Curse Room (Afterbirth+ Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
DLC Indicator.png Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
DLC Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Afterbirth† Indicator.png Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Afterbirth† Indicator.png Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Items in this pool can spawn in the Curse Room. This does not apply to Red Chests.

Activated Collectibles[edit | edit source]

Name ID Icon Quote Description Recharge
Guppy's Head 145 Guppy's Head Icon.png Reusable fly hive Spawns 2-4 blue flies to damage enemies. 1
Guppy's Paw 133 Guppy's Paw Icon.png Soul converter Removes one red heart container in exchange for gaining 3 Soul Hearts. 0
Plan C Afterbirth† Indicator.png 475 Plan C Icon.png Use with caution Kills all enemies in the room, then kills Isaac three seconds later. One time use

Passive Collectibles[edit | edit source]

Name ID Icon Quote Description
Athame DLC Indicator.png 408 Athame Icon.png Call to the void Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.
Black Candle 260 Black Candle Icon.png Curse immunity + evil up Prevents curses. Grants one black heart. Increases the chance for a Devil or Angel Room to appear.
Ceremonial Robes 216 Ceremonial Robes Icon.png Sin up Adds 3 black hearts and increases Damage by 1.
Contract From Below 241 Contract From Below Icon.png Wealth... but at what cost? Doubles the number of pickups and chests spawned after clearing a room or performing some other triggering action (such as using a blood donation machine), but reduces the chance for any pickups to spawn at all.
Curse of the Tower DLC Indicator.png 371 Curse of the Tower Icon.png You feel cursed... Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
Dark Prince's Crown Afterbirth† Indicator.png 442 Dark Prince's Crown Icon.png Loss is power Increases range, tears, and shot speed when at exactly one red heart.
Dead Cat 81 Dead Cat Icon.png 9 lives Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.
Euthanasia Afterbirth† Indicator.png 496 Euthanasia Icon.png Needle shot Adds a chance to fire needles. If a needle kills an enemy, it bursts into more needles.
Gimpy 225 Gimpy Icon.png Sweet Suffering Has a chance of spawning a soul heart or black heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed.
Goat Head 215 Goat Head Icon.png He accepts your offering A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Guppy's Collar 212 Guppy's Collar Icon.png Eternal Life? Grants Isaac a permanent 50% chance to respawn with 1/2 of a red heart after death.
Guppy's Tail 134 Guppy's Tail Icon.png Cursed? Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups.
Little Horn Afterbirth† Indicator.png 503 Little Horn (Item) Icon.png Science! Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
The Mark 79 The Mark Icon.png DMG up Increases Damage and Speed, plus adds one Soul Heart.
Mom's Razor Afterbirth† Indicator.png 508 Mom's Razor Icon.png It's sharp! Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.
The Pact 80 The Pact Icon.png DMG + Tears UP Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.
Pentagram 51 Pentagram Icon.png DMG up Increases damage and increases the chance for a Devil or Angel Room to appear.
Shade Afterbirth† Indicator.png 468 Shade Icon.png It follows Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies.
Tarot Cloth Afterbirth† Indicator.png 451 Tarot Cloth Icon.png I see the future Drops a random card or rune. Doubles the effects of cards and runes.