Cain

3.5(*1.20) 1   1 17.75 1.3 0   1 Key Paper Clip Golden Chests can be opened without using a key. Lucky Foot +1 Luck. Increases chance of winning Shell Game Beggar. (Independent of luck stat)   Hold 55 coins at one time Cain

Cain is unlocked when the player is in possession of 55 or more coins at once in a run. Cain appeared in the original Binding of Isaac. He starts with two red heart containers, the Lucky Foot

+1 Luck. Increases chance of winning Shell Game Beggar. (Independent of luck stat)

, and one key. Cain will also start with the Paper Clip

Golden Chests can be opened without using a key.

trinket if 68 coins have been donated to the Greed Machine.

Notes

• Cain can only shoot tears from his right eye. This affects certain items: Blood Clot

  Increases damage by 1 and range by 5 for tears fired from the left eye.

  and Chemical Peel

  Tears fired from left eye do increased damage.

  have a 50% chance to do increased damage and Technology 2

  Decreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously.

  will prevent him from firing normal tears, even tear-changing effects like Brimstone

  Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.

  . Also, the R U A Wizard? pill will cause Cain to fire tears to his right exclusively.

Unlockable items

• Cain's Other Eye - Complete the Boss Rush as Cain.

• Glass Baby - Defeat Mom's Heart on hard mode as Cain.

• A Bag of Bombs - Defeat Satan as Cain.

• A Bag of Pennies - Defeat Isaac as Cain.

• Abel - Defeat The Lamb as Cain.

• Cain's Eye - Defeat ??? as Cain.

• Evil Eye - Defeat Ultra Greed as Cain.

• Sack of Sacks - Defeat Ultra Greedier as Cain.

• D12 - Defeat Hush as Cain.

• Green Baby - Defeat Mega Satan as Cain.

• Silver Dollar - Defeat Delirium as Cain.

• Picky Baby - Earn all hard mode completion marks as Cain.

Trivia

• Cain is a reference to the Biblical story of Cain and Abel, in which Cain commits the first murder by killing Abel.
  • Abel

    A familiar that mirrors the player's movements and shoots in the opposite direction.

    also appears as an item in Rebirth.
• Glass Baby could be a reference to Cain having a glass eye.

Characters
Rebirth	Afterbirth	Afterbirth †