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Characters

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Disambig.png This article is about the main player character. For the additional multiplayer characters, see Babies. For non-player characters, see NPCs.

There are eleven playable characters in The Binding of Isaac: Rebirth with four extra characters in the DLCs. Five of these characters (Isaac, Magdalene, Cain, Judas, and ???/Blue Baby) came with the original Binding of Isaac, while two additional characters (Eve and Samson) were added later. Eve was added in the Binding of Isaac's Halloween Update, while Samson was added in The Wrath of the Lamb expansion. Rebirth contains four new characters (Azazel, Lazarus, Eden, and The Lost). In the Afterbirth expansion for Rebirth, one new character (Lilith) was added, plus one more character via an update (Keeper). In the Afterbirth † expansion for Rebirth one character (Apollyon) was added, plus one more secret character (The Forgotten) added via a Booster Pack. Each character starts with different stats and abilities that give them their own unique play style.

Each character's progress can be gauged by checking their completion marks.

Rebirth Afterbirth Afterbirth †
Character Isaac App.png
Isaac
Magdalene App.png
Magdalene
Cain App.png
Cain
Judas App.png
Judas
Blue Baby App.png
???
Eve App.png
Eve
Samson App.png
Samson
Azazel App.png
Azazel
Lazarus App.png
Lazarus
Eden App.png
Eden
The Lost App.png
The Lost
Lilith App.png
Lilith
Keeper App.png
Keeper
Apollyon App.png
Apollyon
The Forgotten App.png
The Forgotten
Judas Dark Judas Lazarus Lazarus Risen The Forgotten The Soul
Health Stat Icon.png Health Full red heartFull red heartFull red heart Full red heartFull red heartFull red heartFull red heart Full red heartFull red heart Full red heart Full black heartFull black heart Full soul heartFull soul heartFull soul heart Full red heartFull red heart Full red heartFull red heartFull red heart Full black heartFull black heartFull black heart Full red heartFull red heartFull red heart Full red heart Random No health Full red heartFull black heartFull black heart Full coin heartFull coin heart Full red heartFull red heart Full bone heartFull bone heart Full soul heart
Damage Stat Icon.png Damage 3.5 (*1.00) 3.5 (*1.00) 3.5 (*1.20) 3.5 (*1.35) 3.5 (*2.00) 3.5 (*1.05) 3.5 (*0.75)
(*1.00 at Full red heart)
3.5 (*1.00) 3.5 (*1.50) 3.5 (*1.00) 3.5 (*1.20) 3.5
(*1.00)
±1.00
3.5 (*1.00) 3.5 (*1.00) 3.5 (*1.20) 3.5 (*1.00) 3.5 (*1.50) 3.5 (*1.00)
Tears Stat Icon.png Tears +0 +0 +0 +0 +0 +0 +0 -0.05 +0.5, *1/3 +0 +0 ±0.75 +0 +0 +18 +0 +0 +0
Shot Speed Stat Icon.png Shot Speed 1 1 1 1 1 1 1 1.31 1 1 1 1 ± 0.25 1 1 1 1 1 1
Range Stat Icon.png Range 23.75 23.75 17.75 23.75 23.75 23.75 23.75 18.75 17.75 17.75 23.75 23.75 ± 5.00 23.75 23.75 23.75 23.75 23.75 23.75
Speed Stat Icon.png Speed 1.0 0.85 1.3 1.0 1.1 1.1 1.23 1.1 1.25 1.0 1.25 1.0 ± 0.15 1.0 1.0 0.85 1.0 1.0 1.3
Luck Stat Icon.png Luck 0 0 0 0 0 0 0 0 0 -1 0 0 ± 1 0 0 -2 0 0 0
Starting Item Icon.png Starting Pickup(s) x1 bombs Added in Afterbirth † Needs to be unlocked x1 Speed Up pill x1 keys,
Added in Afterbirth Needs to be unlocked Paper Clip Paper ClipPaper Clip Icon.pngGolden Chests can be opened without using a key.
x3 coins None None None Added in Afterbirth † Needs to be unlocked Child's Heart Child's HeartChild's Heart Icon.pngIncreases the chance of a Heart dropping after clearing a room, and the chance of finding a Heart when opening a Chest. 0 - The Fool 0 - The Fool0 - The Fool Icon.pngTeleports Isaac back to the starting room of a floor. x1 pills None x0-2 bombs
x0-1 keys
x0-5 coins
x0-1 trinket, pill, or card
x1 coins None x1 bombs
Needs to be unlocked x1 coins
Needs to be unlocked Added in AfterbirthStore Key Store KeyStore Key Icon.pngAutomatically opens all Shops.
None None
Starting Item Icon.png Starting Item(s) Needs to be unlocked The D6 The D6The D6 Icon.png6 roomsAllows Isaac to re-roll collectible items in the current room into other items, depending on the current room's Item Pool. Yum Heart Yum HeartYum Heart Icon.png4 roomsRestores 1 whole red heart. Lucky Foot Lucky FootLucky Foot Icon.png+1 Luck. Increases chance of winning Shell Game Beggar. (Independent of luck stat) The Book of Belial The Book of BelialThe Book of Belial Icon.png3 roomsUpon use increases damage by 2 for the current room and by a further +50% if the character also has the Blood of the Martyr.
Removed in Afterbirth Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it, or Added in Afterbirth increases the chance by 12.5%.
None The Poop The PoopThe Poop Icon.png1 roomsSpawns a pile of poop where the character is standing and knocks nearby monsters back. May yield pickups like regular poop. Whore of Babylon Whore of BabylonWhore of Babylon Icon.pngIncreases damage and speed whenever Isaac has half a red heart or less (one red heart for Eve), ignoring any soul or black hearts.

Dead Bird Dead BirdDead Bird Icon.pngSpawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.

Added in Afterbirth Needs to be unlocked Razor Blade Razor BladeRazor Blade Icon.pngUnlimitedUpon use, deals one heart of damage to Isaac and grants +1.2 damage for the current room.
Bloody Lust Bloody LustBloody Lust Icon.pngIncreases damage as Isaac receives damage. Damage increase stays for the whole floor. Short range Brimstone BrimstoneBrimstone Icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.

Flight
Added in Afterbirth † Needs to be unlocked Anemic AnemicAnemic Icon.png+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room. Anemic AnemicAnemic Icon.png+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room. Random active item

Random passive item
Flight

Added in Afterbirth Spectral tears

Added in Afterbirth D4 D4D4 Icon.png6 roomsRerolls all of Isaac's items.

Added in Afterbirth Needs to be unlocked Holy Mantle Holy MantleHoly Mantle Icon.pngAutomatically negates first taken damage in every room.
Blindfolded.png Blindfolded

Added in AfterbirthIncubus IncubusIncubus Icon.pngA demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects.

Added in AfterbirthCambion Conception Cambion ConceptionCambion Conception Icon.pngAfter taking damage a certain amount of times, a permanent demonic familiar spawns.

Added in AfterbirthBox of Friends Box of FriendsBox of Friends Icon.png4 roomsUpon use, duplicates all of Isaac's familiars for the current room.
Triple shot

Needs to be unlocked Added in AfterbirthWooden Nickel Wooden NickelWooden Nickel Icon.png1 roomsWhen used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).
Added in Afterbirth †Void VoidVoid Icon.png6 roomsConsumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades. None
Achievements
Boss Rush Isaac's Head Isaac's HeadIsaac's HeadComplete the Boss Rush as Isaac Maggy's Bow Maggy's BowMaggy's BowComplete the Boss Rush as Magdalene Cain's Other Eye Cain's Other EyeCain's Other EyeComplete the Boss Rush as Cain Judas' Shadow Judas' ShadowJudas' ShadowComplete the Boss Rush as Judas ???'s Only Friend ???'s Only Friend???'s Only FriendComplete the Boss Rush as ??? Eve's Mascara Eve's MascaraEve's MascaraComplete the Boss Rush as Eve Samson's Chains Samson's ChainsSamson's ChainsComplete the Boss Rush as Samson The Nail The NailThe NailComplete the Boss Rush as Azazel Missing No. Missing No.Missing No.Complete the Boss Rush as Lazarus Undefined UndefinedUndefinedComplete the Boss Rush as Eden The D100 The D100The D100Complete the Boss Rush as The Lost Added in AfterbirthImmaculate Conception Immaculate ConceptionImmaculate ConceptionComplete the Boss Rush as Lilith Added in AfterbirthSticky Nickels Sticky NickelsSticky NickelsComplete the Boss Rush as Keeper Added in Afterbirth †Locust of Conquest Locust of ConquestLocust of ConquestComplete the Boss Rush as Apollyon Added in Afterbirth †Divorce Papers Divorce PapersDivorce PapersComplete the Boss Rush as The Forgotten
Hard mode only Mom's Heart Lost Baby Lost BabyLost BabyDefeat Mom's Heart on hard mode as Isaac Cute Baby Cute BabyCute BabyDefeat Mom's Heart on hard mode as Magdalene Glass Baby Glass BabyGlass BabyDefeat Mom's Heart on hard mode as Cain Shadow Baby Shadow BabyShadow BabyDefeat Mom's Heart on hard mode as Judas Dead Baby Dead BabyDead BabyDefeat Mom's Heart on hard mode as ??? Crow Baby Crow BabyCrow BabyDefeat Mom's Heart on hard mode as Eve Fighting Baby Fighting BabyFighting BabyDefeat Mom's Heart on hard mode as Samson Begotten Baby Begotten BabyBegotten BabyRemoved in Afterbirth † Defeat Mom's Heart on hard mode as Lazarus
Added in Afterbirth † Defeat Mom's Heart on hard mode as Azazel
Wrapped Baby Wrapped BabyWrapped BabyRemoved in Afterbirth † Defeat Mom's Heart on hard mode as Azazel
Added in Afterbirth † Defeat Mom's Heart on hard mode as Lazarus
Glitch Baby Glitch BabyGlitch BabyDefeat Mom's Heart on hard mode as Eden -0- Baby -0- Baby-0- BabyDefeat Mom's Heart on hard mode as The Lost Added in AfterbirthGoat Head Baby Goat Head BabyGoat Head BabyDefeat Mom's Heart on hard mode as Lilith Added in AfterbirthSuper Greed Baby Super Greed BabySuper Greed BabyDefeat Mom's Heart on hard mode as Keeper Added in Afterbirth †Smelter SmelterSmelterDefeat Mom's Heart or It Lives! on hard mode as Apollyon Added in Afterbirth †Marrow MarrowMarrowDefeat Mom's Heart or It Lives! on hard mode as The Forgotten
Satan Mom's Knife Mom's KnifeMom's KnifeDefeat Satan as Isaac Guardian Angel Guardian AngelGuardian AngelDefeat Satan as Magdalene A Bag of Bombs A Bag of BombsA Bag of BombsDefeat Satan as Cain Judas' Tongue Judas' TongueJudas' TongueDefeat Satan as Judas Forget Me Now Forget Me NowForget Me NowDefeat Satan as ??? The Razor The RazorThe RazorDefeat Satan as Eve Blood Rights Blood RightsBlood RightsDefeat Satan as Samson Daemon's Tail Daemon's TailDaemon's TailDefeat Satan as Azazel Broken Ankh Broken AnkhBroken AnkhDefeat Satan as Lazarus Book of Secrets Book of SecretsBook of SecretsDefeat Satan as Eden The Mind The MindThe MindDefeat Satan as The Lost Added in AfterbirthSerpent's Kiss Serpent's KissSerpent's KissDefeat Satan as Lilith Added in AfterbirthKeeper holds Store Key Keeper holds Store KeyKeeper holds Store KeyDefeat Satan as Keeper Added in Afterbirth †Locust of Pestilence Locust of PestilenceLocust of PestilenceDefeat Satan as Apollyon Added in Afterbirth †Pointy Rib Pointy RibPointy RibDefeat Satan as The Forgotten
Isaac Isaac's Tears Isaac's TearsIsaac's TearsDefeat Isaac as Isaac A Cross A CrossA CrossDefeat Isaac as Magdalene A Bag of Pennies A Bag of PenniesA Bag of PenniesDefeat Isaac as Cain Guillotine GuillotineGuillotineDefeat Isaac as Judas The D6 The D6The D6Defeat Isaac as ??? Eve's Bird Foot Eve's Bird FootEve's Bird FootDefeat Isaac as Eve Bloody Lust Bloody LustBloody LustDefeat Isaac as Samson Satanic Bible Satanic BibleSatanic BibleDefeat Isaac as Azazel Lazarus' Rags Lazarus' RagsLazarus' RagsDefeat Isaac as Lazarus Blank Card Blank CardBlank CardDefeat Isaac as Eden Isaac's Heart Isaac's HeartIsaac's HeartDefeat Isaac as The Lost Added in AfterbirthRune Bag Rune BagRune BagDefeat Isaac as Lilith Added in AfterbirthKeeper holds Wooden Nickel Keeper holds Wooden NickelKeeper holds Wooden NickelDefeat Isaac as Keeper Added in Afterbirth †Locust of Wrath Locust of WarLocust of WrathDefeat Isaac as Apollyon Added in Afterbirth †Slipped Rib Slipped RibSlipped RibDefeat Isaac as The Forgotten
The Lamb Missing Poster Missing PosterMissing PosterDefeat The Lamb as Isaac Maggy's Faith Maggy's FaithMaggy's FaithDefeat The Lamb as Magdalene Abel AbelAbelDefeat The Lamb as Cain Curved Horn Curved HornCurved HornDefeat The Lamb as Judas ???'s Soul ???'s Soul???'s SoulDefeat The Lamb as ??? Black Lipstick Black LipstickBlack LipstickDefeat The Lamb as Eve Samson's Lock Samson's LockSamson's LockDefeat The Lamb as Samson Demon Baby Demon BabyDemon BabyDefeat The Lamb as Azazel Pandora's Box Pandora's BoxPandora's BoxDefeat The Lamb as Lazarus Mystery Sack Mystery SackMystery SackDefeat The Lamb as Eden The Soul The SoulThe SoulDefeat The Lamb as The Lost Added in AfterbirthSuccubus SuccubusSuccubusDefeat The Lamb as Lilith Added in AfterbirthKarma KarmaKarmaDefeat The Lamb as Keeper Added in Afterbirth †Locust of Death Locust of DeathLocust of DeathDefeat The Lamb as Apollyon Added in Afterbirth †Brittle Bones Brittle BonesBrittle BonesDefeat The Lamb as The Forgotten
??? The D20 The D20The D20Defeat ??? as Isaac Celtic Cross Celtic CrossCeltic CrossDefeat ??? as Magdalene Cain's Eye Cain's EyeCain's EyeDefeat ??? as Cain The Left Hand The Left HandThe Left HandDefeat Ultra Pride or ??? as Judas Fate FateFateDefeat ??? as ??? Sacrificial Dagger Sacrificial DaggerSacrificial DaggerDefeat ??? as Eve Blood Penny Blood PennyBlood PennyDefeat ??? as Samson Abaddon AbaddonAbaddonDefeat ??? as Azazel Store Credit Store CreditStore CreditDefeat ??? as Lazarus Mysterious Paper Mysterious PaperMysterious PaperBeat ??? as Eden The Body The BodyThe BodyDefeat ??? as The Lost Added in AfterbirthCambion Conception Cambion ConceptionCambion ConceptionDefeat ??? as Lilith Added in AfterbirthDeep Pockets Deep PocketsDeep PocketsDefeat ??? as Keeper Added in Afterbirth †Locust of Famine Locust of FamineLocust of FamineDefeat ??? as Apollyon Added in Afterbirth †Jaw Bone Jaw BoneJaw BoneDefeat ??? as The Forgotten
Greed mode only Ultra Greed Added in Afterbirth Added in AfterbirthLil' Chest Lil' ChestLil' ChestDefeat Ultra Greed as Isaac Added in AfterbirthCenser CenserCenserDefeat Ultra Greed as Magdalene Added in AfterbirthEvil Eye Evil EyeEvil EyeDefeat Ultra Greed as Cain Added in AfterbirthMy Shadow My ShadowMy ShadowDefeat Ultra Greed as Judas Added in AfterbirthCracked Dice Cracked DiceCracked DiceDefeat Ultra Greed as ??? Added in AfterbirthBlack Feather Black FeatherBlack FeatherDefeat Ultra Greed as Eve Added in AfterbirthLusty Blood Lusty BloodLusty BloodDefeat Ultra Greed as Samson Added in AfterbirthLilith LilithLilithDefeat Ultra Greed as Azazel Added in AfterbirthKey Bum Key BumKey BumDefeat Ultra Greed as Lazarus Added in AfterbirthGB Bug GB BugGB BugDefeat Ultra Greed as Eden Added in AfterbirthZodiac ZodiacZodiacDefeat Ultra Greed as The Lost Added in AfterbirthBox of Friends Box of FriendsBox of FriendsDefeat Ultra Greed as Lilith Added in AfterbirthRib of Greed Rib of GreedRib of GreedDefeat Ultra Greed as Keeper Added in Afterbirth †Brown Nugget Brown NuggetBrown NuggetDefeat Ultra Greed as Apollyon Added in Afterbirth †Finger Bone Finger BoneFinger BoneDefeat Ultra Greed as The Forgotten
Greedier mode only Ultra Greedier Added in Afterbirth † Added in Afterbirth †D1 D1D1Defeat Ultra Greedier as Isaac Added in Afterbirth †Glyph of Balance Glyph of BalanceGlyph of BalanceDefeat Ultra Greedier as Magdalene Added in Afterbirth †Sack of Sacks Sack of SacksSack of SacksDefeat Ultra Greedier as Cain Added in Afterbirth †Eye of Belial Eye of BelialEye of BelialDefeat Ultra Greedier as Judas Added in Afterbirth †Meconium MeconiumMeconiumDefeat Ultra Greedier as ??? Added in Afterbirth †Crow Heart Crow HeartCrow HeartDefeat Ultra Greedier as Eve Added in Afterbirth †Stem Cell Stem CellStem CellDefeat Ultra Greedier as Samson Added in Afterbirth †Bat Wing Bat WingBat WingDefeat Ultra Greedier as Azazel Added in Afterbirth †Plan C Plan CPlan CDefeat Ultra Greedier as Lazarus Added in Afterbirth †Metronome MetronomeMetronomeDefeat Ultra Greedier as Eden Added in Afterbirth †Dad's Lost Coin Dad's Lost CoinDad's Lost CoinDefeat Ultra Greedier as The Lost Added in Afterbirth †Duality DualityDualityDefeat Ultra Greedier as Lilith Added in Afterbirth †Eye of Greed Eye of GreedEye of GreedDefeat Ultra Greedier as Keeper Added in Afterbirth †Black Rune Black RuneBlack RuneDefeat Ultra Greedier as Apollyon Added in Afterbirth †Dad's Ring Dad's RingDad's RingDefeat Ultra Greedier as The Forgotten
Hush Added in Afterbirth Added in AfterbirthFart Baby Fart BabyFart BabyDefeat Hush as Isaac Added in AfterbirthPurity PurityPurityDefeat Hush as Magdalene Added in AfterbirthD12 D12D12Defeat Hush as Cain Added in AfterbirthBetrayal BetrayalBetrayalDefeat Hush as Judas Added in AfterbirthFate's Reward Fate's RewardFate's RewardDefeat Hush as ??? Added in AfterbirthAthame AthameAthameDefeat Hush as Eve Added in AfterbirthBlind Rage Blind RageBlind RageDefeat Hush as Samson Added in AfterbirthMaw of the Void Maw of the VoidMaw of the VoidDefeat Hush as Azazel Added in AfterbirthEmpty Vessel Empty VesselEmpty VesselDefeat Hush as Lazarus Added in AfterbirthEden's Blessing Eden's BlessingEden's BlessingDefeat Hush as Eden Added in AfterbirthSworn Protector Sworn ProtectorSworn ProtectorDefeat Hush as The Lost Added in AfterbirthIncubus IncubusIncubusDefeat Hush as Lilith Added in AfterbirthKeeper now holds... A Penny! Keeper now holds... A Penny!Keeper now holds... A Penny!Defeat Hush as Keeper Added in Afterbirth †Hushy HushyHushyDefeat Hush as Apollyon Added in Afterbirth †Hallowed Ground Hallowed GroundHallowed GroundDefeat Hush as The Forgotten
Delirium Added in Afterbirth † Added in Afterbirth †D Infinity D InfinityD InfinityDefeat Delirium as Isaac Added in Afterbirth †Eucharist EucharistEucharistDefeat Delirium as Magdalene Added in Afterbirth †Silver Dollar Silver DollarSilver DollarDefeat Delirium as Cain Added in Afterbirth †Shade ShadeShadeDefeat Delirium as Judas Added in Afterbirth †King Baby King BabyKing BabyDefeat Delirium as ??? Added in Afterbirth †Dull Razor Dull RazorDull RazorDefeat Delirium as Eve Added in Afterbirth †Bloody Crown Bloody CrownBloody CrownDefeat Delirium as Samson Added in Afterbirth †Dark Prince's Crown Dark Prince's CrownDark Prince's CrownDefeat Delirium as Azazel Added in Afterbirth †Compound Fracture Compound FractureCompound FractureDefeat Delirium as Lazarus Added in Afterbirth †Eden's Soul Eden's SoulEden's SoulDefeat Delirium as Eden Added in Afterbirth †Holy Card Holy CardHoly CardDefeat Delirium as The Lost Added in Afterbirth †Euthanasia EuthanasiaEuthanasiaDefeat Delirium as Lilith Added in Afterbirth †Crooked Penny Crooked PennyCrooked PennyDefeat Delirium as Keeper Added in Afterbirth †Void VoidVoidDefeat Delirium as Apollyon Added in Afterbirth †Book of the Dead Book of the DeadBook of the DeadDefeat Delirium as The Forgotten
Mega Satan Added in Afterbirth Added in AfterbirthCry Baby Cry BabyCry BabyDefeat Mega Satan as Isaac Added in AfterbirthRed Baby Red BabyRed BabyDefeat Mega Satan as Magdalene Added in AfterbirthGreen Baby Green BabyGreen BabyDefeat Mega Satan as Cain Added in AfterbirthBrown Baby Brown BabyBrown BabyDefeat Mega Satan as Judas Added in AfterbirthBlue Baby Blue BabyBlue BabyDefeat Mega Satan as ??? Added in AfterbirthLil' Baby Lil' BabyLil' BabyDefeat Mega Satan as Eve Added in AfterbirthRage Baby Rage BabyRage BabyDefeat Mega Satan as Samson Added in AfterbirthBlack Baby Black BabyBlack BabyDefeat Mega Satan as Azazel Added in AfterbirthLong Baby Long BabyLong BabyDefeat Mega Satan as Lazarus Added in AfterbirthYellow Baby Yellow BabyYellow BabyDefeat Mega Satan as Eden Added in AfterbirthWhite Baby White BabyWhite BabyDefeat Mega Satan as The Lost Added in AfterbirthBig Baby Big BabyBig BabyDefeat Mega Satan as Lilith Added in AfterbirthNoose Baby Noose BabyNoose BabyDefeat Mega Satan as Keeper Added in Afterbirth †Mort Baby Mort BabyMort BabyDefeat Mega Satan as Apollyon Added in Afterbirth †Bound Baby Bound BabyBound BabyDefeat Mega Satan as The Forgotten
Hard mode only All Marks completed Added in Afterbirth Added in AfterbirthBuddy Baby Buddy BabyBuddy BabyEarn all hard mode completion marks as Isaac Added in AfterbirthColorful Baby Colorful BabyColorful BabyEarn all hard mode completion marks as Magdalene Added in AfterbirthPicky Baby Picky BabyPicky BabyEarn all hard mode completion marks as Cain Added in AfterbirthBelial Baby Belial BabyBelial BabyEarn all hard mode completion marks as Judas Added in AfterbirthHive Baby Hive BabyHive BabyEarn all hard mode completion marks as ??? Added in AfterbirthWhore Baby Whore BabyWhore BabyEarn all hard mode completion marks as Eve Added in AfterbirthRevenge Baby Revenge BabyRevenge BabyEarn all hard mode completion marks as Samson Added in AfterbirthSucky Baby Sucky BabySucky BabyEarn all hard mode completion marks as Azazel Added in AfterbirthDripping Baby Dripping BabyDripping BabyEarn all hard mode completion marks as Lazarus Added in AfterbirthCracked Baby Cracked BabyCracked BabyEarn all hard mode completion marks as Eden Godhead GodheadGodheadRemoved in Afterbirth Beat Mom's Heart, Isaac, Satan, ???, and The Lamb and complete the Boss Rush on hard mode as The Lost
Added in Afterbirth Earn all 9 Completion Marks on hard mode as The Lost
Added in AfterbirthDark Baby Dark BabyDark BabyEarn all hard mode completion marks as Lilith Added in AfterbirthSale Baby Sale BabySale BabyEarn all hard mode completion marks as Keeper Added in Afterbirth †Apollyon Baby Apollyon BabyApollyon BabyEarn all Hard Mode Completion Marks as Apollyon Added in Afterbirth †Bone Baby Bone BabyBone BabyEarn all Hard Mode Completion Marks as The Forgotten

Unlocking

Each character is unlocked by accomplishing a certain task in the game. The unlock requirements are as follows:

Character Unlock requirement
Isaac None; unlocked by default
Magdalene Magdalene MagdaleneMagdaleneHave 7 or more heart containers at one time
Cain Cain CainCainHold 55 coins at one time
Judas Judas JudasJudasDefeat Satan for the 1st time
??? ??? ??????Defeat Mom's Heart 10 times
Eve Eve EveEveDon't pick up any hearts for 2 floors in a row
Samson Samson SamsonSamsonComplete 2 floors in a row without taking damage
Azazel Azazel AzazelAzazelMake 3 deals with the devil in one run
Lazarus Lazarus LazarusLazarusHave 4 or more soul hearts at one time
Eden Eden EdenEdenComplete chapter 4 for the 1st time
The Lost The Lost The LostThe LostRemoved in Afterbirth It's complicated
Added in Afterbirth Die in a Sacrifice Room while holding Missing Poster
Added in Afterbirth Lilith Added in AfterbirthLilith LilithLilithDefeat Ultra Greed as Azazel
Added in Afterbirth Keeper Added in AfterbirthKeeper KeeperKeeperDonate 1000 coins to the Greed Machine
Added in Afterbirth † Apollyon Added in Afterbirth †Apollyon ApollyonApollyonDefeat Mega Satan for the 1st time
Added in Afterbirth † The Forgotten Added in Afterbirth †The Forgotten The ForgottenThe ForgottenIt's complicated

Trivia

  • One common theory (which was confirmed by Edmund) is that all characters are different forms of Isaac himself. This theory suggests that every character is a creation of Isaac's imagination which he assumes the personality and appearance of when playing as them. Most characters represent different issues that Isaac believes he has, while ??? is Isaac after dying by suffocation inside The Chest, Azazel is who Isaac sees himself as, and The Lost is Isaac's wandering soul (which can be seen upon dying).
    • Added in Afterbirth Additionally, Keeper is Isaac's desiccated corpse, as evidenced by Ending 18.
    • Added in Afterbirth † The Forgotten could be Isaac's skeleton shown in Ending 17 and the Final Ending.


The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets