Chapters

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Chapters are sets of floors which contain similar enemies, themes, bosses, and difficulties. Earlier chapters are divided into two floors, while later chapters contain one floor. Each chapter has different environments which, while retaining the same feel, have slightly different themes, enemies, bosses, and difficulties. Each environment also has its own music.

Chapter 1

The Basement The Cellar Burning Basement
The Basement The Basement The Cellar The Cellar Added in Afterbirth Burning Basement Burning Basement

Chapter 2

The Caves The Catacombs Flooded Caves
The Caves The Caves The Catacombs The Catacombs Added in Afterbirth Flooded Caves Flooded Caves

Chapter 3

The Depths Necropolis Dank Depths
The Depths The Depths Necropolis Necropolis Added in Afterbirth Dank Depths Dank Depths

Chapter 4

The Womb Utero Scarred Womb
The Womb The Womb Utero Utero Added in Afterbirth Scarred Womb Scarred Womb

Chapter 4.5 (Optional)

???
Added in Afterbirth ??? ???

Chapter 5

Cathedral Sheol
Cathedral Cathedral Sheol Sheol

Chapter 6

The Chest Dark Room
The Chest The Chest Dark Room Dark Room

Endgame (optional)

The Void
Added in Afterbirth † The Void The Void

Level Generation

For the technical details of how each level / floor is generated, see Level Generation.


SmallIsaac.pngChaptersSmallIsaac.png
Chapter 1 Chapter 2 Chapter 3 Chapter 4 Optional Chapter 5 Chapter 6 Endgame
Normal mode only
Hard mode only
Stage The Basement icon.png Stage The Caves icon.png Stage The Depths icon.png Stage The Womb icon.png Stage Sheol icon.png
Sheol


Stage Cathedral icon.png
Cathedral
Stage Dark Room icon.png
Dark Room


Stage The Chest icon.png
The Chest
The Basement The Caves The Depths The Womb
Stage The Cellar icon.png Stage The Catacombs icon.png Stage Necropolis icon.png Stage Utero icon.png ??? Stage The Void icon.png
The Cellar The Catacombs Necropolis Utero ??? The Void
Stage Burning Basement icon.png Stage Flooded Caves icon.png Stage Dank Depths icon.png Stage Scarred Womb icon.png
Burning Basement Flooded Caves Dank Depths Scarred Womb
Greed mode only
Greedier mode only
Stage The Basement icon.png Stage The Caves icon.png Stage The Depths icon.png Stage The Womb icon.png Stage Sheol icon.png The Shop Ultra Greed
The Basement The Caves The Depths The Womb Sheol The Shop Ultra Greed
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets