Chapter 1 (Bosses)

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Bosses
Chapter 1 Chapter 2 Chapter 3 Chapter 4 Added in Afterbirth ??? Chapter 5 Chapter 6 Added in Afterbirth † The Void
Universal Devil and Angel Room Seven Deadly Sins Added in Afterbirth Greed Mode All Mini-Bosses All Bosses

The Basement[edit | edit source]

Boss Dingle.png
Boss The Duke of Flies.png
 Boss Gemini.png
Boss Gurglings.png
Dingle The Duke of Flies Gemini Gurglings
Boss Larry Jr..png
 Boss Monstro.png
Boss The Fallen.png
Boss Famine.png
Larry Jr. Monstro The Fallen Requires previous entry into a devil room Famine Needs to be unlocked
Boss The Headless Horseman.png
 Boss Steven.png
Boss Dangle.png
The Headless Horseman Needs to be unlocked Steven Needs to be unlocked Dangle Added in Afterbirth Needs to be unlocked
Boss Little Horn.png
Boss Rag Man.png
Boss Turdlings.png
Little Horn Added in Afterbirth Needs to be unlocked Rag Man Added in Afterbirth Needs to be unlocked Turdlings Added in Afterbirth Needs to be unlocked

The Cellar[edit | edit source]

Boss Blighted Ovum.png
Boss The Duke of Flies.png
Boss Fistula.png
Boss The Haunt.png
Blighted Ovum The Duke of Flies Fistula The Haunt
Boss Pin.png
Boss Widow.png
Boss The Fallen.png
Boss Famine.png
Pin Widow The Fallen Requires previous entry into a devil room Famine Needs to be unlocked
Boss The Headless Horseman.png
Boss Little Horn.png
Boss Rag Man.png
The Headless Horseman Needs to be unlocked Little Horn Added in Afterbirth Needs to be unlocked Rag Man Added in Afterbirth Needs to be unlocked

Burning Basement Added in Afterbirth[edit | edit source]

Boss The Duke of Flies.png
Boss Larry Jr..png
Boss The Haunt.png
The Duke of Flies Larry Jr. The Haunt
Boss Monstro.png
Boss The Fallen.png
Boss Famine.png
Monstro The Fallen Requires previous entry into a devil room Famine Needs to be unlocked
Boss The Headless Horseman.png
Boss Little Horn.png
Boss Rag Man.png
The Headless Horseman Needs to be unlocked Little Horn Added in Afterbirth Needs to be unlocked Rag Man Added in Afterbirth Needs to be unlocked

Greed mode only The Basement Added in Afterbirth[edit | edit source]

Boss Dingle.png
Boss The Duke of Flies.png
 Boss Gemini.png
Dingle The Duke of Flies Gemini
Boss Larry Jr..png
 Boss Monstro.png
Boss Famine.png
Larry Jr. Monstro Famine
Boss The Headless Horseman.png
 Boss Steven.png
Boss Gurglings.png
The Headless Horseman Steven Gurglings
Boss The Haunt.png
 Boss Pin.png
Boss Widow.png
The Haunt Pin Widow
Boss Mega Fatty.png
Boss Polycephalus.png
Lust.png
Mega Fatty Polycephalus Lust
Boss Envy.png
Gluttony.png
Wrath.png
Boss Rag Man.png
Envy Gluttony Wrath Rag Man

Notes[edit | edit source]


Bosses Boss Monstro.png
Chapter 1
Stage The Basement icon.pngStage The Cellar icon.pngStage Burning Basement icon.png 		Blighted Ovum • Dingle • The Duke of Flies • Famine • Fistula • Gemini • Gurglings • The Haunt • Larry Jr. • Monstro • Pin • Steven • Widow • The Fallen • The Headless Horseman
Dangle • Little Horn • Rag Man • Turdlings
Chapter 2
Stage The Caves icon.pngStage The Catacombs icon.pngStage Flooded Caves icon.png 		Carrion Queen • C.H.A.D. • Chub • Dark One • Gurdy • Gurdy Jr. • The Hollow • The Husk • Mega Fatty • Mega Maw • Peep • Pestilence • Polycephalus • The Wretched • The Fallen • The Headless Horseman
The Forsaken • The Frail • The Stain
Big Horn • Rag Mega
Chapter 3
Stage The Depths icon.pngStage Necropolis icon.pngStage Dank Depths icon.png 		The Adversary • The Bloat • The Cage • The Gate • Gish • Loki • Mask Of Infamy • Monstro II • War • The Fallen • The Headless Horseman • Mom
Brownie
Sisters Vis
Chapter 4
Stage The Womb icon.pngStage Utero icon.pngStage Scarred Womb icon.png 		Blastocyst • The Bloat • Conquest • Daddy Long Legs • Death • Lokii • Mama Gurdy • Mr. Fred • Scolex • Teratoma • Triachnid • The Fallen • The Headless Horseman • Mom's Heart • It Lives
Sisters Vis • The Matriarch
Blue Womb
??? 		Hush
Chapter 5
Stage Sheol icon.pngStage Cathedral icon.png 		Satan • Isaac
Chapter 6
Stage Dark Room icon.pngStage The Chest icon.png 		??? • The Lamb • Mega Satan
The Void
Stage The Void icon.png 		Delirium
Greed Mode
Ultra Greed 		Ultra Greed
Ultra Greedier
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
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Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets
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