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Font TeamMeat B.pngFont TeamMeat F.pngFont TeamMeat F.pngFont TeamMeat S.pngFont TeamMeat emark.png
Item icon
Item altar
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Character appearance
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Shop Shop
Greed mode only Shop Shop
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Added in  Afterbirth(page 3, column 3, row 1)
Removed in Afterbirth(page 3, column 3, row 5)

BFFS! is a passive item.

Effects[edit | edit source]

  • Increases the size and doubles damage of familiars that deal damage through tears and contact damage.
    • Other familiars can be affected in non obvious ways.

Notes[edit | edit source]

  • Familiars that do not deal damage only obtain a cosmetic increase in size but do not gain any benefit. For certain pickup-generating familiars, it increases the frequency that they drop pickups.
  • Familiars summoned by a trinket or by Monster Manual Monster ManualMonster Manual Icon.png3 roomsSummons a random familiar for the current room. Can summon familiars not yet unlocked. are also affected by this item.
  • Only increases the size of Rotten Baby Rotten BabyRotten Baby Icon.pngA familiar that spawns blue flies., as it is not the item itself which does damage, but rather the blue flies it spawns.
    • The blue flies benefit from Hive Mind instead.

Interactions[edit | edit source]

  • BBF BBFBBF Icon.pngSpawns a familiar that flies around the room in a manner similar to the Boom Fly and explodes on contact with an enemy. Respawns after ten seconds./Bob's Brain Bob's BrainBob's Brain Icon.pngSpawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.: Increases damage the explosion inflicts by 35.
  • Added in  AfterbirthEvil Eye Evil EyeEvil Eye Afterbirth Icon.pngWhile firing tears, Isaac has a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac. The eye will be destroyed if it comes into contact with an enemy or obstacle.: The eyes are not treated as familiars and therefore will not synergize with BFFS!
  • Isaac's Heart Isaac's HeartIsaac's Heart Icon.pngIsaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.: Increases the size of the heart's hitbox, making it easier to get hit.

Synergies[edit | edit source]

  • Added in Afterbirth †Acid Baby Acid BabyAcid Baby Icon.pngSpawns a familiar that drops random pills every 2 rooms cleared. Upon using a pill, all enemies in the room are poisoned.: Increases the frequency of pill drops.
  • Added in Afterbirth †Angelic Prism Angelic PrismAngelic Prism Icon.pngGrants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.: Increases size of the prism's hitbox making it easier to hit.
  • Bomb Bag Bomb BagBomb Bag Icon.pngIsaac is followed by a small bag that drops a Bomb, 1+1 Free, or a Troll Bomb every 3 rooms.: Increases the frequency of bomb drops.
  • Added in Afterbirth †Brown Nugget Brown NuggetBrown Nugget Icon.png7 secondsSpawns a stationary fly familiar that fires tears at nearby enemies.: Flies are larger, but do not deal increased damage.
  • Added in  AfterbirthBumbo BumboBumbo Icon.pngSpawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.: Doubles Bumbo's damage and increases the chance for him to drop pickups.
  • Added in  AfterbirthIncubus IncubusIncubus Icon.pngA demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects.: Incubus deals double Isaac's damage instead of copying it. Effectively doubles Lilith's damage.
  • Juicy Sack Juicy SackJuicy Sack Icon.pngA familiar that follows behind Isaac. It drips a trail of creep, which slows enemies, and spawns 1-2 blue spiders after each room.: Spawns an extra blue spider.
  • Added in  AfterbirthLil Chest Lil ChestLil Chest Icon.pngSpawns a chest familiar that follows Isaac and drops a random pickup every few rooms.: Increases the chance to spawn a pickup or trinket by 25%.
  • Little C.H.A.D. Little C.H.A.D.Little C.H.A.D. Icon.pngA familiar who will drop a half red heart every 2 rooms.: Increases the frequency of heart drops.
  • Mystery Sack Mystery SackMystery Sack Icon.pngSpawns a familiar that follows Isaac around and has a chance to drop a heart, coin, bomb, or key after clearing a room.: Increases the frequency of pickup drops.
  • Orbitals: Doubles the damage and increases the size of all orbitals, both increasing their offensive and defensive properties.
  • The Relic The RelicThe Relic Icon.pngIsaac is followed by a small blue cross that will drop a Soul Heart every 4 rooms.: Increases the frequency of soul heart drops.
  • Added in  AfterbirthRune Bag Rune BagRune Bag Icon.pngA bag that follows Isaac and drops a random rune every 3 rooms.: Increases the frequency of rune drops.
  • Sack of Pennies Sack of PenniesSack of Pennies Icon.pngIsaac is followed by a small bag that drops a coin every 2 rooms.: Increases the frequency of coin drops.
  • Added in Afterbirth †Sack of Sacks Sack of SacksSack of Sacks Icon.pngSpawns a sack familiar that has a chance to drop a sack upon clearing a room.: Increases the frequency of sack drops.
  • Added in  AfterbirthSpider Mod Spider ModSpider Mod Icon.pngDisplays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.: Increases the chance for Spider Mod to spawn a battery or blue spider upon clearing a room from 10% to 12.5%.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • BFF stands for Best Friends Forever.
  • This item can be considered a buddy version of the Magic Mushroom Magic MushroomMagic Mushroom Icon.pngIncreases all stats and enlargens Isaac..
  • This item is used in challenge #19 (The Family Man).

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