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Disambig.png This article is about the main player character. For the additional multiplayer characters, see Babies. For non-player characters, see NPCs.

There are eleven playable characters in The Binding of Isaac: Rebirth with three extra characters in the DLCs. Five of these characters (Isaac, Magdalene, Cain, Judas, and ???/Blue Baby) came with the original Binding of Isaac, while two additional characters (Eve and Samson) were added later. Eve was added in the Binding of Isaac's Halloween Update, while Samson was added in The Wrath of the Lamb expansion. Rebirth contains four new characters (Azazel, Lazarus, Eden, and The Lost). In the Afterbirth expansion for Rebirth, one new character (Lilith) was added, plus one more character via an update (Keeper). In the Afterbirth † expansion for Rebirth one character (Apollyon) was added. Each character starts with different stats and abilities that give them their own unique play style.

Each character's progress can be gauged by checking their completion marks.

Rebirth Afterbirth Afterbirth †
Character Isaac App.png
Magdalene App.png
Cain App.png
Judas App.png
Blue Baby App.png
Eve App.png
Samson App.png
Azazel App.png
Lazarus App.png
Eden App.png
The Lost App.png
The Lost
Lilith App.png
Keeper App.png
Apollyon App.png
Health Stat Icon.png Health HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Red Heart.png HUD Red Heart.png HUD Soul Heart.pngHUD Soul Heart.pngHUD Soul Heart.png (no heart containers) HUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Black Heart.pngHUD Black Heart.pngHUD Black Heart.png HUD Red Heart.pngHUD Red Heart.pngHUD Red Heart.png HUD Red Heart.pngHUD Soul Heart.pngHUD Red Heart.png
(Random, up to 3 total)
No health HUD Red Heart.pngHUD Black Heart.pngHUD Black Heart.png HUD Coin Heart.pngHUD Coin Heart.png HUD Red Heart.pngHUD Red Heart.png
Damage Stat Icon.png Damage 3.5 (*1.00) 3.5 (*1.00) 3.5 (*1.20) 3.5 (*1.35) 3.5 (*1.05) 3.5 (*0.75)
(*1.00 at HUD Red Heart.png)
3.5 (*1.00) 3.5 (*1.50) 3.5 (*1.00) 3.5
3.5 (*1.00) 3.5 (*1.00) 3.5 (*1.20) 3.5 (*1.00)
Tears Stat Icon.png Tears +0 +0 +0 +0 +0 +0 -0.05 +0.5, *1/3 +0 ±0.75 +0 +0 +0
Shot Speed Stat Icon.png Shot Speed 1 1 1 1 1 1 1.31 1 1 1 ± 0.25 1 1 1 1
Range Stat Icon.png Range 23.75 23.75 17.75 23.75 23.75 23.75 18.75 17.75 17.75 23.75 ± 5.00 23.75 23.75 23.75 23.75
Speed Stat Icon.png Speed 1.0 0.85 1.3 1.0 1.1 1.23 1.1 1.25 1.0 1.0 ± 0.15 1.0 1.0 0.85 1.0
Luck Stat Icon.png Luck 0 0 0 0 0 0 0 0 -1 0 ± 1 0 0 -2 0
Starting Item Icon.png Starting Pickup(s) x1 bombs Dlc a† Indicator.png Needs to be unlocked x1 Speed Up pill x1 keys,
Dlc a Indicator.png Needs to be unlocked Paper Clip Paper Clip
x3 coins None None Dlc a† Indicator.png Needs to be unlocked Child's Heart Child's Heart 0 - The Fool 0 - The Fool x1 pills x0-2 bombs
x0-1 keys
x0-5 coins
x0-1 trinket, pill, or card
x1 coins None x1 bombs
Needs to be unlocked x1 coins
Needs to be unlocked Store Key Store Key
Starting Item Icon.png Starting Item(s) Needs to be unlocked The D6 The D6 Yum Heart Yum Heart Lucky Foot Lucky Foot The Book of Belial The Book of Belial The Poop The Poop Whore of Babylon Whore of Babylon

Dead Bird Dead Bird

Dlc a Indicator.png Needs to be unlocked Razor Blade Razor Blade
Bloody Lust Bloody Lust Short range Brimstone Brimstone

Dlc a† Indicator.png Needs to be unlocked Anemic Anemic Random active item

Random passive item

Spectral tears

D4 D4

Dlc a Indicator.png Needs to be unlocked Holy Mantle Holy Mantle
Blindfolded App.png Blindfolded

Incubus Incubus

Needs to be unlocked Cambion Conception Cambion Conception

Box of Friends Box of Friends
Triple shot

Needs to be unlocked Wooden Nickel Wooden Nickel
Void Void
Boss Rush
Achievement isaac's head.png
Achievement maggy's bow.png
Achievement cain's other eye.png
Achievement judas' shadow.png
Achievement blue babys only friend.png
Achievement eve's mascara.png
Achievement samson's chains.png
Achievement the nail.png
Achievement missing no..png
Achievement undefined.png
Achievement a d100.png
Achievement immaculate conception.png
Achievement sticky nickels.png
Achievement locust of conquest.png
Hard Mode only Mom's Heart
Lost Baby
Cute Baby
Glass Baby
Shadow Baby
Dead Baby
Crow Baby
Fighting Baby
Wrapped Baby
Begotten Baby
Glitch Baby
-0- Baby
Goat Head Baby
Super Greed Baby
Achievement smelter.png
Achievement mom's knife.png
Achievement guardian angel.png
Achievement a bag of bombs.png
Achievement judas' tongue.png
Achievement a forget me now.png
Achievement the razor.png
Achievement blood rights.png
Achievement daemon's tail.png
Achievement broken ankh.png
Achievement book of secrets.png
Achievement the mind.png
Achievement serpent's kiss.png
Achievement keeper now holds store key.png
Achievement locust of pestilence.png
Achievement isaac's tears.png
Achievement a cross.png
Achievement a bag of pennies.png
Achievement guillotine.png
Achievement the d6.png
Achievement eve's bird foot.png
Achievement blood lust.png
Achievement satanic bible.png
Achievement lazarus' rags.png
Achievement blank card.png
Achievement isaac's heart.png
Achievement rune bag.png
Achievement keepers wooden nickel.png
Achievement locust of wrath.png
The Lamb
Achievement the lost poster.png
Achievement maggy's faith.png
Achievement abel.png
Achievement curved horn.png
Achievement blue babys soul.png
Achievement black lipstick.png
Achievement samson's lock.png
Achievement a demon baby!.png
Achievement pandora's box.png
Achievement mystery sack.png
Achievement the soul.png
Achievement succubus.png
Achievement karma.png
Achievement locust of death.png
Achievement the d20.png
Achievement the crucifix.png
Achievement cain's eye.png
Achievement the left hand.png
Achievement fate.png
Achievement sacrificial dagger.png
Achievement blood penny.png
Achievement abaddon.png
Achievement store credit.png
Achievement mysterious paper.png
Achievement the body.png
Achievement cambion conception.png
Achievement deep pockets.png
Achievement locust of famine.png
Greed Mode Ultra Greed Dlc a Indicator.png
Achievement lil' chest.png
Achievement censer.png
Achievement evil eye.png
Achievement my shadow.png
Achievement cracked dice.png
Achievement black feather.png
Achievement lusty blood.png
Achievement lilith.png
Achievement key bum.png
Achievement gb bug.png
Achievement zodiac.png
Achievement box of friends.png
Achievement rib of greed.png
Achievement brown nugget.png
Hard Greed Mode Ultra Greedier Dlc a† Indicator.png
Achievement d1.png
Achievement glyph of balance.png
Achievement sack of sacks.png
Achievement eye of belial.png
Achievement meconium.png
Achievement crow heart.png
Achievement stem cell.png
Achievement bat wing.png
Achievement plan c.png
Achievement metronome.png
Achievement dad's lost coin.png
Achievement duality.png
Achievement eye of greed.png
Black Rune
Hush Dlc a Indicator.png
Achievement fart baby.png
Achievement purity.png
Achievement d12.png
Achievement betrayal.png
Achievement fate's reward.png
Achievement athame.png
Achievement blind rage.png
Achievement maw of the void.png
Achievement empty vessel.png
Achievement eden's blessing.png
Achievement sworn protector.png
Achievement incubus.png
Keeper now Holds a Penny
Achievement hushy.png
Delirium Dlc a† Indicator.png
Achievement d infinity.png
Achievement eucharist.png
Achievement silver dollar.png
Achievement shade.png
Achievement king baby.png
Achievement dull razor.png
Achievement bloody crown.png
Achievement dark prince's crown.png
Achievement compound fracture.png
Achievement eden's soul.png
Achievement holy card.png
Achievement euthanasia.png
Achievement crooked penny.png
Achievement void.png
Mega Satan Dlc a Indicator.png
Cry Baby
Red Baby
Green Baby
Brown Baby
Blue Baby
Lil' Baby
Rage Baby
Black Baby
Long Baby
Yellow Baby
White Baby
Big Baby
Noose Baby
Mort Baby
Hard Mode only All Marks completed Dlc a Indicator.png
Buddy Baby
Colorful Baby
Picky Baby
Belial Baby
Hive Baby
Whore Baby
Revenge Baby
Sucky Baby
Dripping Baby
Cracked Baby
Achievement godhead.png
Dark Baby
Sale Baby
Apollyon Baby


Each character is unlocked by accomplishing a certain task in the game. The unlock requirements are as follows:

Character Unlock requirement
Isaac None; unlocked by default
Magdalene Magdalene Have 7 or more heart containers at one time
Cain Cain Hold 55 coins at one time
Judas Judas Defeat Satan for the 1st time
??? ??? Defeat Mom's Heart 10 times
Eve Eve Don't pick up any hearts for 2 floors in a row
Samson Samson Beat 2 floors in a row without taking damage
Azazel Azazel Make 3 deals with the devil in one run
Lazarus Lazarus Have 4 or more soul hearts at one time
Eden Eden Beat chapter 4 for the 1st time
The Lost The Lost Dlc na Indicator.png It's complicated
Dlc a Indicator.png Die in a Sacrifice Room while holding Missing Poster
Dlc a Indicator.png Lilith Lilith Dlc a Indicator.png Defeat Ultra Greed as Azazel
Dlc a Indicator.png Keeper Keeper Dlc a Indicator.png Donate 1000 coins to the Greed Machine
Dlc a† Indicator.png Apollyon None; unlocked by default with Afterbirth †

 Switch  Defeat Mega Satan.


  • One common theory (which was confirmed by Edmund) is that all characters are different forms of Isaac himself. This theory suggests that every character is a creation of Isaac's imagination which he assumes the personality and appearance of when playing as them. Most characters represent different issues that Isaac believes he has, while ??? is Isaac after dying by suffocation inside The Chest, Azazel is who Isaac sees himself as, and The Lost is Isaac's wandering soul (which can be seen upon dying).
    • Dlc a Indicator.png Additionally, Keeper is Isaac's desiccated corpse, as evidenced by ending 18.

Rebirth Afterbirth Afterbirth †

Isaac CharNav.png Magdalene CharNav.png Cain CharNav.png Judas CharNav.png BlueBaby CharNav.png Eve CharNav.png Samson CharNav.png Azazel CharNav.png Lazarus CharNav.png Eden CharNav.png Lost CharNav.png

Lilith CharNav.png Keeper CharNav.png

Apollyon CharNav.png

SmallIsaac.png The Binding of Isaac: Rebirth SmallIsaac.png

MainPageAchievements.png Achievements MainPageAttributes.png Attributes MainPageBosses.png Bosses TarotCard.png Cards and Runes MainPageChallenges.png Challenges MainPageChapters.png Chapters
Isaac App.png Characters MainPageBabies.png Co-op Magic Mushroom Icon.png Items Isaac's Tears Icon.png Item Pools MainPageMonsters.png Monsters MainPageObjects.png Objects
Red heart.png Pickups BlueBlue.png Pills MainPageRooms.png Rooms MainPageSeeds2.png Seeds Guppy App.png Transformations The Left Hand Icon.png Trinkets