Closets

Closets are rare, small, dead end rooms added in The Binding of Isaac: Afterbirth. Closets often contain a unique arrangement of objects, pickups, items, or enemies, but are otherwise identical in appearance to normal rooms. Each chapter has a different set of 9-10 closet layouts.

The Basement

• 3 buttons
• A trapdoor to the next floor
• Rag Man
  • A yellow Ragling spawns instead as of Booster Pack #5.
• A bed
• A gold bomb surrounded by TNT
• Lots of urns
• A golden poop and 5 regular piles of poop
• 5 suction pitfalls and 3 red chests
• 3 mega troll bombs and 4 black flies
• A golden key and 2 random pickups behind key blocks
• Several Blue Gapers surrounded by rocks
• A Golden Chest, 4 fireplaces and 2 urns

The Cellar

• 3 buttons
• A bomb bum
• A Black Globin's Head and a Black Globin's Body
• A bed
• A gold bomb surrounded by TNT
• Lots of urns
• A golden poop and 5 regular piles of poop
• 5 suction pitfalls and 3 red chests
• 3 mega troll bombs and 4 spiders
• A golden key and 2 random pickups behind key blocks

The Caves

• A trapdoor to the next floor
• 5 dips surrounded by poop
• 6 coins and a Donation Machine
• 6 coins and a Shell Game Beggar
• 3 piles of black poop, a black heart, and a Devil Beggar
• 3 buttons
• 3 Dark Balls
• A shopkeeper and 18 black flies
• Lots of mushrooms
• A normal beggar and a black fly surrounded by troll bombs
• 5 Bomb Bums surrounded by 12 fireplaces and 6 red fireplaces

The Catacombs

• A trapdoor to the next floor behind spikes
• 5 troll bombs surrounded by poop
• A shopkeeper and an angel chest
• 6 coins and a Shell Game Beggar
• 3 piles of black poop, a black heart, and a Devil Beggar
• 2 buttons, one behind spikes
• 8 boils
• A shopkeeper and 18 black flies
• Lots of mushrooms and poop
• A normal beggar and a black fly surrounded by troll bombs
• 4 keys and an eternal chest in the center

The Depths

• 5 shopkeepers and a random item from the treasure room pool
• 9 keys arranged in the shape of a key
• A troll bomb surrounded by skulls
• 3 buttons, a trapdoor to the next floor, and an I AM ERROR shopkeeper
• A bed
• 8 golden chests behind key blocks
• Polycephalus
• 3 piles of golden poop behind spikes
• One pile of each type of poop
• 4 Chubs at the bottom of the room and a hanging shopkeeper in the center
• 9 Angel Chests surrounded by 5 Purple Fireplaces
• 20 Blue Fireplaces in an “A” formation with a single bomb in the center
• 8 Stone Chests surrounding a skull

Necropolis

• 5 shopkeepers and a random item from the treasure room pool
• 9 keys arranged in the shape of a key
• A troll bomb surrounded by skulls
• 2 buttons, a sack, a trapdoor to the next floor, and an I AM ERROR shopkeeper
• A bed
• 8 golden chests behind key blocks
• A medium-sized Teratoma
• 3 piles of golden poop behind spikes
• One pile of each type of poop

The Womb

• 19 boils
• 6 boils and 6 brown chests behind key blocks
• 2 Gluttonies
• 3 spike chests behind spikes and retractable spikes
• 8 keys and an angel chest
• 4 Blood Donation Machines surrounded by lots of Embryos and red hearts
• 4 I - The Magician cards surrounded by rocks
• 2 Gurglings
• A button
• A random item from the treasure room pool behind lots of red poop

Utero

• 19 boils
• 6 boils and 6 brown chests behind key blocks
• 2 Bloodshot Eyes behind spikes
• 3 spike chests behind spikes and retractable spikes
• 8 keys and an angel chest
• 4 Blood Donation Machines surrounded by lots of Embryos and red hearts
• 4 I - The Magician cards surrounded by rocks
• Lokii and a Heart
• A button
• A random item from the treasure room pool behind lots of red poop
• 4 Blood Donation Machines, 3 Flesh Death's Heads, and 2 piles of red poop

Cathedral

• A normal beggar, a bomb bum, a key Master, and a devil beggar
• 9 blue fireplaces
• Uriel
• Gabriel
• 3 piles of rainbow poop
• 5 buttons
• 8 keys and an angel chest
• 7 Psychic Maws
• Urns and spikes
• 5 blue/purple fireplaces

Sheol

• A bomb bum and 2 devil beggars
• A trapdoor
• TNT surrounded by skulls
• 5 spike chests
• Little Horn
• 3 black hearts and 3 Imps
• 3 black hearts behind a troll bomb and 3 mega troll bombs
• 5 buttons behind spikes
• 24 spiders
• 4 buttons and 3 suction pitfalls

The Chest

Not all closets in The Chest are dead-end rooms.

• A room filled with red poop and 2 1+1 free hearts
• A pile of rainbow poop
• 6 buttons
• 8 brown chests and an angel chest
• 8 pills
• 2 Greeds
• 2 Lusts
• 36 coins
• 9 gold bombs
• 6 random pickups

Dark Room

• 3 devil beggars
• 5 red chests
• 3 II - The High Priestess cards
• 4 Begottens
• 3 eternal hearts
• 3 sacks
• 31 dimes
• 3 spike chests
• 4 mega troll bombs and an Imp
• 4 black hearts