Butter! is an unlockable trinket added in Booster Pack #1.
- Using an active item will drop it onto a pedestal on the ground.
- When Isaac takes damage, there is a 2% chance one of Isaac's passive items will drop on the ground.
- VoidConsumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades.: Items that are normally unusable when holding Butter! can still activate their effects if absorbed by Void.
- Consumable actives: Active items that remove themselves upon use do not drop and are consumed as normal.
- Controllable actives: Active items that require additional input to control after being used (like The CandleThrows out a blue flame that can pass over gaps (but not through rocks). The flame damages anything in its path. or Breath of LifeGrants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage.) create no effect and are dropped on the ground. They retain charge when picked up.
- Familiar spawning actives: Active items that spawn blue flies, blue spiders, or items like Monster ManualSummons a random familiar for the current room. Can summon familiars not yet unlocked. will spawn those familiars before dropping.
- This applies to active items that spawn pickups.
- Glowing Hour GlassWhen used, this item will rewind time, put Isaac back in the previous room, and undo anything that happened in the current room. Any health, pickups, or items gained or lost will be reset back to the previous state.: Is removed from Isaac and dropped, but is given back to Isaac discharged upon going back in time into the previous room. The room in which Glowing Hour Glass was used will not contain another Glowing Hour Glass.
- How to JumpGives Isaac the ability to jump (over gaps, spikes, etc.).: Isaac animates a jump but his movement remains normal and he cannot go over any obstacles.
- MetronomeGrants a random item effect for the current room.: Effect from the Metronome is immediately canceled beyond the gain of hearts, coins, bombs, or keys. Visual effects may persist until leaving the room.
- Razor BladeUpon use, deals one heart of damage to Isaac and grants +1.2 damage for the current room.: Deals damage to Isaac as normal but does not increase damage for the current room.
Butter! will immediately cancel the effects of and discharge these active items when dropped, unless they are consumed with VoidConsumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades..
- Anarchist CookbookSpawns six troll bombs around the room.
- Black HoleThrows a black hole on the ground which sucks in and damages enemies.
- The Book of BelialUpon use increases damage by 2 for the current room and by a further +50% if the character also has the Blood of the Martyr.
Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it, or increases the chance by 12.5%.
- The BoomerangThrows a short-range boomerang which does a bit of damage and has a high chance to stun the enemy for 2 seconds. Can also be used to grab pickups.
- Breath of LifeGrants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage.
- Brown NuggetSpawns a stationary fly familiar that fires tears at nearby enemies.
- Crack the SkySummons multiple beams of light in random locations around the room, dealing a large amount of damage to any enemy that touches them.
- D InfinityGrants a random dice item that changes each use.
- Doctor's RemoteSets a big red target on the ground (similar to the Epic Fetus item) which can be controlled with tear controls. After 6 seconds or by pressing space again, a huge explosive missile hits it, which damages all enemies caught in its blast radius.
- Friendly BallThrowing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be friendly, fighting for Isaac and persisting between rooms.
- The GamekidUpon use, turns the character into a into a Pac-Man-like creature for 5 seconds, granting invulnerability, inflicting fear on all enemies, and replenishing half a red heart container for every two enemies killed.
- Glass CannonWhen used, reduces Isaac's health to half a heart (including soul and black hearts) and fires one large piercing spectral tear that does a lot of damage. The damage done by Glass Cannon scales with Isaac's damage (at base damage it does 45 damage).
- The HourglassUpon activation, enemies and their projectiles are slowed down for a short duration.
- My Little UnicornUpon use, grants invulnerability and increased speed for five seconds, removing the ability to shoot tears and replacing it with the ability to deal contact damage to enemies.
- The NailAdds one soul heart and allows the breaking of rocks and damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.
- Notched AxeIsaac holds the axe above his head for as long as the spacebar button is held (or until he leaves the room). While holding the axe, Isaac can break any rock he touches, but cannot attack or pick up other items.
- PauseFreezes all enemies until a fire button is pressed.
- A PonyPassively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies.
- ScissorsUpon use, turns Isaac's head into a stationary familiar for the current room which fires normal tears that deal 3.5 damage.
- Shoop Da Whoop!Fires a laser from Isaac's mouth.
- SprinklerUpon use, spawns a sprinkler that rotates and fires tears.
- Telepathy for DummiesUpon activation, grants homing tears for the current room.
- Unicorn StumpUpon use, grants invulnerability and increased speed for five seconds, but removes the ability to shoot tears.
- White PonyPassively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack the Sky.
- Wooden NickelWhen used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).
- Butter! was made by Florian Himsl (developer and programmer of the original The Binding of Isaac game).
| Booster Packs
- Angry Fly
Spawns a fly familiar that orbits around a random enemy and deals 5 damage per tick to enemies it comes in contact with.
- Black Hole
Throws a black hole on the ground which sucks in and damages enemies.
Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
- Broken Modem
Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
- Mystery Gift
Upon use, spawns a random item from the current room's item pool, with a chance to spawn A Lump of Coal or The Poop instead.
Upon use, spawns a sprinkler that rotates and fires tears.
- Fast Bombs
Grants 7 bombs and allows bombs to be placed rapidly.
- Buddy in a Box
Grants a familiar with a random tear effect. The familiar is randomized at the start of each floor.
- Lil Delirium
Grants a familiar that transforms into another random familiar every 10 seconds.
- HairpinFully recharges Isaac's active item upon entering a boss fight.
- Wooden CrossGrants a Holy Mantle shield upon entering a new floor, which protects against one hit of damage.
- Butter!Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping a passive item.
- Huge GrowthMakes Isaac large for the current room, increasing his range and damage.
- Ancient RecallSpawns 3 random cards.
- Era WalkFor the current room, enemies are slowed, Isaac's speed is increased, and his shot speed is decreased.
- Jumper Cables
Grants an active item charge every 15 enemies killed.
Upon use, makes a random item from a shop, devil deal, or black market free.
Upon use, for the next two seconds, any enemy shots that come near Isaac are held in place. After the charge is depleted, they are fired back as tears.
- Moving Box
If the box is empty, picks up all items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room.
- Technology Zero
Connects Isaac's tears with electricity that can damage enemies.
Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots.
- Filigree FeatherAngels drop items instead of key pieces when defeated.
- 7 Seals
Grants a random Harbinger familiar that changes every 10 seconds.
- Mr. ME!
Summons a controllable ghost that can perform various tasks depending on what it targets.
- Angelic Prism
Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle.
- Door StopThe last door Isaac went through stays open, allowing him to leave the room even if enemies are in it.
- Death's List
Grants a reward if all enemies in a room are killed in the order they are marked.
Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
Tears are replaced with piercing white blasts of light.
Allows Isaac to hold two active items.
- Extension CordBeams of yellow electricity flow between Isaac and his familiars, damaging any enemies between them.
Grants one soul heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears.
- Sacrificial Altar
Upon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.
- Lil Spewer
Spawns a random pill, and grants a small Spewer familiar that charges up and fires different types of creep.
Spawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.
- Mystery Egg
Spawns an egg familiar, which cracks and turns into a random friendly enemy when Isaac is hurt. The egg regenerates upon entering a different room.
- Flat Stone
Tears bounce off the floor. Tears that hit an enemy after bouncing deal splash damage to all nearby enemies for 25% of Isaac's tear damage.
Grants one bone heart and spawns three red heart pickups.
- Slipped Rib
Spawns a bone familiar that circles around Isaac and reflects enemy shots.
- Hallowed Ground
Spawns a white poop familiar, which turns into a white poop when Isaac is hurt.
- Pointy Rib
Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
- Book of the Dead
Upon use, spawns a friendly Bony or an orbital bone for each enemy killed in the current room.
- Dad's Ring
Creates a ring of light around Isaac that petrifies enemies in contact.
- Divorce Papers
Spawns a Mysterious Paper, increases tears, and grants a bone heart.
- Jaw Bone
Spawns a familiar that flies the room while firing, dealing a flat 7 damage to enemies that come in contact and retrieving pickups.
- Brittle Bones
Replaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up.
- Broken Shovel
While held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel.
- Broken Shovel
One of two parts necessary to create Mom's Shovel.
- Mom's Shovel
Spawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in Dark Room.
- Rotten PennySpawns a blue fly every time a coin is picked up.
- Baby-BenderGrants Isaac's familiars homing shots.
- Finger BoneGrants a chance to gain a bone heart upon taking damage.