Boss (Afterbirth+ Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
Added in Afterbirth Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Added in Afterbirth Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Added in Afterbirth † Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Added in Afterbirth † Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

The Boss Pool is the pool of items that are dropped by bosses and can be found in the Boss Challenge Room.


Name ID Icon Quote Description
<3 15 <3 HP up Grants Isaac one red heart container and fully restores Isaac's health.
A Snack 346 A Snack HP up Grants one full red heart container.
Added in Afterbirth † Belly Button 458 Belly Button What's in there? Drops a random trinket. Grants a second trinket slot.
The Belt 28 The Belt Speed up Increases speed by 0.3.
Added in Afterbirth Binky 438 Binky Memories... Tears up, adds 1 soul heart, and decreases Isaac's size.
Blood Clot 254 Blood Clot DMG + range up Increases damage by 1 and range by 5 for tears fired from the left eye.
Blue Cap 342 Blue Cap HP + tears up + shot speed down Grants 1 heart container and increases tears, but decreases shot speed.
Box 198 Box Stuff Spawns 1 of each (non-collectible) item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.
Breakfast 25 Breakfast HP up Grants Isaac one full red heart container.
Caffeine Pill 340 Caffeine Pill Speed up + size down Increases speed and reduces character size. Also gives a random pill.
Cat-O-Nine-Tails 165 Cat-O-Nine-Tails Shot speed + damage up Increases Shot Speed and damage.
Added in Afterbirth Crack Jacks 354 Crack Jacks Don't swallow the prize! Adds one heart container and drops a random trinket.
Added in Afterbirth † Dad's Lost Coin 455 Dad's Lost Coin I remember this... Increases range by 1.5. Drops a lucky penny. Other Effects Unknown
Dessert 24 Dessert HP Up Grants Isaac one full red heart container.
Dinner 23 Dinner HP Up Adds 1 heart container.
Added in Afterbirth † Divorce Papers 547 Divorce Papers Tears up + you feel empty Spawns a Mysterious Paper, increases tears, and grants a bone heart.
Experimental Treatment 240 Experimental Treatment All stats up, then shuffled Randomly increases and decreases some of the character's stats. There will always be at least one stat increase and one decrease and the same stats can be increased/decreased multiple times.
Growth Hormones 70 Growth Hormones Speed + DMG up Increases damage by 1 and speed by 0.4.
The Halo 101 The Halo All stats up Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
Jesus Juice 197 Jesus Juice Damage + range up Increases Damage and Range.
Latch Key 343 Latch Key Luck up Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Little Steven 100 Little Steven Psychic friend Spawns a familiar that follows Isaac around and fires homing tears.
Lunch 22 Lunch HP Up Adds 1 heart container.
MEAT! 193 MEAT! DMG + HP up Adds a heart container and increases damage.
Magic 8 Ball 194 Magic 8 Ball Shot speed up Increases Shot Speed, and drops a Tarot Card when picked up.
Magic Mushroom 12 Magic Mushroom All Stats Up! Increases all stats and enlargens Isaac.
Magic Scab 253 Magic Scab HP + Luck up Increases luck and HP by 1.
Added in Afterbirth † Marbles 538 Marbles Choking hazard Spawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.
Added in Afterbirth † Marrow 541 Marrow HP up? Grants one bone heart and spawns three red heart pickups.
Match Book 344 Match Book Evil up Grants Isaac 1 Black Heart and 3 bombs. Can also give troll bombs.
Added in Afterbirth † Moldy Bread 456 Moldy Bread Midnight snack! Grants one full red heart container.
Mom's Coin Purse 195 Mom's Coin Purse What's all this...? Spawns 4 random pills around Isaac.
Mom's Heels 30 Mom's Heels Range up Increases range.
Mom's Lipstick 31 Mom's Lipstick Range up Increases range and shot height.
Added in Afterbirth Mom's Pearls 355 Mom's Pearls Range + luck up +1.25 Range Up. +0.5 Tear Height. +1 Luck Up.
Mom's Underwear 29 Mom's Underwear Range up Increases range.
Added in Afterbirth Mr. Dolly 370 Mr. Dolly Range + tears up Tears and Range up. Spawns 3 random types of hearts on the floor when picked up.
Old Bandage 219 Old Bandage HP up Adds one empty heart container. Whenever Isaac takes damage there's a chance that a Red Heart may drop.
Added in Afterbirth PJs 428 PJs You feel cozy Grants four soul hearts and fully restores Isaac's red health.
Pageant Boy 141 Pageant Boy Ultimate grand supreme Spawns several coins around Isaac.
Pentagram 51 Pentagram DMG up Increases damage and increases the chance for a Devil or Angel Room to appear.
Placenta 218 Placenta HP up + regen Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Added in Afterbirth † Polydactyly 454 Polydactyly Hold me! Allows Isaac to carry two cards, pills, or any combination of both at the same time. Drops a random card or pill.
Roid Rage 14 Roid Rage Speed and range up Increases speed by 0.6, range by 5.25, and tear height by 0.5.
Rotten Meat 26 Rotten Meat HP up Adds one heart container.
Safety Pin 339 Safety Pin Evil + range + shot speed up Increases range and shot speed, while adding 1 Black Heart.
Screw 255 Screw Tears and shot speed up. +0.5 tears up, +0.2 shot speed up.
Speed Ball 143 Speed Ball Speed + shot speed up Increases speed by 0.3 and shot speed by 20%.
Squeezy 196 Squeezy Tears up Increases tears by 0.4, and spawns 2 Soul Hearts pickups.
Stem Cells 176 Stem Cells HP up Adds one filled heart container and increases Shot Speed.
Super Bandage 92 Super Bandage +2 hearts Grants one Heart Container and gives 2 Soul Hearts.
Synthoil 345 Synthoil DMG up + range Increases damage by 1, range by 5.25, and tear height by 0.5.
Toothpicks 183 Toothpicks Tears + shot speed up +0.7 tears, +16% shot speed.
Torn Photo 341 Torn Photo Tears + shot speed up Tears + Shot speed up.
Wire Coat Hanger 32 Wire Coat Hanger Tears up Increases Tears by 0.7.


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