Angel Room (Greed Mode Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
DLC Indicator.png Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
DLC Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Afterbirth† Indicator.png Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Afterbirth† Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Items in this pool can be found in the Angel room in Greed Mode.

Activated Collectibles

Name ID Icon Quote Description Recharge
Book of Revelations 78 Book of Revelations Icon.png Reusable soul protection Adds 1 soul heart, increases the chance for a Devil or Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom). 6

Passive Collectibles

Name ID Icon Quote Description
Blood of the Martyr 7 Blood of the Martyr Icon.png DMG up Increases Damage by 1, and turns Isaac's tears into blood tears.
Celtic Cross 162 Celtic Cross Icon.png You feel blessed Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Censer DLC Indicator.png 387 Censer Icon.png Peace be with you Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
Circle of Protection DLC Indicator.png 423 Circle of Protection Icon.png Protect me from myself Surrounds Isaac with a large white halo around him that pulsates. With each pulse, the halo deals contact damage to enemies equal to Isaac's damage. Each pulse also converts any enemy shots touching the ring into friendly purple homing tears.
Crown of Light DLC Indicator.png 415 Crown of Light Icon.png The untainted gain power Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
Cube of Meat 73 Cube of Meat Icon.png Gotta meat 'em all! Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
Dead Dove 185 Dead Dove Icon.png Flight + spectral tears Grants spectral tears and flight.
Godhead 331 Godhead Icon.png God tears Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
Guardian Angel 112 Guardian Angel Icon.png Extra protection Spawns an orbital familiar that blocks enemy projectiles, deals contact damage to enemies, and increases the speed of all orbital familiars.
Holy Grail 184 Holy Grail Icon.png Flight + HP up Grants flight and one heart container.
Holy Mantle 313 Holy Mantle Icon.png Holy shield Automatically negates first taken damage in every room.
Holy Water 178 Holy Water Icon.png Splash! When Isaac receives damage, the bottle breaks and a puddle of blue creep forms, which damages non-flying enemies, similar to Lemon Mishap. The bottle is reformed upon entering a different room.
Immaculate Conception DLC Indicator.png 413 Immaculate Conception Icon.png Feed them love Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Jesus Juice 197 Jesus Juice Icon.png Damage + range up Increases Damage and Range.
Mitre 173 Mitre Icon.png You Feel Blessed Grants a chance of converting any red hearts pickups into soul hearts instead.
Purity DLC Indicator.png 407 Purity Icon.png Aura stat boost This item will boost one of Isaac's stats depending on the color of the aura around him. The aura will disappear upon taking damage and will reappear with a random color upon entering a new room. A red aura boosts damage, a blue aura boosts rate of fire, a yellow aura boosts speed, and an orange aura boosts range.
Rosary 72 Rosary Icon.png Faith up Adds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.
Sacred Heart 182 Sacred Heart Icon.png Homing shots + DMG up Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
Seraphim DLC Indicator.png 390 Seraphim Icon.png Sworn friend An angel familiar which follows Isaac and fires homing tears which deal 10 damage at -25% shot speed and a reduced fire rate.
Spear of Destiny DLC Indicator.png 400 Spear of Destiny Icon.png Your destiny In addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.
Stigmata 138 Stigmata Icon.png DMG + HP up Increases damage, and adds 1 heart container.
Sworn Protector DLC Indicator.png 363 Sworn Protector Icon.png Protective friend An orbital angel which does 7 contact damage per tick and blocks enemy shots. When it blocks a shot, it has a very small chance to drop an eternal heart.
The Body 334 The Body Icon.png I feel all Adds 3 heart containers.
The Mind 333 The Mind Icon.png I know all Grants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.
The Soul 335 The Soul Icon.png I am all Grants two soul hearts. Isaac now repels enemy projectiles.
Trinity Shield 243 Trinity Shield Icon.png "You feel guarded" Isaac gains a shield that protects him from enemy shots.


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