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Disambig.png This article is about the main player character. For the additional multiplayer characters, see Babies. For non-player characters, see NPCs.

There are eleven playable characters in The Binding of Isaac: Rebirth with three extra characters in the DLCs. Five of these characters (Isaac, Magdalene, Cain, Judas, and ???/Blue Baby) came with the original Binding of Isaac, while two additional characters (Eve and Samson) were added later. Eve was added in the Binding of Isaac's Halloween Update, while Samson was added in The Wrath of the Lamb expansion. Rebirth contains four new characters (Azazel, Lazarus, Eden, and The Lost). In the Afterbirth expansion for Rebirth, one new character (Lilith) was added, plus one more character via an update (Keeper). In the Afterbirth † expansion for Rebirth one character (Apollyon) was added. Each character starts with different stats and abilities that give them their own unique play style.

Each character's progress can be gauged by checking their completion marks.

Rebirth Afterbirth Afterbirth †
Character Isaac App.png
Magdalene App.png
Cain App.png
Judas App.png
Blue Baby App.png
Eve App.png
Samson App.png
Azazel App.png
Lazarus App.png
Eden App.png
The Lost App.png
The Lost
Lilith App.png
Keeper App.png
Apollyon App.png
Health Stat Icon.png Health HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Red Heart.png HUD Red Heart.png HUD Soul Heart.pngHUD Soul Heart.pngHUD Soul Heart.png (no heart containers) HUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Black Heart.pngHUD Black Heart.pngHUD Black Heart.png HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Soul Heart.pngHUD Red Heart.png
(Random, up to 3 total)
No health HUD Red Heart.pngHUD Black Heart.pngHUD Black Heart.png HUD Coin Heart.pngHUD Coin Heart.png HUD Red Heart.pngHUD Red Heart.png
Damage Stat Icon.png Damage 3.5 (*1.00) 3.5 (*1.00) 3.5 (*1.20) 3.5 (*1.35) 3.5 (*1.05) 3.5 (*0.75)
(*1.00 at HUD Red Heart.png)
3.5 (*1.00) 3.5 (*1.50) 3.5 (*1.00) 3.5
3.5 (*1.00) 3.5 (*1.00) 3.5 (*1.20) 3.5 (*1.00)
Tears Stat Icon.png Tears +0 +0 +0 +0 +0 +0 -0.05 +0.5, *1/3 +0 ±0.75 +0 +0 +18 +0
Shot Speed Stat Icon.png Shot Speed 1 1 1 1 1 1 1.31 1 1 1 ± 0.25 1 1 1 1
Range Stat Icon.png Range 23.75 23.75 17.75 23.75 23.75 23.75 18.75 17.75 17.75 23.75 ± 5.00 23.75 23.75 23.75 23.75
Speed Stat Icon.png Speed 1.0 0.85 1.3 1.0 1.1 1.23 1.1 1.25 1.0 1.0 ± 0.15 1.0 1.0 0.85 1.0
Luck Stat Icon.png Luck 0 0 0 0 0 0 0 0 -1 0 ± 1 0 0 -2 0
Starting Item Icon.png Starting Pickup(s) x1 bombs Added in Afterbirth † Needs to be unlocked x1 Speed Up pill x1 keys,
Added in Afterbirth Needs to be unlocked Paper Clip Paper Clip
x3 coins None None Added in Afterbirth † Needs to be unlocked Child's Heart Child's Heart 0 - The Fool 0 - The Fool x1 pills x0-2 bombs
x0-1 keys
x0-5 coins
x0-1 trinket, pill, or card
x1 coins None x1 bombs
Needs to be unlocked x1 coins
Needs to be unlocked Store Key Store Key
Starting Item Icon.png Starting Item(s) Needs to be unlocked The D6 The D6 Yum Heart Yum Heart Lucky Foot Lucky Foot The Book of Belial The Book of Belial The Poop The Poop Whore of Babylon Whore of Babylon

Dead Bird Dead Bird

Added in Afterbirth Needs to be unlocked Razor Blade Razor Blade
Bloody Lust Bloody Lust Short range Brimstone Brimstone

Added in Afterbirth † Needs to be unlocked Anemic Anemic Random active item

Random passive item

Spectral tears

D4 D4

Added in Afterbirth Needs to be unlocked Holy Mantle Holy Mantle
Blindfolded App.png Blindfolded

Incubus Incubus

Needs to be unlocked Cambion Conception Cambion Conception

Box of Friends Box of Friends
Triple shot

Needs to be unlocked Wooden Nickel Wooden Nickel
Void Void
Boss Rush Isaac's Head Maggy's Bow Cain's Other Eye Judas' Shadow ???'s Only Friend Eve's Mascara Samson's Chains The Nail Missing No. Undefined The D100 Immaculate Conception Sticky Nickels Locust of Conquest
Hard Mode only Mom's Heart
Lost Baby
Cute Baby
Glass Baby
Shadow Baby
Dead Baby
Crow Baby
Fighting Baby
Wrapped Baby
Begotten Baby
Glitch Baby
-0- Baby
Goat Head Baby
Super Greed Baby
Achievement Smelter icon.png
Satan Mom's Knife Guardian Angel A Bag of Bombs Judas' Tongue Forget Me Now The Razor Blood Rights Daemon's Tail Broken Ankh Book of Secrets The Mind Serpent's Kiss Store Key Locust of Pestilence
Isaac Isaac's Tears A Cross A Bag of Pennies Guillotine The D6 Eve's Bird Foot Bloody Lust Satanic Bible Lazarus' Rags Blank Card Isaac's Heart Rune Bag Wooden Nickel Locust of Wrath
The Lamb Missing Poster Maggy's Faith Abel Curved Horn ???'s Soul Black Lipstick Samson's Lock Demon Baby Pandora's Box Mystery Sack The Soul Succubus Karma Locust of Death
??? The D20 Celtic Cross Cain's Eye The Left Hand Fate Sacrificial Dagger Blood Penny Abaddon Store Credit Mysterious Paper The Body Cambion Conception Deep Pockets Locust of Famine
Greed Mode Ultra Greed Added in Afterbirth Lil' Chest Censer Evil Eye My Shadow Cracked Dice Black Feather Lusty Blood Lilith Key Bum GB Bug Zodiac Box of Friends Rib of Greed Brown Nugget
Hard Greed Mode Ultra Greedier Added in Afterbirth † D1 Glyph of Balance Sack of Sacks Eye of Belial Meconium Crow Heart Stem Cell Bat Wing Plan C Metronome Dad's Lost Coin Duality Eye of Greed Black Rune
Hush Added in Afterbirth Fart Baby Purity D12 Betrayal Fate's Reward Athame Blind Rage Maw of the Void Empty Vessel Eden's Blessing Sworn Protector Incubus Keeper now holds... A Penny! Hushy
Delirium Added in Afterbirth † D Infinity Eucharist Silver Dollar Shade King Baby Dull Razor Bloody Crown Dark Prince's Crown Compound Fracture Eden's Soul Holy Card Euthanasia Crooked Penny Void
Mega Satan Added in Afterbirth Cry Baby Red Baby Green Baby Brown Baby Blue Baby Lil' Baby Rage Baby Black Baby Long Baby Yellow Baby White Baby Big Baby Noose Baby Mort Baby
Hard Mode only All Marks completed Added in Afterbirth Buddy Baby Colorful Baby Picky Baby Belial Baby Hive Baby Whore Baby Revenge Baby Sucky Baby Dripping Baby Cracked Baby Godhead Dark Baby Sale Baby Apollyon Baby


Each character is unlocked by accomplishing a certain task in the game. The unlock requirements are as follows:

Character Unlock requirement
Isaac None; unlocked by default
Magdalene Magdalene Have 7 or more heart containers at one time
Cain Cain Hold 55 coins at one time
Judas Judas Defeat Satan for the 1st time
??? ??? Defeat Mom's Heart 10 times
Eve Eve Don't pick up any hearts for 2 floors in a row
Samson Samson Beat 2 floors in a row without taking damage
Azazel Azazel Make 3 deals with the devil in one run
Lazarus Lazarus Have 4 or more soul hearts at one time
Eden Eden Beat chapter 4 for the 1st time
The Lost The Lost Removed in Afterbirth It's complicated
Added in Afterbirth Die in a Sacrifice Room while holding Missing Poster
Added in Afterbirth Lilith Lilith Added in Afterbirth Defeat Ultra Greed as Azazel
Added in Afterbirth Keeper Keeper Added in Afterbirth Donate 1000 coins to the Greed Machine
Added in Afterbirth † Apollyon None; unlocked by default with Afterbirth †

 Switch  Defeat Mega Satan.


  • One common theory (which was confirmed by Edmund) is that all characters are different forms of Isaac himself. This theory suggests that every character is a creation of Isaac's imagination which he assumes the personality and appearance of when playing as them. Most characters represent different issues that Isaac believes he has, while ??? is Isaac after dying by suffocation inside The Chest, Azazel is who Isaac sees himself as, and The Lost is Isaac's wandering soul (which can be seen upon dying).
    • Added in Afterbirth Additionally, Keeper is Isaac's desiccated corpse, as evidenced by ending 18.

Rebirth Afterbirth Afterbirth †

Isaac CharNav.png Magdalene CharNav.png Cain CharNav.png Judas CharNav.png BlueBaby CharNav.png Eve CharNav.png Samson CharNav.png Azazel CharNav.png Lazarus CharNav.png Eden CharNav.png Lost CharNav.png

Lilith CharNav.png Keeper CharNav.png

Apollyon CharNav.png

SmallIsaac.png The Binding of Isaac: Rebirth SmallIsaac.png

MainPageAchievements.png Achievements MainPageAttributes.png Attributes MainPageBosses.png Bosses TarotCard.png Cards and Runes MainPageChallenges.png Challenges MainPageChapters.png Chapters
Isaac App.png Characters MainPageBabies.png Co-op Magic Mushroom Icon.png Items Isaac's Tears Icon.png Item Pools MainPageMonsters.png Monsters MainPageObjects.png Objects
Red heart.png Pickups BlueBlue.png Pills MainPageRooms.png Rooms MainPageSeeds2.png Seeds Guppy App.png Transformations The Left Hand Icon.png Trinkets
Promotional Content