Cambion Conception

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Font TeamMeat C.pngFont TeamMeat a.pngFont TeamMeat m.pngFont TeamMeat b.pngFont TeamMeat i.pngFont TeamMeat o.pngFont TeamMeat n.png   Font TeamMeat C.pngFont TeamMeat o.pngFont TeamMeat n.pngFont TeamMeat c.pngFont TeamMeat e.pngFont TeamMeat p.pngFont TeamMeat t.pngFont TeamMeat i.pngFont TeamMeat o.pngFont TeamMeat n.png
Removed in Afterbirth †Item icon
Added in Afterbirth †Item icon
Item altar
 
 
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5.100.412
 
Character appearance
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Devil Room Devil Room
Greed mode only Devil Room Devil Room
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Added in Afterbirth †(page 4, column 7, row 3)
Removed in Afterbirth †(page 4, column 7, row 3)
 
Cambion Conception Defeat ??? as LilithCambion ConceptionCambion Conception
Added in Afterbirth

Cambion Conception is an unlockable passive item added in The Binding of Isaac: Afterbirth.

Effects[edit | edit source]

  • Upon taking damage a certain number of times, Isaac gains a permanent demonic familiar. Possible familiars include:
  • The first and second familiars will each spawn after taking damage 15 times. The third and fourth familiars will each spawn after taking damage 30 more times. No further familiars will spawn. As a result, after taking damage 90 times, four out of six possible familiars will have spawned.
  • Isaac will look progressively more pregnant as he takes damage.

Notes[edit | edit source]

  • Lilith starts with this item by default, even if it hasn't been unlocked.
  • Only one of each type of familiar can be spawned.
  • Only actually getting damage counts towards the payout. For example, disrupting the Holy Mantle Holy Mantle shield while keeping your heart containers full will not spawn any familiars.
  • Familiars spawned this way do not count towards transformations nor the Collection Page.
  • Familiars spawned by the item do not affect item pools, so multiple copies of one familiar can be obtained. For example, a second Incubus can be purchased after Cambion Conception spawns one.
  • If a familiar obtained is a copy of another one you've already obtained, using Box of Friends Box of Friends will only clone one of that familiar, similarly to the Box of Friends's effects on cloned familiars that it spawns.
  • This item is the demonic counterpart to Immaculate Conception Immaculate Conception.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • In mythology, a cambion is the offspring of a human and an incubus or succubus.
  • During the development of Afterbirth, Edmund McMillen asked on Twitter what the opposite of Immaculate Conception Immaculate Conception would be called. 27 people replied with suggestions, but none of them were used.


Lilith Unlocks Lilith Unlocks Lilith Unlocks
IncubusIncubusDefeat Hush as LilithBox of FriendsBox of FriendsDefeat Ultra Greed as LilithBig BabyBig BabyDefeat Mega Satan as LilithRune BagRune BagDefeat Isaac as LilithCambion ConceptionCambion ConceptionDefeat ??? as LilithSerpent's KissSerpent's KissDefeat Satan as LilithSuccubusSuccubusDefeat The Lamb as LilithImmaculate ConceptionImmaculate ConceptionComplete the Boss Rush as LilithGoat Head BabyGoat Head BabyDefeat Mom's Heart on hard mode as LilithDark BabyDark BabyEarn all hard mode completion marks as Lilith EuthanasiaEuthanasiaDefeat Delirium as LilithDualityDualityDefeat Ultra Greedier as Lilith
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