Collection Page (Afterbirth)
The table below is a recreation of what each page looks like when Afterbirth is installed and all 436 items have been obtained.
Pages[edit | edit source]
(Click images to open the corresponding item page)
|The Sad Onion|
Increases Tears by 0.7.
|The Inner Eye|
Grants triple shot but decreases tears.
Grants Isaac homing tears.
Increases damage by 0.5, and multiplies it by 1.5x.
Gives Isaac's tears a boomerang effect, and increases range and shot speed.
+1.5 tears, -17.62 range
|Blood of the Martyr|
Increases Damage by 1, and turns Isaac's tears into blood tears.
Follows Isaac around shooting normal tears.
All types of fly except Boom Fly and Red Boom Fly become passive and slowly move towards Isaac. Does not prevent contact damage.
|Halo of Flies|
Spawns two pretty fly familiars that block enemy shots and deal contact damage to enemies.
Increases most stats, enlarges Isaac, grants a heart container and restores all health.
Inflicts poison to enemies who make contact with Isaac. Speed down.
Increases speed by 0.6, range by 5.25, and tear height by 0.5.
Grants Isaac one red heart container and fully restores Isaac's health.
Grants 2 Heart Containers and completely restores health.
Sets your key count to the maximum of 99.
Gives Isaac 99 coins. Can be found multiple times in a single playthrough.
Grants 10 bombs.
Reveals all special rooms (except secret rooms of any kind).
Adds 1 heart container.
Adds 1 heart container.
Grants Isaac one full red heart container.
Grants Isaac one full red heart container.
Adds one heart container.
Increases speed by 0.3.
Increases speed by 0.3.
Increases range and shot height.
|Wire Coat Hanger|
Increases Tears by 0.7.
Upon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.
|The Book of Belial|
Upon use increases damage by 2 for the current room and by a further +50% if the character also has the Blood of the Martyr.
Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it, or increases the chance by 12.5%.
Damages all enemies in the room significantly.
Spawns a pile of poop where the character is standing and knocks nearby monsters back. May yield pickups like regular poop.
Drops a large bomb.
Shoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears.
Upon use, petrifies all enemies in the current room for approximately 4 seconds.
Creates an explosion in the same area as Isaac, dealing half a heart of damage to him and also damaging all enemies caught in the blast radius.
Upon use, inflicts fear to all enemies in the room for 5 seconds.
|Bob's Rotten Head|
Upon use, Isaac holds a poison bomb which can be thrown towards any of the four cardinal points and explodes on impact.
Teleports you to a random room on the level.
Restores 1 whole red heart.
+1 Luck. Increases chance of winning Shell Game Beggar. (Independent of luck stat)
Sets a big red target on the ground (similar to the Epic Fetus item) which can be controlled with tear controls. After 6 seconds or by pressing space again, a huge explosive missile hits it, which damages all enemies caught in its blast radius.
Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them.
|Shoop Da Whoop!|
Fires a laser from Isaac's mouth.
Increases Damage by 1.
Increases damage and increases the chance for a Devil or Angel Room to appear.
Tears are replaced by bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired.
Pulls pickups towards Isaac.
Reveals all rooms for every floor. However, it does not reveal icons or secret rooms.
Allows Isaac to fire tears from the back of his head.
Creates a small yellow pool of creep, which damages enemies that cross it.
A red attack fly circles further out than the Halo of Flies / Pretty Flies, but closer than Forever Alone. Deals more damage than Forever Alone.
|Book of Shadows|
Upon use, creates a protective shield nullifying all types of damage for 10 seconds.
Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections.
|Charm of the Vampire|
Heals the character for half of a red heart for every 13 monsters killed.
Activated Items can be "overcharged" to allow for an additional use.
Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup.
Spawns six troll bombs around the room.
Upon activation, enemies and their projectiles are slowed down for a short duration.
A familiar that follows Isaac around shooting blood tears.
Replaces tears with a piercing laser with unlimited range.
Grants charged tears that deal greater damage when fully charged.
Increases damage by 1 and speed by 0.4.
Increases Speed and Shot Height and decreases Isaac's size, but lowers Range.
Adds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.
|Cube of Meat|
Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
Adds 25 to Isaac's coin count, capping at 99.
Converts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup.
Reveals and opens all Secret Room and Super Secret Room entrances.
|My Little Unicorn|
Upon use, grants invulnerability and increased speed for five seconds, removing the ability to shoot tears and replacing it with the ability to deal contact damage to enemies.
|Book of Revelations|
Adds 1 soul heart, increases the chance for a Devil or Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom).
Increases Damage and Speed, plus adds one Soul Heart.
Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.
Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.
|Lord of the Pit|
Grants flight and increases speed.
Adds one soul heart and allows the breaking of rocks and damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.
|We Need to Go Deeper!|
Creates a trapdoor to go to the next floor. If used in The Womb, it will create a trapdoor to Sheol, even if the player hasn't unlocked it.
|Deck of Cards|
Gives Isaac a random tarot card.
Monstro jumps onto a random enemy, doing area damage. Can damage/kill the player if summoned in an room without enemies.
Gives a random chance for projectiles to fire in all 4 cardinal directions.
A familiar that charges forward and deals touch damage to any enemies in its path.
Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.
|The Small Rock|
Increases damage by 1, increases tears by 0.2, and decreases speed by 0.1.
Reveals type of adjacent rooms, including location for secret rooms and super secret rooms.
Grants one Heart Container and gives 2 Soul Hearts.
Upon use, turns the character into a into a Pac-Man-like creature for 5 seconds, granting invulnerability, inflicting fear on all enemies, and replenishing half a red heart container for every two enemies killed.
|Sack of Pennies|
Isaac is followed by a small bag that drops a coin every 2 rooms.
Follows Isaac around, shooting enemies with an eye laser similar to Technology.
A familiar who will drop a half red heart every 2 rooms.
|The Book of Sin|
Spawns a random pickup, pill, card, or trinket.
Isaac is followed by a small blue cross that will drop a Soul Heart every 4 rooms.
Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed.
Spawns a familiar that follows Isaac around and fires homing tears.
Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
|Mom's Bottle of Pills|
Gives Isaac a random pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.
|The Common Cold|
Adds a chance to shoot poison tears, dealing damage over time when inflicted.
Isaac's tears split in two when they hit something.
Allows Isaac to re-roll collectible items in the current room into other items, depending on the current room's Item Pool.
Gives Isaac 5 bombs, and makes all dropped bombs larger, which have an increased blast radius and increased damage.
|The Pinking Shears|
Separates Isaac's head and body for the current room. Isaac's head, which now has flight, will be under the player's control, while his body will seek out enemies to attack by contact damage.
All sources of damage that would cause more than one half heart of damage are reduced to one half heart instead.
Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.
Isaac releases bad gas, poisoning any enemy in close vicinity.
Spawns an orbital familiar that blocks enemy projectiles, deals contact damage to enemies, and increases the speed of all orbital familiars.
Follows Isaac and automatically fires at enemies in its reach.
Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.
Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.
Reduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges.
Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.
Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
Grants one red heart container, restores 5 red hearts, and increases speed by 0.3.
+1.7 tears, +0.3 speed, reduces damage.
Grants an empty heart container. Increases damage, range and shot height while reducing speed.
|Whore of Babylon|
Increases damage and speed whenever Isaac has half a red heart or less (one red heart for Eve), ignoring any soul or black hearts.
Summons a random familiar for the current room. Can summon familiars not yet unlocked.
|Dead Sea Scrolls|
Triggers the effect of a random activated item from a list of possible options (not every activated item is included).
Gives Isaac 5 Bombs, and causes all dropped bombs to home towards the closest enemy.
Upon use, deals one heart of damage to Isaac and grants +1.2 damage for the current room.
|Forget Me Now|
When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.
Spawns a blue attack fly that orbits a long distance from Isaac.
|Bucket of Lard|
Grants two empty heart containers and heals Isaac by half a heart, but decreases speed by 0.2.
Passively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies.
Isaac is followed by a small bag that drops a Bomb, 1+1 Free, or a Troll Bomb every 3 rooms.
|A Lump of Coal|
The more distance tears travel, the more damage they will do.
Removes one red heart container in exchange for gaining 3 Soul Hearts.
Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups.
Upon activation, Isaac loses a half-heart (one whole heart in The Womb onwards) for a random amount of coins, similar to the blood donation machine.
Deploys a decoy Isaac that eventually explodes with an increased blast radius.
Bombs you place explode only when you use this item. Gives 5 bombs.
Increases damage, and adds 1 heart container.
Allows Isaac to hold 1 additional trinket.
Gives 5 bombs and grants all bombs poison effect.
Spawns several coins around Isaac.
Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.
Increases speed by 0.3 and shot speed by 20%.
A portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickup after collecting a coin. Does not spawn collectibles.
Spawns 2-4 blue flies to damage enemies.
Grants an eternal heart per use.
Isaac holds the axe above his head for as long as the spacebar button is held (or until he leaves the room). While holding the axe, Isaac can break any rock he touches, but cannot attack or pick up other items.
1-3 blue flies randomly spawn every time Isaac gets hit.
Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.
Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears.
Tears have a 1/6 chance of spawning allied blue flies when they hit an enemy.
Grants quadruple shot but decreases tears.
Tears fired from left eye do increased damage.
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to Boom Flies damaging enemies it passes through.
When Isaac is hit, 1 point of an item's charge is filled.
Increases damage as Isaac receives damage. Damage increase stays for the whole floor.
Reveals the map (except the Super Secret Room) and drops a random Tarot Card or soul heart.
|Spirit of the Night|
Grants spectral tears and flight.
|Crack the Sky|
Summons multiple beams of light in random locations around the room, dealing a large amount of damage to any enemy that touches them.
Upon death, the player will respawn as ??? with 3 soul hearts.
Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Spawns a familiar that follows Isaac around and fires spectral tears.
Throws out a blue flame that can pass over gaps (but not through rocks). The flame damages anything in its path.
Increases Shot Speed and damage.
Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern.
Isaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.
Makes Isaac shoot one huge tear. Also reduces Tears to minimum. Damage increased . If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.
Daddy Long Legs' shadow follows Isaac and stomps on enemies.
Damages all enemies in the room and slows them and their projectiles down.
Dagger orbits Isaac, dealing very high damage.
Grants a chance of converting any red hearts pickups into soul hearts instead.
Spawns a familiar that follows Isaac around and fires tears with random effects.
Opens all doors in the current room when activated, including doors which require a key to open and entrances to secret rooms. Opens the big doors in the first room of both The Chest and the Dark Room.
Adds one filled heart container and increases Shot Speed.
Upon activation, 1 coin will be consumed, and a random pickup may drop, similar to the slot machine.
When Isaac receives damage, the bottle breaks and a puddle of blue creep forms, which damages non-flying enemies, similar to Lemon Mishap. The bottle is reformed upon entering a different room.
Grants flight and one eternal heart.
|The Black Bean|
When taking damage, Isaac farts, causing poison damage to all enemies in range.
Passively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack the Sky.
Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
+0.7 tears, +16% shot speed.
Grants flight and one heart container.
Grants spectral tears and flight.
Damages all enemies in the room, but deals a heart of damage to Isaac with each use.
|Guppy's Hair Ball|
Loosely follows behind Isaac. Can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies.
A familiar that mirrors the player's movements and shoots in the opposite direction.
|SMB Super Fan|
Increases all stats.
Adds 99 bombs.
|Telepathy for Dummies|
Upon activation, grants homing tears for the current room.
Adds a heart container and increases damage.
|Magic 8 Ball|
Increases Shot Speed, and drops a tarot card when picked up.
|Mom's Coin Purse|
Spawns 4 random pills around Isaac.
Increases tears by 0.4, and spawns 2 Soul Hearts pickups.
Increases Damage and Range.
Spawns 1 of each (non-collectible) item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.
Spawns 2 keys. Generates additional pickups from chests.
Tears have a chance to charm enemies.
Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.
Enemies that touch you are stunned and turn gold. Any enemy killed while in this state will drop a coin.
Gives one extra pickup (1+1 Free version) of Red Hearts, pennies, bombs, and keys. Does not work with blue, black, and half red hearts, nickels, and dimes.
Has a chance to drop a random pickup when Isaac takes damage.
Using an activated item while it's not charged will charge it and Sharp Plug does 2 full heart damage to Isaac.
Isaac's head is removed from his body and floats around him. Increases Damage by 1 and grants -1 Tear Delay.
|Ball of Bandages|
Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Cube of Meat.
Increases damage, but also increases the chance of champion enemies appearing.
Gives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies.
After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.
When hit, spawns up to 2 blue spiders.
Grants Isaac a permanent 50% chance to respawn with 1/2 of a red heart after death.
Every tear has a small shield which will allow it to block one enemy projectile.
+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room.
A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Adds 3 black hearts and increases Damage by 1.
Adds a chance to spawn blue spiders when firing tears. Restores 1 red heart.
Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Adds one empty heart container. Whenever Isaac takes damage there's a chance that a Red Heart may drop.
+5 Bombs. Upon exploding, bombs shoot 8 tears off in every direction, similar to Tammy's Head. The tears are affected by any tear modifiers Isaac has on his own tears.
Tears bounce off walls, enemies, and environmental objects.
-2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in.
Isaac heals 1 heart instead of taking damage from an explosive source. Adds 5 bombs.
Grants -1 Tear Delay and reduces Range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose Range and Damage scale with Isaac's.
Has a chance of spawning a soul heart or black heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed.
Grants the player one red heart container, one soul heart, and one black heart.
Gives 3 pennies on pick-up. Every time Isaac is damaged, he will drop one additional penny.
Adds a chance to shoot fear tears and decreases tear delay by 1.
Increases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro.
Increases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears.
|Ball of Tar|
Adds a chance to shoot slowing tears and the character leaves a trail of slowing creep behind as he moves, impeding enemies' speed.
Automatically inflicts slow to all enemies in every room.
Upon taking damage, inflicts slow to all enemies for the current room.
Range up and makes shot tears revolve around Isaac until they drop.
Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.
Increases Damage by 1.5, reduces Tears by 0.3 and increases tear size. Grants piercing tears. Tears are replaced by Death's scythes, which is a cosmetic effect only.
Randomly increases and decreases some of the character's stats.
|Contract From Below|
Doubles the number of pickups and chests spawned after clearing a room or performing some other triggering action (such as using a blood donation machine), but reduces the chance for any pickups to spawn at all.
Chance to block projectiles coming from any direction.
Isaac gains a shield that protects him from enemy shots.
Grants a unlimited range piercing laser with random rate of fire that does not replace tears. The laser might occasionally fire with the effect of a random item or trinket, such as Hook Worm, Spoon Bender or Tiny Planet.
Shows secret and super secret room locations on the map.
Increases the size and damage of familiars.
Increases the size of blue spiders and blue flies and doubles the amount of damage they deal.
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
All standard bomb pickups become 1+1 bomb pickups.
Isaac can hold 2 cards at once and all pills are replaced by cards.
Isaac can hold 2 pills at once and all cards are replaced by pills.
Increases luck and HP by 1.
Increases damage by 1 and range by 5 for tears fired from the left eye.
+0.5 tears up, +0.2 shot speed up.
Grants 5 bombs. Isaac's bombs leave behind fire that damages enemies upon contact.
Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.
Randomizes all passive items upon pickup and at the start of each succeeding floor.
Increases Damage by 1 and adds a chance to shoot fear tears.
Prevents curses. Grants one black heart. Increases the chance for a Devil or angel room to appear.
Tears start out massive with high damage, and then shrink down and become weaker over a short range.
After Isaac takes damage, this fly will deal continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared.
Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering The Necronomicon effect.
A familiar that follows behind Isaac. It drips a trail of creep, which slows enemies, and spawns 1-2 blue spiders after each room.
A familiar that spawns blue flies.
Familiar that follows Isaac, leaving blood creep on the ground.
Spawns a friendly familiar leech on the ground that hunts down enemies and heals you for half a heart each time it eats one.
Spawns a familiar that follows Isaac around and has a chance to drop a heart, coin, bomb, or key after clearing a room.
Spawns a familiar that flies around the room in a manner similar to the Boom Fly and explodes on contact with an enemy. Respawns after ten seconds.
Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
When hit, summons a white attack fly similar to Distant Admiration for the current room.
A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
Isaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.
A familiar that damages enemies by chasing them as well as inducing the fear effect.
Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider.
Spawns a large orbital familiar that blocks enemy projectiles and deals slight contact damage to enemies.
Wanders about the room, occasionally spawning blue spiders.
Spawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer.
|How to Jump|
Gives Isaac the ability to jump (over gaps, spikes, etc.).
Rerolls all of Isaac's items.
Has the same effect as the card or rune currently held by Isaac.
|Book of Secrets|
Upon use, gives the effect of Treasure Map, The Compass, or Blue Map for the duration of the current floor.
|Box of Spiders|
Summons 2-4 blue spiders.
Throws a persistent flame that deals high damage and diminishes as it damages enemies or blocks shots.
When at full health, up to 4 extra hearts can be stored in the jar.
Changes all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie.
Upon activation, Isaac gains a black heart.
|Head of Krampus|
Fires a cross-patterned brimstone shot, just like The Fallen and Krampus shoot.
Isaac farts and pushes back nearby enemies.
For 1 coin, damages all enemies in the room.
When used, converts two soul hearts into a heart container.
Upon use, spawns certain pickups or items depending on the floor it is used on. Single-use.
Upon use, grants invulnerability and increased speed for five seconds, but removes the ability to shoot tears.
Speed down; gains speed while in a room with enemies until gaining My Little Unicorn effect for a few seconds.
+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
Adds 3 soul hearts. Grants The Wafer effect for the current room upon taking damage.
Allows you to crush rocks when you walk over them.
Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 10 seconds. Also converts "bad pills" into "good pills".
Gives 6 coins, 6 bombs, and 6 keys and balances out all attributes.
Grants poison tears, which deal damage over time when inflicted.
Increases speed by +0.2 and grants piercing tears.
All stats up.
A trail of blue creep is left behind Isaac, which damages enemies.
-1 Tear Delay, adds knock-back shots and increases tear size.
Doubles damage, halves tears stat, and greatly reduces shot speed.
Adds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts.
Gives one heart container and doubles the healing provided by red hearts.
Automatically negates first taken damage in every room.
Destroys rocks upon contact with Isaac. Adds one heart container and lowers Speed.
Pickups, trinkets, and monsters are magnetically attracted to Isaac's tears.
Grants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.
Tears leave a small, short lasting pool of creep on impact or when their range is depleted.
Suture becomes attached to Isaac, and does touch damage to enemies within its attacking range.
|Cain's Other Eye|
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeper and shoots normal tears in the same direction as Isaac.
|???'s Only Friend|
Summons a big attack fly that can be controlled with the shooting direction-keys.
Pull a chain and ball behind you that will damage enemies on contact and is able to break stones.
Summons a familiar that copies the tears of Isaac's other familiars.
Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.
Teleports Isaac to either the Secret Room, Super Secret Room, Treasure Room, or I AM ERROR.
Upon use, turns Isaac's head into a stationary familiar for the current room which fires normal tears that deal 3.5 damage.
|Breath of Life|
Grants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage.
If the character has half a red heart or no red hearts after taking damage, it triggers the Book of Shadows effect, creating a shield that nullifies all types of damage for 5 seconds. Also allows entrance into The Chest.
If the character has half a red heart or no red hearts after taking damage, it triggers The Necronomicon effect, damaging all enemies in the room. Also allows entrance into the Dark Room.
|The Ludovico Technique|
Instead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy.
Tears shrink and do much less damage, but fire in very rapid succession.
Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
Upon dying, resurrect as Revived Lazarus with one heart container and Anemic item.
Grants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.
Adds 3 heart containers.
Grants two soul hearts. Isaac now repels enemy projectiles.
Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed.
Chance upon entering a room to slow down or speed up every enemy and their attacks. The chance to slow enemies is quite higher than the chance to speed them up.
Throws a short-range boomerang which does a bit of damage and has a high chance to stun the enemy for 2 seconds. Can also be used to grab pickups.
Increases range and shot speed, while adding 1 Black Heart.
Increases speed and reduces character size. Also gives a random pill.
Tears + Shot speed up.
Grants 1 heart container and increases tears, but decreases shot speed.
Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Grants Isaac 1 Black Heart and 3 bombs. Can also give troll bombs.
Increases damage by 1, range by 5.25, and tear height by 0.5.
Grants one full red heart container.
Duplicates all pickups and item pedestals in the room.
When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes.
When used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).
Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.
When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies near Isaac, and send a wave of spikes that deals 10 damage across the room in the direction Isaac is facing.
When used, reduces Isaac's health to half a heart (including soul and black hearts) and fires one large piercing spectral tear that does a lot of damage. The damage done by Glass Cannon scales with Isaac's damage (at base damage it does 45 damage).
+5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects player-spawned troll bombs.
Adds one heart container and drops a random trinket.
+1.25 Range Up. +0.5 Tear Height. +1 Luck Up.
Causes Isaac's activated item to activate twice on each use.
|Box of Friends|
Upon use, duplicates all of Isaac's familiars for the current room.
Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard? pill. Isaac's tears also travel above all obstacles.
|8 Inch Nails|
+1.5 Damage Up. Replaces Isaac's tears with nails, which have increased knockback.
A demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects.
A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage.
Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms.
An orbital angel which does 7 contact damage per tick and blocks enemy shots. Upon blocking 10 shots in a room it drops an eternal heart.
A white orbiting fly which deals 3 contact damage per tick to enemies. This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone.
A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room. If any enemies walk into its path, it will deal 7 contact damage per tick. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle.
Adds 5 bombs. Isaac's bombs explode into 2-4 tiny bombs.
+5 bombs. Bombs stick to enemies and spawn 2-4 blue spiders if they kill an enemy.
Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount.
+2.25 Range Up. +1.5 Tear Height. Isaac's tears travel through walls and appear out of the opposite wall. Isaac's tears also travel over rocks and objects.
Tears and Range up. Spawns 3 random types of hearts on the floor when picked up.
|Curse of the Tower|
Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
A familiar that drops a Little Battery every 4 rooms. Has a small chance to freeze all enemies in the room when hit.
Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot.
Isaac has a random chance to fire a Holy tear, which, when it hits an enemy, will spawn a Crack the Sky-style light beam on the same enemy, dealing damage.
A host familiar that sits on Isaac's head and has a random chance to block enemy shots and retaliate with 3 tears. Grants immunity to explosions.
Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.
Spider enemies no longer target or deal contact damage to Isaac.
Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).
|Pay to Play|
This item turns all doors that require a single key into doors which need a coin to enter instead. This affects shops, item rooms and libraries.
+0.7 tears up. Grants a random item at the start of the next run.
Throwing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be friendly, fighting for Isaac and persisting between rooms.
When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head.
Gives Isaac a Gurdy familiar that will charge around the room dealing contact damage to enemies. Lil Gurdy is charged by holding down a fire button and letting go. The longer the button is held, the faster Lil Gurdy will fling itself across the screen. Lil Gurdy can pass over objects and obstacles in the room.
Spawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.
Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
Spawns a portable key master that follows Isaac and collects keys, giving random chests in return.
A bag that follows Isaac and drops a random rune every 3 rooms.
An angel familiar which follows Isaac and fires homing tears which deal 10 damage at -25% shot speed and a reduced fire rate.
Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.
Zodiac will give Isaac a random zodiac item effect that changes after every floor.
Tears now have a random chance to apply a poison effect, causing 4 or 6 damage per tick to enemies (Similar to The Common Cold item). Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick). Enemies that were poisoned have a chance to drop a black heart when killed.
Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player. This allows for a full 360 degree tear firing radius. Can be overridden by other tear modifiers such as Mom's Knife or Brimstone.
Tears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the size of the ring.
Can be used to place an orange portal and a blue portal. Upon entering a portal, Isaac is teleported to the other portal.
Isaac emits a beam from his face. Isaac's tears travel in the path of the beam.
Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.
|Maw of the Void|
+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.
|Spear of Destiny|
In addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.
Isaac's tears have a chance to stick to enemies and explode.
Chaos causes items to be chosen from random item pools. When picked up, drops between 1-6 random pickups on the floor.
Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.
A familiar that follows Isaac and blocks tears. If a tear hits Farting Baby, there is a high chance for it to fart, which will either knock back, poison, or charm all nearby enemies.
A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
Re-rolls Isaac's speed, range, tears, and damage.
This item will boost one of Isaac's stats depending on the color of the aura around him. The aura will disappear upon taking damage and will reappear with a random color upon entering a new room. A red aura boosts damage, a blue aura boosts rate of fire, a yellow aura boosts speed, and an orange aura boosts range.
Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.
While Isaac has no red hearts, this item grants flight and a random chance to activate an invincibility shield for a few seconds. If Isaac gains any red hearts, these benefits will disappear.
While firing tears, Isaac has a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac. The eye will be destroyed if it comes into contact with an enemy or obstacle.
Each time Isaac kills an enemy, Isaac's damage increases for the current room.
After taking damage a certain amount of times, a permanent demonic familiar spawns.
Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Two items spawn in every Treasure Room. Only one can be taken; the other will disappear.
|Crown of Light|
Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
Allows Isaac to carry two cards or pills (or a combination of both) at the same time.
Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier.
Isaac's tears gain a random effect that changes every shot.
Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it.
Upon use, Isaac farts, charming all nearby enemies.
|Glowing Hour Glass|
When used, this item will rewind time, put Isaac back in the previous room, and undo anything that happened in the current room. Any health, pickups, or items gained or lost will be reset back to the previous state.
|Circle of Protection|
Surrounds Isaac with a large white halo. Once per second, the halo deals Isaac's tear damage to enemies inside it. It may also convert enemy shots entering the halo into friendly purple homing tears.
Greatly increases the chance to find sacks.
A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.
A purple fly familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies.
When used, places an explosive TNT barrel that can be pushed and used to destroy rocks or damage enemies. If used a second time in the same room while the previous TNT barrel is still intact, it will remotely explode the TNT.
Grants four soul hearts and fully restores Isaac's red health.
|Head of the Keeper|
Isaac's tears become coins and now have a chance to drop pennies on the floor upon successfully hitting an enemy.
A blue fly familiar follows Isaac's movements on a 3 second delay. Papa Fly will fire tears at nearby enemies.
Spawns a familiar that will follow Isaac's movements on a 2.5 second delay. Tears that pass through the baby will be doubled and increase in speed.
Gives Isaac 5 bombs, and makes Isaac's bombs have a chance to drop random pickups or charm enemies when they explode.
Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much.
|Jar of Flies|
Every time Isaac kills an enemy, a fly will be added to the jar, up to a maximum of 20. Using the Jar of Flies will release all the flies that are currently in the jar as friendly blue flies that will damage enemies.
A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern.
A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.
Restarts the current room and brings back all enemies, allowing more rewards to be acquired by completing the room.
Tears up, adds 1 soul heart, and decreases Isaac's size.
When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.
Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. In the burst of tears is a kidney stone which deals a lot of damage.
Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active.
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|