Bursting Sack is a passive item added in The Binding of Isaac: Afterbirth.
Effect
- Certain spider enemies no longer target or deal contact damage to Isaac, nor actively spawn other enemies. Spiders that are spawned from enemies that are not affected by Bursting Sack will also remain neutral.
- Affected spider enemies include: Spider, Big Spider, Level 2 Spider, Ticking Spider, Baby Long Legs, Small Baby Long Legs, Crazy Long Legs and Small Crazy Long Legs.
Spiders and Big Spiders don't blink red when Isaac has the item.
- Unaffected spider enemies include: Trite, Ragling, Rag man's Rag Ling, Blister, Wall Creep, Blind Creep, Rage Creep and The Thing.
- Affected spider enemies include: Spider, Big Spider, Level 2 Spider, Ticking Spider, Baby Long Legs, Small Baby Long Legs, Crazy Long Legs and Small Crazy Long Legs.
In-game Footage
Trivia
- This item is similar to Skatole, only affecting spiders instead of flies.
- Hence the name, this item's appearance is similar to a bursting Sack.
Seeds
PC 
Z0MB 7AMP (First floor Treasure Room)
Switch 2MFE VQC9 (Treasure Room next to spawn)
Bugs
 Bug!
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Spider enemies that are neutralized by Bursting Sack cannot be poisoned by contact via  The Virus,  Serpent's Kiss or turned into gold via  Midas' Touch. They also become immune to contact damage from  My Little Unicorn,  The Gamekid and  The Nail, but not the damage from Midas' Touch or  Little Horn.
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 Spider Items
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| Items |
 The Binding of Isaac: Rebirth
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