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Removed in Afterbirth † Item icon
Added in Afterbirth † Item icon
Item altar
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Character appearance

Tear appearance
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Added in Afterbirth(page 1, column 15, row 6)
Removed in Afterbirth(page 2, column 5, row 2)

Brimstone is a special passive item.

Effects[edit | edit source]

  • Isaac's tears are replaced with a charged blood laser beam. The beam is piercing and spectral, dealing damage to all enemies and ignoring all obstacles in its path.
    • The laser deals damage equal to Isaac's damage each tick, and ticks a total of 13 times over the course of about 1 second.
    • Tears down: Delay * 3.
  • Added in Afterbirth This item belongs to the Leviathan set. Collecting three items from this set will transform Isaac into Leviathan.

Notes[edit | edit source]

  • Azazel starts the game with a short-ranged, slower charging version of Brimstone. Picking up Brimstone with him will give him the long-ranged version. Without the long-range version, his mini-brimstone won't have enough length to use any homing items.
    • Added in Afterbirth His Brimstone's shorter range can be increased with range up items or pills.
  • If multiple Brimstones are picked up (via Added in AfterbirthDiplopia Diplopia, Added in Afterbirth †Crooked Penny Crooked Penny or on a Victory Lap), then another beam is added, with no increase in charge time.
    • Although extremely unlikely, a total of 16 blood beams can be on screen at a time (including beams shot with tear-increasing items, such as 20/20 20/20). If another Brimstone is picked up, the beams' span will widen.
  • The beam will apply status effects and does so frequently thanks to its high tick rate.
  • Multi-shot effects will increase the number of beams accordingly, with exceptions listed below.

Synergies[edit | edit source]

  • Added in Afterbirth8 Inch Nails 8 Inch Nails: Beams gain knockback, pushing enemies away in the direction they travel but not out of their path. This increases its consistency.
  • Added in Afterbirth †Apple! Apple! / Added in Afterbirth †Euthanasia Euthanasia / Tough Love Tough Love: The beam can gain the damage multiplier from each of the items, although there is no visual difference. The bonus applies for the whole beam and not on a per-tick basis. Euthanasia loses its instant kill ability, however.
  • Anti-Gravity Anti-Gravity: An orb of energy expands, then shrinks while firing the beam after a delay. The orb still hurts enemies if they touch it. Isaac can start charging a new shot immediately after releasing the fire key without canceling the first shot, effectively allowing for a faster firing rate. It makes it harder to hit enemies with Azazel as the beam does not increase in range.
    • Anti-Gravity + Added in AfterbirthIncubus Incubus: Isaac will fire Brimstone orbs, while Incubus will fire regular Brimstone beams.
  • Fire Mind Fire Mind: The beam will not cause explosions, but will still set enemies on fire.
  • Guppy: Blue flies are spawned at a rate of approximately one blue fly per tick of damage for each enemy it hits. This causes a lot of blue flies to spawn very quickly. The spawned blue flies will also move to attack the targeted enemy immediately.
  • Added in Afterbirth †Haemolacria Haemolacria: Increased charge time. Tears will burst into several beams that are fired in random directions.
  • Homing tears: The beam will make sharp turns and even loops to hit enemies. Azazel's mini-brimstone does not home unless he has a high range stat.
  • Hook Worm Hook Worm: Beam shifts left to right while firing straight and forms angles that constantly flatten and expand, effectively increasing its width.
  • Loki's Horns Loki's Horns: Occasionally causes Isaac to fire the beam in all four cardinal directions, similarly to Head of Krampus Head of Krampus's effect.
  • The Ludovico Technique The Ludovico Technique: The beam forms a large ring that is controllable and does not need to be charged. Enemies inside the ring without touching it are not hurt. The shot speed is ignored. The tears stat is ignored and the damage is dealt very rapidly at a rate equivalent to a 2 tear delay.
  • Added in AfterbirthA Lump of Coal A Lump of Coal: The beam gradually increases in size and damage the farther it travels, with the damage increasing on a multiplier that is roughly +20% per tile of distance. This allows for a huge damage increase from longer distances. Beam is colored black.
  • Mom's Eye Mom's Eye: Adds a chance to shoot a beam from the back of Isaac's head.
  • Mom's Knife Mom's Knife: Adds a small barrage of knives after the main knife is fired, with each knife doing 80% of Isaac's tear damage. The barrage of knives goes all the way across the screen and increases in quantity the longer the charge.
  • Mom's Wig Mom's Wig: Holding down a fire button to charge the attack very rapidly rolls the probability to spawn blue spiders; releasing to fire the beam, however, does not.
  • Added in AfterbirthMonstro's Lung Monstro's Lung: Fires 3-5 additional Brimstone beams in random directions around Isaac with no increase in charge time. Charging a new Brimstone beam removes the original from in front of Isaac, but not the additional ones added by Monstro's Lung. This effectively increases the fire rate.
  • Added in AfterbirthRubber Cement Rubber Cement: Beams bounce off of walls, creating a second beam that deals half damage.
    • Added in Afterbirth If Azazel's mini Brimstone beam bounces off a wall, it effectively becomes a full-length Brimstone beam, but it will still only deal half damage.
      • Added in Afterbirth † Azazel's Brimstone no longer becomes a full length beam after bouncing, and instead bounces as a regular mini-Brimstone.
  • Sad Bombs Sad Bombs: Upon exploding, bombs release ten beams in all directions that benefit from the item's flat damage bonus.
  • Strange Attractor Strange Attractor: Enemies are attracted towards the beam, improving its consistency. Consumables will also be moved by the beam.
  • Tammy's Head Tammy's Head: Shoots ten beams in all directions that benefit from the item's flat damage bonus. Given the item's single room charge, this makes for an extremely powerful synergy.
  • Added in AfterbirthTechnology Technology: The Technology laser coils around the Brimstone beam, granting a 1.5x damage multiplier (it stacks with other similar multipliers like Cricket's Head Cricket's Head or Magic Mushroom Magic Mushroom).
  • Added in AfterbirthTech X Tech X: Brimstone becomes a large laser ring that varies in size depending on how long it is charged before firing. The tear delay is that of Tech X.
    • Tech X + A Lump of Coal A Lump of Coal: The Brimstone ring increases in size and damage the further it travels.
    • Tech X + Mom's Knife Mom's Knife: Mom's Knife and a Mom's Knife+Brimstone barrage are shot alongside the rings.
  • Tiny Planet Tiny Planet: The beam will wrap around Isaac once and then shoot straight forward.
  • Wiggle Worm Wiggle Worm: Beam becomes wavy while firing straight, effectively increasing its width.

Interactions[edit | edit source]

  • Removed in Afterbirth20/20 20/20: Overridden by Brimstone.
  • Chocolate Milk Chocolate Milk: Reduces Isaac's tear delay by 20%. Doesn't increase damage.
  • Added in Afterbirth †Compound Fracture Compound Fracture/Cricket's Body Cricket's Body/The Parasite The Parasite: Splitting is overridden by Brimstone, but stat effects are still applied.
  • Added in AfterbirthContinuum Continuum: Overridden by Brimstone.
  • Cursed Eye Cursed Eye: Overridden by Brimstone.
  • Removed in AfterbirthDr. Fetus Dr. Fetus: Overrides Brimstone.
    • Added in Afterbirth Both fire normally; Isaac shoots bombs while charging Brimstone.
  • Removed in AfterbirthEpic Fetus Epic Fetus: Overrides Brimstone.
    • Added in Afterbirth After the missile hits the ground, it spawns 10 Brimstone beams similar to the effect given by Sad Bombs. Azazel's mini-brimstone does not give the Sad Bombs effect.
  • Added in AfterbirthEvil Eye Evil Eye: Overridden by Brimstone.
  • Added in Afterbirth †Flat Stone Flat Stone: Overridden by Brimstone.
  • Added in Afterbirth † The Forgotten: The charged attack will spawn a Brimstone ball that will float in front of The Forgotten for a few seconds before disappearing. The Forgotten will still melee attack while performing this action.
  • Added in AfterbirthHoly Light Holy Light: Overridden by Brimstone.
  • Ipecac Ipecac: Isaac gains only the poison effect without either the increased damage nor the decreased fire rate.
    • Added in Afterbirth † Isaac shoots Ipecac tears while charging Brimstone. Both Brimstone and Ipecac shots modify Isaac's damage and tear delay stat, meaning that Ipecac fires slower and Brimstone charges slower, but Brimstone deals drastically increased damage. The beam is colored yellowish-green. Take care to pre-charge Brimstone so that the Ipecac shot is on cooldown as Isaac enters a room.
  • Isaac's Tears Isaac's Tears: Fires normal tears, but nearly instantly charges when charging Brimstone.
  • Added in Afterbirth †Jacob's Ladder Jacob's Ladder: Overridden by Brimstone.
  • Added in AfterbirthKidney Stone Kidney Stone: Overridden by Brimstone.
  • Added in Afterbirth †Lachryphagy Lachryphagy: Overridden by Brimstone.
  • Added in Afterbirth †Lead Pencil Lead Pencil: Overridden by Brimstone.
  • Removed in AfterbirthA Lump of Coal A Lump of Coal: No effect.
  • Added in AfterbirthMarked Marked: Overridden by Brimstone.
  • Removed in AfterbirthMonstro's Lung Monstro's Lung: Overridden by Brimstone.
  • Removed in AfterbirthMy Reflection My Reflection: Overridden by Brimstone.
    • Added in Afterbirth Makes the beam curve when moving. It has the same effect on Azazel's mini-brimstone but doubles the range.
  • Mysterious Liquid Mysterious Liquid: Overridden by Brimstone.
    • Added in Afterbirth When Brimstone hits enemies or walls, it leaves creep based on how long it hits.
  • Number One Number One + Azazel: Although Number One is otherwise purely beneficial with standard Brimstone, Azazel's range is severely affected.
  • Added in Afterbirth †Pop! Pop!: Overridden by Brimstone.
  • Proptosis Proptosis: Damage is doubled with no drop-off at the range.
    • Added in Afterbirth Damage is doubled twice, for a total of 4x next to Isaac, but quickly drops further along the beam, at about 0.8x per tile of distance.
  • Added in AfterbirthPupula Duplex Pupula Duplex: Overridden by Brimstone.
  • Removed in AfterbirthRubber Cement Rubber Cement: Overridden by Brimstone.
  • Removed in AfterbirthTechnology Technology: Overridden by Brimstone.
  • Added in Afterbirth †Technology Zero Technology Zero: Overridden by Brimstone.
  • Technology 2 Technology 2: Overridden by Brimstone, but retains the reduced damage.
    • Added in Afterbirth Both fire normally; the Technology laser fires while charging Brimstone.
  • Tech.5 Tech.5: Overridden by Brimstone unless using Azazel, in which case it will fire normally while charging Brimstone.
    • Added in Afterbirth Tech.5 fires normally while charging Brimstone.
  • Added in Afterbirth †Trisagion Trisagion: Overridden by Brimstone.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • The term brimstone (burn stone) comes from the King James Bible's mention of burning sulfur. It is used in the phrase "fire and brimstone" to describe the torments of hell. While solid sulfur is yellow, molten sulfur is blood red.
  • Brimstone's item icon originally comes from the alchemical symbol for sulfur, referred to as the Leviathan Cross. It was later adopted by Anton LaVey in The Satanic Bible to represent hell and is now often associated with Satanism.
  • The ram horns gained from picking up Brimstone were added as a cosmetic item to Team Fortress 2 to promote The Binding of Isaac: Rebirth. If the game was purchased before the 10th of December, players were awarded the item in genuine quality.
  • Most items that change tear color will also give Brimstone an exotic appearance, but they do not combine and only one color effect is shown.

Gallery[edit | edit source]

Seeds[edit | edit source]

 PC  Hard mode only DQY7 QK7M (The Basement XL: Second boss's Devil Room)

 PC  Added in Afterbirth Normal and hard modes only QW44 N10D (Second floor Devil Room; Isaac may proceed normally, but all other characters must not enter the first floor Treasure Room)

 PC  Added in Afterbirth Normal and hard modes only B8TK KNEP (Second floor Devil Room)

 Vita  LHVK 9NTS (Second floor Devil Room)

 PS4  SSH7 STDS (Second Floor Devil Room)

 Switch  Added in Afterbirth † Hard mode only DBDR SJGV (First floor Devil Room)

 3DS  Hard mode only EXDL 3P62 (First floor Devil Room)

Bugs[edit | edit source]

Bug Bug! Picking up Brimstone before picking up Scorpio will not change the beam's color. Picking up Scorpio before Brimstone, however, will change it to green.

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