Brains move around the room slowly, leaving a trail of Red Creep that does half a heart of damage to the player, though they do 1 heart worth of contact damage. They are relatively weak on their own, but can quickly corner Isaac when fought in groups. Two of them are spawned from MemBrains upon death. Brains can also be spawned by Oobs.
Variants[edit | edit source]
Poison Mind[edit | edit source]
Defeat The Lamb
Poison Minds behave like regular Brains, but they crawl diagonally and leave a trail of Green Creep.
Black Globin's Head[edit | edit source]
Black Globin's Heads behave like Brains, but they target Isaac directly, chasing him.
Notes[edit | edit source]
- If Poison Minds aren't unlocked yet, they are replaced by Brains.
- Black Globin's Heads can spawn in Super Secret Rooms.
|The Binding of Isaac: Rebirth|
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