1up! / Dead Cat: Familiars are multiplied but do not give Isaac additional lives.
Best Bud: If used before taking damage, the white fly will circle Isaac. However, multiple white flies cannot be spawned, so using Box of Friends after taking damage or using it multiple times in a room creates no effect.
Buddy in a Box: Creates another randomly generated familiar, rather than copying the same one.
Bumbo: Will spawn a level 1 Bumbo regardless of the original Bumbo's current level.
Milk!: The familiar itself doesn't appear, but instead, it decreases tear delay by 2 (effective tears up) when used, without needing to take damage.
Monster Manual: Familiars spawned by Monster Manual are not copied. It will still spawn a Demon Baby if a familiar from Monster Manual is generated and there are no other valid familiars that can be duplicated.
This page was last edited on 4 December 2020, at 03:56.
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