Blood may refer to:
Mechanics
Some things that aren't items that reference Blood
Challenges
Bloody Mary: A Bethany challenge that starts with some blood related items
Environment
- Blood Donation Machine, a machine which depletes half of a Red Heart container in exchange for dropping coins.
- Red Creep, which represents blood.
Blood in title
The word "blood" appears in the title of the item.
Collectibles
Activated
Blood Rights, damages entire room at the cost of depleting a full Red Heart container.
Passive
Blood Bag, grants increased health.
Blood Clot, grants increased damage and range.
Blood of the Martyr, grants increased damage and turns Isaac's tears into blood tears.- Bloody Lust, after taking damage, grants increased damage for the floor.
- Lusty Blood, increases damage by 0.5 up to 10 times in the current room each time a monster is defeated.
- Bloodshot Eye, Spawns an orbital familiar that deals 30 damage per second and fires a randomly angled tear every 2 seconds.
- Pickup quote states, "Bloody friend"
- Blood Bombs, Bombs leave behind damaging red creep. Isaac can place bombs at the cost of half a heart if he doesn't have any. Pickup quote states,
- "Bloody blast + HP up"
- Blood Oath, Stabs Isaac at the beginning of each floor, draining his red hearts. Increases damage and speed for the floor based on the amount drained.
- Blood Puppy, Spawns a familiar that chases enemies. After killing enough enemies, it becomes more powerful and drops red hearts after killing enemies, but will also try to hurt Isaac. Attacking it returns it to normal.
- Bloody Gust, When Isaac takes damage, he gains speed and tears for the rest of the floor.
- ===Trinkets ===
- Bloody Penny, when a coin is collected, grants a 50% chance to drop a half Red Heart.
- Bloody Crown, Treasure Rooms now appear in chapter 4.
- Pickup quote states, "Drips with blood..."
Blood in item pickup quote
The word blood appears in the pickup quote of the item.
Activated
- IV Bag, drops Pennies at the cost of depleting half of a Red Heart container.
- Pickup quote states, "Portable blood bank."
- Sharp Straw, Damages all enemies in the room, has a chance to drop a half soul heart if an enemy is hit.
- Pickup quote states, "More blood!"
Passive
- Anemic, after taking damage, grants a trail of red creep for the room.
- Pickup quote states, "Toxic blood."
- Anemia is a decrease in the blood's ability to carry oxygen.
- Brimstone, Replaces Isaac's tears with a charged laser.
- Pickup quote states, "Blood laser barrage"
- Leech , Spawns a leech familiar that chases enemies, dealing ~3 damage per second. Heals a Half Red Heart whenever Leech kills an enemy.
- Pickup quote states, "Blood sucker."
- Headless Baby, Spawns a familiar that follows Isaac, leaving blood creep on the ground.
- Pickup quote states, "Bloody friend."
- Bloodshot Eye, Spawns an orbital familiar that deals 30 damage per second and fires a randomly angled tear every 2 seconds.
- Pickup quote states, "Bloody friend."
- Jumper Cables, Grants an active item charge every 15 enemies killed.
- Pickup quote states, "Bloody recharge"
- Shard of Glass Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
- Pickup quote states, "Blood and guts"
- Taking damage causes Isaac to bleed, spraying a volley of blood in the direction he fires. The Bleeding will eventually damage him, but it can be stopped by picking up a Red Heart.
- A Pound of Flesh, Devil deals now cost coins, shop items now cost health, and consumables in shops are surrounded by spikes.
- Pickup quote states, "Blood money"
gain 5 range, and leave a trail of damaging red creep for the current room.
- Hungry Soul, Enemies have a chance to spawn ghosts on death, which chase and deal contact damage to enemies and explode after a short time.
- Pickup quote states, "Out for Blood "
- Hypercoagulation, After Isaac takes damage from an enemy or donates health, launches red hearts from Isaac that despawn after 1.5 seconds.
- Pickup quote states, "Thick Blooded"
- Hypercoagulation is a medical condition that causes blood clots to spontaneously form in a person’s blood vessels and prevents them from dissolving properly.
- Vengeful Spirit After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots.
- Pickup quote states, "Hot blooded"
Trinkets
- Bloody Crown, Treasure Rooms now spawn in chapter 4.
- Pickup quote states, "Drips with blood..."
Employs blood creep/tears
When the item is used, it spawns red tears and/or red creep, to show blood.
Activated
- The Book of Belial, grants a damage up for the current room and turns Isaac's tears blood Red.
- Scissors, Turns Isaac's head into a stationary familiar for the current room which fires tears automatically.
- causes Isaac's body to shoot a controllable fountain of blood shots.
- Glass Cannon, Fires a high-damage piercing spectral tear, but lowers Isaac's health to half a heart.
- Fires a high-damage piercing spectral tear. If Isaac takes damage while holding this, he takes extra damage, leaves behind blood red creep behind him, and it becomes the Broken Glass Cannon.
Passive
- Headless Baby, Spawns a familiar that follows Isaac, leaving blood creep on the ground.
- Pickup quote states, "Bloody friend."
- Kidney Stone, Isaac's tears turn blood red, and Randomly while firing tears, Isaac will stop firing and turn red himself, where he will charge and release a lot of 'tears' in one go.
- Lead Pencil, After every 15 tears fired, Isaac will fire a high-damage cluster of blood red tears.
- Pickup quote states, " He's a bleeder!"
- Haemolacria,Tears are now Red and fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
- Haemolacria is a real condition that causes people to cry blood.
- Hemoptysis, Double-tapping a fire button causes Isaac to sneeze blood, dealing damage to enemies in front of him.
- Hemoptysis is the medical term for coughing up blood.
- Akeldama, While in an uncleared room, Isaac forms a trail of bloody tears that drags behind him, bursting and dealing damage upon contact with enemies.
- Akeldama means 'field of blood' in Aramaic, and the item references the field that Judas spilled his guts out on
- Isaac's Heart Isaac himself is now immune to all damage, and a heart familiar follows him. If the heart is hurt, Isaac is hurt.
- The heart charges up as Isaac shoots, firing 8 blood shots, knocking back enemies, and leaving a puddle of Blood creep when released.
Bleeding
When losing blood, you bleed. here are the few items that reference bleeding.
- Backstabber,Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac.
- Mom's Razor, Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time.
- Lead Pencil, After every 15 tears fired, Isaac will fire a high-damage cluster of blood red tears.
- Pickup quote states, " He's a bleeder!"
- Shard of Glass Upon taking damage, Isaac has a chance to drop a full red heart,gain 5 range, and leave a trail of damaging red creep for the current room.
- Pickup quote states, "Blood and guts"
- Taking damage causes Isaac to bleed, spraying a volley of blood in the direction he fires. Bleeding will eventually damage him, but it can be stopped by picking up a Red Heart.
- Blood Oath, Stabs Isaac at the beginning of each floor, draining his red hearts. Increases damage and speed for the floor based on the amount drained.
- Pickup quote states, " Bleed me dry"
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This disambiguation page lists articles associated with the same title. If an internal link referred you here, you may wish to change the link to point directly to the intended article. |
 The Binding of Isaac: Rebirth
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