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| Pick up 5 familiars in a single runBuddy in a Box|
Buddy in a Box is an unlockable passive item added in Booster Pack #1.
- Grants a familiar with random tear effects, fire rate and damage.
- The familiar takes the appearance of a random co-op baby.
- The familiar is randomized upon entering a new floor.
- The familiar's tear appearance isn't linked to the normal effect such tears would have.
- For instance, piercing-looking tears might not go through enemies and Sinus InfectionAdds a chance to fire a booger which sticks to enemies and poisons them. tears might not stick, while tears that do not look like Compound FractureIncreases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle. tears can still split on hit.
- Some tear effects like ProptosisTears start out massive with high damage, and then shrink down and become weaker over a short range. and Tiny PlanetRange up and makes shot tears revolve around Isaac until they drop. do not have their associated stat boosts and thus are very ineffective.
- Familiars with the Serpent's KissTears now have a random chance to apply a poison effect, causing 4 or 6 damage per tick to enemies (Similar to The Common Cold item). Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick). Enemies that were poisoned have a chance to drop a black heart when killed. effect can drop black hearts when an enemy is killed.
- Familiars will not deal contact damage.
- Box of FriendsUpon use, duplicates all of Isaac's familiars for the current room.: Spawns a new randomly generated familiar.
Switch GQHY GCE6 (First Golden Treasure Room)