Box of Spiders

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Removed in Afterbirth † Item icon
Added in Afterbirth † Item icon
Item altar
Table dividing line 1.png


Table dividing line 2.png

2 rooms 2 rooms
Table dividing line 3.png

Added in Afterbirth(page 3, column 3, row 3)
Removed in Afterbirth(page 3, column 3, row 9)

Box of Spiders is an activated item.

Effects[edit | edit source]

  • Spawns 1-4 Blue Spiders.
  • Added in Afterbirth † This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.

Notes[edit | edit source]

  • Blue Spiders deal 2.5x the character's damage.
  • Functionally the spider equivalent to Guppy's Head Guppy's Head.

In-game Footage[edit | edit source]

Gallery[edit | edit source]

Seeds[edit | edit source]

 PC  GLVQ 0PMC (Treasure Room adjacent to spawn)

 PC  Added in Afterbirth Normal and hard modes only PHYR RA8L (Treasure Room adjacent to spawn)

 Switch  Greedier mode only 30WN JFEA (First Golden Treasure Room)

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