Angel Room (Greed Mode Item Pool)

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Items in this pool can be found in the Angel Room in Greed mode.

Activated Collectibles

Name ID Icon Quote Description
Book of Revelations 78
Book of Revelations
6 rooms
Reusable soul protection Adds 1 Soul Heart, increases the chance for a Devil or Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom).
Added in Afterbirth † Eden's Soul 490
Eden's Soul
12 rooms
... Spawns two item pedestals then is consumed. Begins with no charges.

Passive Collectibles

Name ID Icon Quote Description
Blood of the Martyr 7 Blood of the Martyr DMG up Increases Damage by 1, and turns Isaac's tears into blood tears.
The Body 334 The Body I feel all Adds 3 Heart Containers.
Celtic Cross 162 Celtic Cross You feel blessed Grants a chance to trigger the Book of Shadows Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Censer 387 Censer Peace be with you Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
Circle of Protection 423 Circle of Protection Protect me from myself Surrounds Isaac with a large white halo. Once per second, the halo deals Isaac's tear damage to enemies inside it. It may also convert enemy shots entering the halo into friendly purple homing tears.
Crown of Light 415 Crown of Light The untainted gain power +2 soul hearts. While Isaac has no damaged red heart containers, grants diamond tears that deal double damage and have increased range and reduced shot speed. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
Cube of Meat 73 Cube of Meat Gotta meat 'em all! Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, it makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
Dead Dove 185 Dead Dove Flight + spectral tears Grants spectral tears and flight.
Godhead 331 Godhead God tears Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
Guardian Angel 112 Guardian Angel Extra protection Spawns an orbital familiar that blocks enemy projectiles, deals contact damage to enemies, and increases the speed of all orbital familiars.
Holy Grail 184 Holy Grail Flight + HP up Grants flight and one Red Heart container.
Holy Mantle 313 Holy Mantle Holy shield Upon entering a room, grants a shield that negates the first damage taken.
Holy Water 178 Holy Water Splash! Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep. The bottle is reformed upon entering a different room.
Immaculate Conception 413 Immaculate Conception Feed them love Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Jesus Juice 197 Jesus Juice Damage + range up Increases Damage and Range.
The Mind 333 The Mind I know all Grants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.
Mitre 173 Mitre You Feel Blessed Grants a chance of converting any red hearts pickups into soul hearts instead.
Purity 407 Purity Aura stat boost Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range.
Rosary 72 Rosary Faith up Adds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.
Sacred Heart 182 Sacred Heart Homing shots + DMG up Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
Seraphim 390 Seraphim Sworn friend An angel familiar which follows Isaac and fires homing tears which deal 10 damage and have -25% shot speed.
Spear of Destiny 400 Spear of Destiny Your destiny In addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown but deals damage while it is in contact with an enemy.
Stigmata 138 Stigmata DMG + HP up Increases damage, and adds 1 heart container.
Sworn Protector 363 Sworn Protector Protective friend An orbital angel which does 7 contact damage per tick and attracts and blocks enemy shots. Upon blocking 10 shots in a room it drops an Eternal Heart.
The Soul 335 The Soul I am all Grants two soul hearts. Isaac gains a pulsing aura that repels enemies and projectiles.
Trinity Shield 243 Trinity Shield "You feel guarded" Isaac gains a shield that protects him from enemy shots.
Added in Afterbirth † 7 Seals 526 7 Seals Lil harbingers! Grants a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
Added in Afterbirth † Angelic Prism 528 Angelic Prism Eclipsed by the moon Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Added in Afterbirth † Eucharist 499 Eucharist Peace be with you An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after The Womb The Womb II/Utero Utero II.
Added in Afterbirth † Glyph of Balance 464 Glyph of Balance A gift from above Grants 2 Soul Hearts and modifies drops from Champion monsters based on certain conditions.
Added in Afterbirth † Trisagion 533 Trisagion Smite thy enemy Damage down. Tears are replaced with piercing white blasts of light that can damage the same enemy multiple times.


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