Boss (Afterbirth Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
DLC Indicator.png Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
DLC Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Afterbirth† Indicator.png Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Afterbirth† Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

The Boss Pool is the pool of items that are dropped by bosses and can be found in the Boss Challenge Room.


Name ID Icon Quote Description
<3 15 Less Than Three Icon.png HP up Increases available heart containers by 1 and restores all health.
A Snack 346 A Snack Icon.png HP up Adds 1 heart container.
Binky DLC Indicator.png 438 Binky Icon.png Memories... Tears up, adds 1 soul heart, and decreases Isaac's size.
Blood Clot 254 Blood Clot Icon.png DMG + range up Increases damage by 1 and range by 5 for tears fired from the left eye.
Blue Cap 342 Blue Cap Icon.png HP + tears up + shot speed down Grants 1 heart container and increases tears, but decreases shot speed.
Box 198 Box Icon.png Stuff Spawns 1 of each (non-collectible) item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.
Breakfast 25 Breakfast Icon.png HP up Adds 1 heart container.
Caffeine Pill 340 Caffeine Pill Icon.png Speed up + size down Increases speed and reduces character size. Also gives a random pill.
Cat-O-Nine-Tails 165 Cat-O-Nine-Tails Icon.png Shot speed + damage up Increases Shot Speed and damage.
Crack Jacks DLC Indicator.png 354 Crack Jacks Icon.png Don't swallow the prize! Adds one heart container and drops a random trinket.
Dessert 24 Dessert Icon.png HP Up Adds 1 heart container.
Dinner 23 Dinner Icon.png HP Up Adds 1 heart container.
Experimental Treatment 240 Experimental Treatment Icon.png All stats up, then shuffled Randomly increases and decreases some of the character's stats. There will always be at least one stat increase and one decrease and the same stats can be increased/decreased multiple times.
Growth Hormones 70 Growth Hormones Icon.png Speed + DMG up Increases damage by 1 and speed by 0.4.
Jesus Juice 197 Jesus Juice Icon.png Damage + range up Increases Damage and Range.
Latch Key 343 Latch Key Icon.png Luck up Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Little Steven 100 Little Steven Icon.png Psychic friend Spawns a familiar that follows Isaac around and fires homing tears.
Lunch 22 Lunch Icon.png HP Up Adds 1 heart container.
MEAT! 193 MEAT! Icon.png DMG + HP up Adds a heart container and increases damage.
Magic 8 Ball 194 Magic 8 Ball Icon.png Shot speed up Increases Shot Speed, and drops a Tarot Card when picked up.
Magic Mushroom 12 Magic Mushroom Icon.png All Stats Up! Increases all stats and enlargens Isaac.
Magic Scab 253 Magic Scab Icon.png HP + Luck up Increases luck and HP by 1.
Match Book 344 Match Book Icon.png Evil up Grants Isaac 1 Black Heart and 3 bombs. Can also give troll bombs.
Mom's Coin Purse 195 Mom's Coin Purse Icon.png What's all this...? Spawns 4 random pills around Isaac.
Mom's Heels 30 Mom's Heels Icon.png Range up Increases range.
Mom's Lipstick 31 Mom's Lipstick Icon.png Range up Increases range and shot height.
Mom's Pearls DLC Indicator.png 355 Mom's Pearls Icon.png Range + luck up +1.25 Range Up. +0.5 Tear Height. +1 Luck Up.
Mom's Underwear 29 Mom's Underwear Icon.png Range up Increases range.
Mr. Dolly DLC Indicator.png 370 Mr. Dolly Icon.png Range + tears up Tears and Range up. Spawns 3 random types of hearts on the floor when picked up.
Old Bandage 219 Old Bandage Icon.png HP up Adds one empty heart container. Whenever Isaac takes damage there's a chance that a Red Heart may drop.
PJs DLC Indicator.png 428 PJs Icon.png You feel cozy Adds 4 Soul Hearts and fully restores Isaac's red health.
Pageant Boy 141 Pageant Boy Icon.png Ultimate grand supreme Spawns several coins around Isaac.
Pentagram 51 Pentagram Icon.png DMG up Increases damage and increases the chance for a Devil or Angel Room to appear.
Placenta 218 Placenta Icon.png HP up + regen Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Roid Rage 14 Roid Rage Icon.png Speed and range up Increases speed by 0.6, range by 5.25, and tear height by 0.5.
Rotten Meat 26 Rotten Meat Icon.png HP up Adds one heart container.
Safety Pin 339 Safety Pin Icon.png Evil + range + shot speed up Increases range and shot speed, while adding 1 Black Heart.
Screw 255 Screw Icon.png Tears + shot speed up Tears and shot speed up.
Speed Ball 143 Speed Ball Icon.png Speed + shot speed up Increases speed by 0.3 and shot speed by 20%.
Squeezy 196 Squeezy Icon.png Tears up Increases tears by 0.4, and spawns 2 Soul Hearts pickups.
Stem Cells 176 Stem Cells Icon.png HP up Adds one filled heart container and increases Shot Speed.
Super Bandage 92 Super Bandage Icon.png +2 hearts Grants one Heart Container and gives 2 Soul Hearts.
Synthoil 345 Synthoil Icon.png DMG up + range Increases damage by 1, range by 5.25, and tear height by 0.5.
The Belt 28 The Belt Icon.png Speed up Increases speed by 0.3.
The Halo 101 The Halo Icon.png All stats up Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
Toothpicks 183 Toothpicks Icon.png Tears + shot speed up Increases tears and shot speed.
Torn Photo 341 Torn Photo Icon.png Tears + shot speed up Tears + Shot speed up.
Wire Coat Hanger 32 Wire Coat Hanger Icon.png Tears up Increases Tears by 0.7.
Wooden Spoon 27 Wooden Spoon Icon.png Speed up Increases speed by 0.3.