit | edit source]
|Transformation||Appearance||Transformation effect||Item||Icon||Item effect||Recharge|
|Bob's Rotten Head||Upon use, Isaac holds a poison bomb which can be thrown towards any of the four cardinal points and explodes on impact.||3|
|Bob's Brain||Spawns a familiar that charges forward when shooting tears, explodes upon contact with an enemy and poisons them. Respawns after few seconds.|
|Bob's Curse||Gives 5 bombs and grants all bombs poison effect.|
|Ipecac||Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.|
|Brother Bobby||Follows Isaac around shooting normal tears.|
|Harlequin Baby||Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern.|
|Headless Baby||Familiar that follows Isaac, leaving blood creep on the ground.|
|Little Steven||Spawns a familiar that follows Isaac around and fires homing tears.|
|Mongo Baby||Summons a familiar that copies the tears of Isaac's other familiars.|
|Rotten Baby||A familiar that spawns blue flies.|
|Sister Maggy||A familiar that follows Isaac around shooting blood tears.|
|God's Flesh||Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.|
|Mini Mush||Increases Speed and Shot Height and decreases Isaac's size, but lowers Range.|
|Magic Mushroom||Increases all stats and enlargens Isaac.|
|Odd Mushroom (Thin)||Increases Tears and Speed while reducing Damage.|
|Odd Mushroom (Large)||Grants an empty heart container. Increases damage, range and shot height while reducing speed.|
|1up!||Gives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1up!.|
|Blue Cap||Grants 1 heart container and increases tears, but decreases shot speed.|
|The Nail||Adds one soul heart and allows the breaking of Rocks and damaging enemies by simply walking over them. Increases Damage and decreases Speed. All effects except for the Soul Heart wear off upon leaving the room.||6|
|The Mark||Increases Damage and Speed, plus adds one Soul Heart.|
|Missing Page 2||Gives 1 black heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.|
|The Pact||Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.|
|Pentagram||Increases damage and increases the chance for a Devil or Angel Room to appear.|
|Spirit of the Night||Grants spectral tears and flight.|
|Maw of the Void||+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.|
|Abaddon||Increases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears.|
|Brimstone||Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.|
|Flush!||Changes all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie.||6|
|The Poop||Spawns a pile of poop where the character is standing and knocks nearby monsters back. May yield pickups like regular poop.||1|
|E Coli||Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.|
|The Bible||Upon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.||6|
|Dead Dove||Grants spectral tears and flight.|
|Guardian Angel||Spawns an orbital familiar that blocks enemy projectiles, deals contact damage to enemies and increases the speed of all orbital familiars.|
|Holy Grail||Grants flight and one heart container.|
|Holy Mantle||Automatically negates first taken damage in every room.|
|Mitre||Grants a chance of converting any red hearts pickups into soul hearts instead.|
|Rosary||Adds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.|
|Sworn Protector||An orbital angel which does 7 contact damage per tick and blocks enemy shots. When it blocks a shot, it has a very small chance to drop an eternal heart.|
|The Halo||Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.|
|Adrenaline||Increases damage based on how many empty heart containers Isaac has.|
|Euthanasia||Adds a chance to fire needles. If a needle kills an enemy, it bursts into more needles.|
|Experimental Treatment||Randomly increases and decreases some of the character's stats. There will always be at least one stat increase and one decrease and the same stats can be increased/decreased multiple times.|
|Growth Hormones||Increases damage by 1 and speed by 0.4.|
|Roid Rage||Increases speed by 0.6, range by 5.25, and tear height by 0.5.|
|Speed Ball||Increases speed by 0.3 and shot speed by 20%.|
|Synthoil||Increases damage by 1, range by 5.25, and tear height by 0.5.|
|The Virus||Inflicts poison to enemies who make contact with Isaac. Speed down.|
|Mom's Bottle of Pills||Gives Isaac a random pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.||6|
|Mom's Bra||Upon use, petrifies all enemies in the current room for approximately 4 seconds.||3|
|Mom's Pad||Upon use, inflicts fear to all enemies in the room for 5 seconds.||3|
|Mom's Wig||Adds a chance to spawn blue spiders when firing tears. Restores 1 red heart.|
|Mom's Eye||Allows Isaac to fire tears from the back of his head.|
|Mom's Purse||Allows Isaac to hold 1 additional trinket.|
|Mom's Contacts||Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.|
|Mom's Knife||Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.|
|Mom's Heels||Increases range.|
|Mom's Eyeshadow||Tears have a chance to charm enemies.|
|Mom's Perfume||Adds a chance to shoot fear tears and decreases tear delay by 1.|
|Mom's Key||Spawns 2 keys. Generates additional pickups from chests.|
|Mom's Lipstick||Increases range and shot height.|
|Mom's Underwear||Increases range.|
|Mom's Coin Purse||Spawns 4 random pills around Isaac.|
|Mom's Pearls||+1.25 Range Up. +0.5 Tear Height. +1 Luck Up.|
|Mom's Razor||Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.|
|Bum Friend||A portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickup after collecting a coin. Does not spawn collectibles.|
|Dark Bum||Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider.|
|Key Bum||Spawns a portable key master that follows Isaac and collects keys, giving random chests in return.|
- 1: Image depicts the familiar. This transformation does not alter Isaac's appearance.
NPCs[edit | edit source]
Monsters[edit | edit source]
Many new monsters were added in the expansion. Additionally, several new champion types were added.
| Dart Fly
||Flies towards Isaac and attempts to mimic his movements. Deals contact damage.|
| Swarm Fly
||Follows Isaac in large groups and deals contact damage.|
| Drowned Boom Fly
||Flies around the room diagonally, dealing touch damage. Upon death, explodes, fires four blood shots in the cardinal directions, and spawns a Drowned Charger.|
| Corn Dip
||Quickly dashes in random directions, dealing contact damage.|
| Dank Squirt
||Dashes towards the player and deals contact damage. Spawns 2 Clots upon death.|
||Pops out of the ground in random locations, creating a small rock wave. Fires an explosive Ipecac shot at Isaac if he is in sight.|
||Pops out of the ground in random locations and spits a blood shot at Isaac or spawns a Dart Fly if Isaac is in sight.|
| Drowned Hive
||Walks around the room, avoiding Isaac while spawning Drowned Chargers. Spawns a Drowned Charger upon death.|
||Flies around the room diagonally, occasionally spitting out a Dart Fly.|
| Flaming Gaper
||Walks towards Isaac, dealing contact damage. Usually turns into a Pacer or a Gusher upon death.|
||Walks towards Isaac, dealing contact damage and leaving behind a trail of damaging red creep. Occasionally shoots a blood shot towards Isaac.|
| Black Bony
||Wanders around the room and throws three bones in a row at Isaac when he is in sight. Explodes upon death.|
| Dank Death's Head
||Moves diagonally around the room, dealing contact damage. Needs to be killed to complete the room.|
| Flesh Death's Head
||Moves diagonally around the room, dealing contact damage. Explodes into 6 blood shots in all directions upon death. Can be killed, but also dies when the room is cleared.|
| Fat Bat
||Slowly flies towards Isaac. Shoots when Isaac aligns diagonally with it and will actively try to avoid Isaac's shots.|
| Red Ghost
||Disappears, then reappears near Isaac and fires a brimstone laser.|
| Flaming Fatty
||Slowly walks towards Isaac. Occasionally farts, which pushes Isaac and adjacent enemies away. Has a chance to leave behind a damaging flame upon death.|
| Conjoined Fatty
||Slowly walks towards Isaac. Occasionally spits a line of damaging green creep towards Isaac. Turns into a regular Fatty upon death.|
| Blue Conjoined Fatty
||Slowly walks towards Isaac and occasionally spits a homing Ipecac shot at Isaac.|
| Dank Globin
||Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, spawns a spider, and leaves a puddle of slowing black creep. Will regenerate after a short period of time if not killed quickly.|
| Black Globin
||Chases Isaac, dealing a full heart of contact damage and spawning spiders. Upon taking enough damage, it separates into a head and body. The head slides towards Isaac, leaving a trail of damaging red creep. The body wanders around aimlessly, occasionally spawning spiders.|
| Black Globin's Body
||Walks aimlessly around the room, occasionally spawning spiders.|
| Bone Knight
||Moves erratically around the room, charges toward Isaac when in line of sight, and leaves behind a trail of damaging red creep. Can only be damaged from behind.|
| Mega Clotty
||Slowly moves around the room, occasionally hopping and firing 6 blood shots in all directions. Splits into two Clotties upon death.|
| Mom's Dead Hand
||Falls from the ceiling. If it lands on Isaac, it deals damage and teleports the player back to the spawn room of the floor. If it doesn't land on Isaac, it spawns several rock waves that travel outwards. Spawns several spiders upon death. Entering a room containing Mom's Dead Hand will warn the player with Mom's laugh.|
| Drowned Charger
||Slowly moves around the room, charging at Isaac when he gets in its line of sight. Explodes into four blood shots in the ordinal directions upon death.|
| Scarred Para-Bite
||Moves towards Isaac, dealing contact damage and firing short-range blood shots. Can burrow underground and reappear elsewhere.|
| Scarred Guts
||Attaches itself to a wall or obstacle and rolls around it, leaving a trail of damaging red creep.|
| Scarred Double Vis
||Charges and fires a Brimstone laser which fires from all four sides when Isaac gets in its line of sight.|
||Slides around the room, occasionally stopping to spew a fountain of short-range blood shots in all directions or to spit a line of damaging red creep. Spawns a Host upon death.|
||Slowly drifts towards Isaac, frequently firing 5 blood shots in quick succession towards Isaac. Tries to avoid Isaac's shots and occasionally teleports and reappears elsewhere.|
| Greed Gaper
||Walks towards Isaac, dealing contact damage.|
| Blue Gaper
||Walks towards Isaac, dealing contact damage. Has triple the health of a normal Gaper.|
| Blue Boil
||Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Fires 1-3 blood shots towards Isaac when fully swollen.|
| Hush Fly
||Gathers with other Hush Flies and flies towards Isaac in certain patterns. Can also orbit Hush.|
Bosses[edit | edit source]
Several new bosses were added in the expansion. Additionally, many bosses received new champion variants.
|Rag Man||Little Horn||Dangle||Turdlings|
|The Frail||The Stain||The Forsaken||Brownie|
Beggars[edit | edit source]
Bomb Bums are extremely rare, and ask for bombs. Each bomb donated has a chance to have him drop 1-2 bomb pickups or an item from the Bomb Bum Item Pool. After spawning a pedestal item, the Bomb Bum will disappear and can no longer be donated to.
Environment[edit | edit source]
Chapters[edit | edit source]
|Burning Basement||Flooded Caves|
|Dank Depths||Scarred Womb|
|??? (Blue Womb)|
Challenges[edit | edit source]
|/||Defeat Mom for the 1st time||Gold Heart|
within 16 minutes, otherwise under
constant periodic damage every 10 seconds.
|Defeat Mom for the 1st time||Get out of Jail Free Card|
|23. Blue Bomber||
|Destroy 10 tinted rocks and defeat Mom's Heart 11 times||Gold Bomb|
|24. PAY TO PLAY||
|Defeat Isaac as Cain||2 new pills|
|25. Have a Heart||
|/||Defeat Mom for the 1st time||2 new pills 2|
|26. I RULE!||
|Defeat ??? or The Lamb for the 1st time||Poker Chip|
|Defeat Isaac 5 times||Stud Finder|
|28. PRIDE DAY!||
|/||Defeat Mom for the 1st time||D8|
|29. Onan's Streak||
|Defeat Satan as Judas||Kidney Stone|
|30. The Guardian||
|/||Defeat Mom for the 1st time||Blank Rune|
Changes[edit | edit source]
Items[edit | edit source]
Activated Collectibles[edit | edit source]
Increases chance for a Devil/Angel Room Door to open by 17.5%.
Passive Collectibles[edit | edit source]
- The type of randomized tear changes every 2-3 seconds. The item appears to select two tear effects at once, perhaps staggering the times at which each of those effects change.
- If a run is quit, and then continued, 3 Dollar Bill will keep tear effects for the current room.
- Abel shoots tears towards Isaac regardless of which direction Isaac is shooting.
- Ball of Bandages blocks enemy shots.
- Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.
- Can drop a Gold Bomb.
- Can drop a Gold Bomb.
Interactions[edit | edit source]
Pickups[edit | edit source]
Bombs[edit | edit source]
- Troll Bombs are now given a random amount of time before exploding. Before that they always exploded at a fixed time. This means that if two Troll Bombs spawn at the exact same time right next to each other, there's a high chance one Troll Bomb will blow up before the other, sending that Troll Bomb sliding outwards a bit before exploding.
NPCs[edit | edit source]
Monsters[edit | edit source]
- They only leave behind bones when killed.
Environment[edit | edit source]
Rooms[edit | edit source]
- Double Trouble boss rooms can now contain 2 bosses of different types. Additionally, they can appear as early as Chapter 1.
- Hush is always fought in a 2x2 room and Ultra Greed is fought in a double-sized one (2x1).
- Possible rewards found in the room include:
- Urns might spawn in the room.
- Killing Key key master and shell game beggar no longer applies the 25% bonus.
- Donating to a normal beggar until it pays out with an item on the current floor applies a 10% bonus instead of 25%.
- Donating to a Devil beggar until it pays out with an item on the current floor applies a 10% bonus instead of 25%.
- If this coin flip succeeds, a Devil Room will be generated regardless of the above coin flips.
- "You feel blessed!" fortune in the Sacrifice Room of the current floor applies a bonus:
- If the "You feel blessed!" fortune appeared on the 3rd sacrifice, the chance will be 15%.
- If the "You feel blessed!" fortune appeared on the 5th sacrifice, the chance will be 50%.
- If both "You feel blessed!" fortunes appeared, the chance will be 65%.
- Angel Rooms that spawn after Isaac defeats Mom's Heart or It Lives will be normal Angel Rooms with items or pickups.
- A troll bomb can sometimes appear behind the Angel Statue, blowing it up. If the Angel fights have been unlocked, this will begin the boss fight if the player is not careful or quick enough to move the bomb.
- The clean bedroom occasionally has two clean beds instead of one.
- The trapdoor in a dirty bedroom has a chance to lead to a Crawl Space.
- Occasionally, one Rag Man will spawn inside the dirty bedroom.
- There is a chance that there will only be 2 items to choose from. Additionally, items may be trapped behind rocks or spikes. Items may appear in the corners of the room instead of the center.
- All 15 waves are randomized. Each wave spawns two random bosses from the list. Each boss can only appear once per Boss Rush.
- New layouts:
- If a sack spawns for whatever reason, picking it up will start the Boss Rush. The player can still pick up one of the pedestal items.
- Black Market can no longer be accessed in The Chest and The Dark Room, and therefore cannot be used to collect more items.
Other[edit | edit source]
- When not having red hearts in Devil Room, the price of items switches to soul hearts.
- Krampus has a new attack pattern.
- The Lost is now unlocked by dying in a Sacrifice Room while holding Missing Poster.
- Sacrifice rooms were reworked to give more useful rewards.
Gallery[edit | edit source]
Trivia[edit | edit source]
- Afterbirth is the placenta and fetal membranes discharged from the uterus after the birth of offspring, which might be why the title screen is bloody.
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|