Binding of Isaac: Rebirth Wiki
(Rag Mega Location (I'll Try To Add Bosses To The Dank Depths Section Soon If Possible))
(Added Locations for Bosses for the 3rd Floor. May Try To Do 4th Floor If Possible (Oh Boy...))
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===[[Dank Depths]] {{dlc|a}}===
 
===[[Dank Depths]] {{dlc|a}}===
 
{| style="width:70%; align:left padding-right:2em"
 
{| style="width:70%; align:left padding-right:2em"
 
| style="text-align: center; border: none" |[[File:Boss_Monstro_II.png|center|link=Monstro II]]
 
| style="text-align: center; border: none" |[[File:Boss_Gish.png|center|link=Gish]]
 
| style="text-align: center; border: none" |[[File:Boss_The_Adversary.png|center|link=The Adversary]]
 
| style="text-align: center; border: none" |[[File:Boss_Loki.png|center|link=Loki]]
  +
| style="text-align: center; border: none" |[[File:Boss_War.png|center|link=War]]
 
| style="text-align: center; border: none" |[[File:Boss_Brownie.png|center|link=Brownie]]
 
| style="text-align: center; border: none" |[[File:Boss_Brownie.png|center|link=Brownie]]
  +
| style="text-align: center; border: none" |[[File:Boss Sisters Vis.png|center|link=Sisters Vis]]
 
|-
 
|-
  +
| style="text-align: center; border: none" |[[Monstro II]]
  +
| style="text-align: center; border: none" |[[Gish]]
  +
| style="text-align: center; border: none" |[[The Adversary]]
  +
| style="text-align: center; border: none" |[[Loki]]
  +
| style="text-align: center; border: none" |[[War]]
 
| style="text-align: center; border: none" |[[Brownie]] {{dlc|a}}
 
| style="text-align: center; border: none" |[[Brownie]] {{dlc|a}}
  +
| style="text-align: center; border: none" |[[Sisters Vis]] {{dlc|a+}}
  +
 
|}
 
|}
 
===Floor 2===
 
===Floor 2===
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| style="text-align: center; border: none" |[[File:Boss_Mr._Fred.png|center|link=Mr. Fred]]
 
| style="text-align: center; border: none" |[[File:Boss_Mr._Fred.png|center|link=Mr. Fred]]
 
| style="text-align: center; border: none" |[[File:Boss_Scolex.png|center|link=Scolex]]
 
| style="text-align: center; border: none" |[[File:Boss_Scolex.png|center|link=Scolex]]
  +
| style="text-align: center; border: none" |[[File:Boss_Teratoma.png|center|link=Teratoma]]
 
|-
 
|-
 
| style="text-align: center; border: none" |[[Mr. Fred]]
 
| style="text-align: center; border: none" |[[Mr. Fred]]
 
| style="text-align: center; border: none" |[[Scolex]]
 
| style="text-align: center; border: none" |[[Scolex]]
  +
| style="text-align: center; border: none" |[[Teratoma]]
 
|}
 
|}
   
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{| style="width:70%; align:left padding-right:2em"
 
{| style="width:70%; align:left padding-right:2em"
 
| style="text-align: center; border: none" |[[File:Boss_Mama_Gurdy.png|center|link=Mama Gurdy]]
 
| style="text-align: center; border: none" |[[File:Boss_Mama_Gurdy.png|center|link=Mama Gurdy]]
| style="text-align: center; border: none" |[[File:Boss_Lokii.png|center|link=Lokii]]
 
 
|-
 
|-
 
| style="text-align: center; border: none" |[[Mama Gurdy]]
 
| style="text-align: center; border: none" |[[Mama Gurdy]]
| style="text-align: center; border: none" |[[Lokii]]
 
 
|}
 
|}
 
===The Womb and Utero===
 
===The Womb and Utero===
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| style="text-align: center; border: none" |[[File:Boss_Blastocyst.png|center|link=Blastocyst]]
 
| style="text-align: center; border: none" |[[File:Boss_Blastocyst.png|center|link=Blastocyst]]
 
| style="text-align: center; border: none" |[[File:Boss_The_Bloat.png|center|link=The Bloat]]
 
| style="text-align: center; border: none" |[[File:Boss_The_Bloat.png|center|link=The Bloat]]
| style="text-align: center; border: none" |[[File:Boss_Daddy_Long_Legs.png|center|link=Daddy_Long_Legs]]
+
| style="text-align: center; border: none" |[[File:Boss_Lokii.png|center|link=Lokii]]
 
|-
 
|-
 
| style="text-align: center; border: none" |[[Blastocyst]]
 
| style="text-align: center; border: none" |[[Blastocyst]]
 
| style="text-align: center; border: none" |[[The Bloat]]
 
| style="text-align: center; border: none" |[[The Bloat]]
 
| style="text-align: center; border: none" |[[Daddy Long Legs]]
 
| style="text-align: center; border: none" |[[Daddy Long Legs]]
  +
| style="text-align: center; border: none" |[[Lokii]]
  +
 
|}
 
|}
   
 
{| style="width:70%; align:left padding-right:2em"
 
{| style="width:70%; align:left padding-right:2em"
| style="text-align: center; border: none" |[[File:Boss_Teratoma.png|center|link=Teratoma]]
 
 
| style="text-align: center; border: none" |[[File:Boss_Triachnid.png|center|link=Triachnid]]
 
| style="text-align: center; border: none" |[[File:Boss_Triachnid.png|center|link=Triachnid]]
 
| style="text-align: center; border: none" |[[File:Boss_Death.png|center|link=Death (Boss)]]
 
| style="text-align: center; border: none" |[[File:Boss_Death.png|center|link=Death (Boss)]]
 
|-
 
|-
| style="text-align: center; border: none" |[[Teratoma]]
 
 
| style="text-align: center; border: none" |[[Triachnid]]
 
| style="text-align: center; border: none" |[[Triachnid]]
 
| style="text-align: center; border: none" |[[Death (Boss)|Death]]
 
| style="text-align: center; border: none" |[[Death (Boss)|Death]]

Revision as of 20:34, 6 June 2018

Bosses are very strong monsters found in boss rooms at the end of a floor. The boss at the end of the floor must be defeated in order to advance to the next floor. In later chapters, bosses are able to spawn as normal enemies. This starts in the caves, where the Gurglings are often encountered. The boss for a particular floor is chosen from the pool of bosses for the environment of the floor. Bosses may also spawn as champions, which can change various attributes such as health, damage, and attack pattern. Upon defeat, most bosses will drop an item from the boss item pool.

Bosses boast additional resistances to status effects. For example, fear occurs less often and the Night Light is unable to slow them down.

Additionally, some floors may spawn a room with a Mini-Boss.

In total, there are 72 bosses and 18 mini-bosses. 10 bosses were added in Afterbirth and 6 were added in Afterbirth †.

Chapter 1

The Basement

Boss Monstro Boss Gemini
Boss Larry Jr.
Monstro Gemini Larry Jr.
Boss Dingle
Boss Gurglings
Boss Steven
Dingle Gurglings Steven

The Cellar

Boss Pin
Boss Widow
Boss Blighted Ovum
Pin Widow Blighted Ovum
Boss Fistula
Boss Gurdy Jr.
Boss The Haunt
Fistula Gurdy Jr. The Haunt

The Basement and The Cellar

Boss The Duke of Flies
Boss Famine
Boss Rag Man
The Duke of Flies Famine Rag Man (except in Rebirth)
Boss Little Horn
Boss Dangle
Boss Turdlings
Little Horn (except in Rebirth) Dangle (except in Rebirth) Turdlings (except in Rebirth)

Burning Basement (except in Rebirth)

Boss Rag Man
Boss Little Horn
Boss Dangle
Rag Man (except in Rebirth) Little Horn (except in Rebirth) Dangle (except in Rebirth)
Boss Turdlings
Turdlings (except in Rebirth)

Chapter 2

The Caves

Boss Chub
Boss Gurdy
Boss Mega Maw
Chub Gurdy Mega Maw
Boss Mega Fatty
Boss C.H.A.D.
Mega Fatty C.H.A.D.

The Catacombs

Boss The Hollow
Boss The Husk
Boss Dark One
The Hollow The Husk Dark One
Boss Polycephalus
Boss Carrion Queen
Boss The Wretched
Polycephalus Carrion Queen The Wretched

The Caves and The Catacombs

Boss Peep
Boss Gurdy Jr.
Boss Pestilence
Peep Gurdy Jr. Pestilence
Boss The Frail
Boss The Stain
Boss The Forsaken
The Frail (except in Rebirth) The Stain (except in Rebirth) The Forsaken (except in Rebirth)
Boss Big Horn
Boss Rag Mega
Big Horn (in Afterbirth † and Repentance) Rag Mega (in Afterbirth † and Repentance)

Double Trouble

Boss Dingle
Boss The Duke of Flies
Boss Gemini
(Double Trouble)

Dingle

(Double Trouble)

The Duke of Flies

(Double Trouble)

Gemini

Boss Widow
Boss Pin
Boss Polycephalus
(Double Trouble)

Widow

(Double Trouble)

Pin

(Double Trouble)

Polycephalus

Boss Larry Jr.
Boss Blighted Ovum
Boss Monstro
(Double Trouble)

Larry Jr.

(Double Trouble)

Blighted Ovum

(Double Trouble)

Monstro

Flooded Caves (except in Rebirth)

Boss The Frail
Boss The Stain
Boss The Forsaken
The Frail (except in Rebirth) The Stain (except in Rebirth) The Forsaken (except in Rebirth)
Boss Big Horn
Boss Rag Mega
Big Horn (in Afterbirth † and Repentance) Rag Mega (in Afterbirth † and Repentance)

Chapter 3

Floor 1

The Depths

Boss The Cage
Boss Monstro II
Boss The Gate
Boss Gish
The Cage Monstro II The Gate Gish

Necropolis

Boss The Adversary
Boss The Bloat
Boss Mask of Infamy
The Adversary The Bloat Mask of Infamy


The Depths and Necropolis

Boss Loki
Boss War
Boss Brownie
Loki War Brownie (except in Rebirth)
Boss Sisters Vis
Sisters Vis (in Afterbirth † and Repentance)

Double Trouble

Boss Gurdy Jr.
The Haunt
Boss The Wretched
Boss The Husk
(Double Trouble)

Gurdy Jr.

(Double Trouble)

The Haunt

(Double Trouble)

The Wretched

(Double Trouble)

The Husk

Boss Peep
Boss Mega Fatty
Boss Dark One
(Double Trouble)

Peep

(Double Trouble)

Mega Fatty

(Double Trouble)

Dark One

Boss Mega Maw
Boss Larry Jr.
Boss Blighted Ovum
(Double Trouble)

Mega Maw

(Double Trouble)

Larry Jr.

(Double Trouble)

Blighted Ovum

Dank Depths (except in Rebirth)

Boss Monstro II
Boss Gish
Boss The Adversary
Boss Loki
Boss War
Boss Brownie
Boss Sisters Vis
Monstro II Gish The Adversary Loki War Brownie (except in Rebirth) Sisters Vis (in Afterbirth † and Repentance)

Floor 2

The Depths, Necropolis and Dank Depths

Boss Mom
Mom

Chapter 4

Floor 1

The Womb

Boss Mr. Fred
Boss Scolex
Boss Teratoma
Mr. Fred Scolex Teratoma

Utero

Boss Mama Gurdy
Mama Gurdy

The Womb and Utero

Boss Blastocyst
Boss The Bloat
Boss Lokii
Blastocyst The Bloat Daddy Long Legs Lokii
Boss Triachnid
Boss Death
Triachnid Death
Boss Conquest
Conquest

Double Trouble

Boss The Cage
Boss Gurdy
Boss The Fallen
Boss The Gate
Boss Loki
(Double Trouble)

The Cage

(Double Trouble)

Gurdy

(Double Trouble)

The Fallen

(Double Trouble)

The Gate

(Double Trouble)

Loki

Scarred Womb

Boss The Matriarch
The Matriarch (in Afterbirth † and Repentance)

Floor 2

The Womb, Utero and Scarred Womb

Boss Mom's Heart
Boss It Lives
Mom's Heart It Lives

Blue Womb (except in Rebirth)

Boss Hush
Hush (except in Rebirth)


The Void (in Afterbirth † and Repentance)

Boss Delirium
Delirium (in Afterbirth † and Repentance)

Chapter 5

Sheol

Boss Satan
Satan

The Cathedral

Isaac

Chapter 6

The Chest

???
???

Dark Room

Boss The Lamb
The Lamb

Golden Door Boss

Boss Mega Satan
Mega Satan

Universal

Universal Bosses are those which may appear at the end of floors 1-5 and 7, replacing a boss from the pool for that environment.

Boss The Fallen
The Fallen The Headless Horseman

Devil and Angel Room

Devil Room

Boss Krampus
Krampus

Angel Room

Boss Angel
Boss Angel2
Uriel Gabriel

Seven Deadly Sins and Others

Seven Deadly Sins

The Seven Deadly Sins are mini-bosses that can be encountered on any floor, and will appear on post-Womb/Utero floors as regular enemies. Unlike with regular bosses, there is no special door leading to a mini-boss room, meaning that there is no way to tell whether a room is inhabited by a mini-boss unless the player is in possession of an item that reveals map icons such as Compass or a Map item. Once in a mini-boss room, the player cannot escape through means of bombing the door, as it will be boarded off.

Each of the Sins has specific drops, that are consumables or a pedestal item (less frequently).
In a room containing multiple Sins, only the last one will drop something, allowing you to choose what drop you want by killing a certain mini-boss last.

All them are based on the Seven Deadly Sins.

Boss Gluttony
Boss Wrath
Envy Gluttony Wrath
Boss Pride
Boss Lust
Boss Greed
Pride Lust Greed
Boss Sloth
Sloth

These monsters can also spawn as much stronger alternatives, known as the Seven Super Deadly Sins.

Boss Super Envy
Boss Super Gluttony
Boss Super Wrath
Super Envy Super Gluttony Super Wrath
Boss Super Pride
Boss Super Lust
Boss Super Greed
Super Pride Super Lust Super Greed
Boss Super Sloth
Super Sloth

There is also an Ultra variant of both Pride and Greed. Ultra Pride resembles Edmund and Florian, while Ultra Greed serves as the final boss for Greed Mode.

Boss Ultra Pride
Ultra Pride

Greed Mode (except in Rebirth)

Greed Mode

Boss Ultra Greed
Ultra Greed (except in Rebirth)

Greedier Mode

Boss Ultra Greedier
Ultra Greedier (in Afterbirth † and Repentance)

All Mini-Bosses

The Seven Deadly Sins

Boss Gluttony
Boss Wrath
Envy Gluttony Wrath
Boss Pride
Boss Lust
Boss Greed
Pride Lust Greed
Boss Sloth
Sloth

The Seven Super Deadly Sins

Boss Super Envy
Boss Super Gluttony
Boss Super Wrath
Super Envy Super Gluttony Super Wrath
Boss Super Pride
Boss Super Lust
Boss Super Greed
Super Pride Super Lust Super Greed
Boss Super Sloth
Super Sloth

Ultra Pride

Boss Ultra Pride
Ultra Pride

Krampus

Boss Krampus
Krampus

Angels

Boss Angel
Boss Angel2
Uriel Gabriel

All Bosses

Boss Monstro Boss Gemini
Boss Larry Jr.
Monstro Gemini Larry Jr.
Boss Dingle
Boss Gurglings
Boss Steven
Dingle Gurglings Steven
Boss Pin
Boss Widow
Boss Blighted Ovum
Pin Widow Blighted Ovum
Boss Fistula
Boss Gurdy Jr.
Boss The Haunt
Fistula Gurdy Jr. The Haunt
Boss The Duke of Flies
Boss Rag Man
Boss Little Horn
The Duke of Flies Rag Man (except in Rebirth) Little Horn (except in Rebirth)
Boss Dangle
Boss Turdlings
Boss Chub
Dangle (except in Rebirth) Turdlings (except in Rebirth) Chub
Boss Gurdy
Boss Mega Maw
Boss C.H.A.D.
Gurdy Mega Maw C.H.A.D.
Boss Mega Fatty
Boss The Hollow
Boss The Husk
Mega Fatty The Hollow The Husk
Boss Dark One
Boss Polycephalus
Boss The Frail
Dark One Polycephalus The Frail (except in Rebirth)
Boss The Stain
Boss The Forsaken
Boss Carrion Queen
The Stain (except in Rebirth) The Forsaken (except in Rebirth) Carrion Queen
Boss The Wretched
Boss Peep
Boss Big Horn
The Wretched Peep Big Horn (in Afterbirth † and Repentance)
Boss Rag Mega
Boss The Cage
Boss Loki
Rag Mega (in Afterbirth † and Repentance) The Cage Loki
Boss Monstro II
Boss Gish
Boss The Gate
Monstro II Gish The Gate
Boss The Adversary
Boss The Bloat
Boss Mask of Infamy
The Adversary The Bloat Mask of Infamy
Boss Brownie
Boss Sisters Vis
Boss Mr. Fred
Brownie (except in Rebirth) Sisters Vis (in Afterbirth † and Repentance) Mr. Fred
Boss Scolex
Boss Mama Gurdy
Boss Lokii
Scolex Mama Gurdy Lokii
Boss Blastocyst
Boss The Matriarch
Boss Teratoma
Blastocyst The Matriarch (in Afterbirth † and Repentance) Teratoma
Boss Daddy Long Legs
Boss Triachnid
Boss The Fallen
Daddy Long Legs Triachnid The Fallen

The Harbingers

Boss Famine
Boss Pestilence
Boss War
Famine Pestilence War
Boss Death
Boss Conquest
Death Conquest The Headless Horseman

Final Bosses

Boss Mom
Boss Mom's Heart
Boss It Lives
Mom Mom's Heart It Lives
Boss Satan
Satan Isaac
Boss The Lamb
???
The Lamb ???
Boss Hush
Boss Mega Satan
Hush (except in Rebirth) Mega Satan
Boss Ultra Greed
Boss Ultra Greedier
Ultra Greed (except in Rebirth) Ultra Greedier (in Afterbirth † and Repentance)
Boss Delirium
Delirium (in Afterbirth † and Repentance)

Trivia

  • "Originally every boss/enemy in Isaac was going to resemble Isaac in some way. this is the case for most."[1]
  • Double Trouble boss pools can have bosses from any of the previous chapters' pools, and are the same for both versions of that chapter's floor. This means that, for example, Double Trouble boss fights in the Caves can feature bosses from the Cellar or the Basement, and every Double Trouble fight in the Caves can also be encountered in the Catacombs.
  • Bosses often come in three versions: normal (For example, Monstro), posthumous (Monstro II), and alternate (Gish). Usually, the posthumous boss looks like the original with some horrible mutilation; for example, Monstro and Chub had most of their skin ripped off.
  • Most bosses and their alternate/posthumous forms either share similar death animations or share the fact that they lack death animations.

Bugs

Bug Bug! Defeating a boss quickly enough might cause the boss music to play, even after the boss dies.