Curse Room (Afterbirth+ Item Pool)

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Item Pool
Rebirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master
Added in Afterbirth Afterbirth Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Added in Afterbirth Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest
Added in Afterbirth † Afterbirth † Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Bomb Bum
Added in Afterbirth † Greed Mode Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Items in this pool can spawn in the Curse Room. This does not apply to Red Chests.

Activated Collectibles[edit | edit source]

Name ID Icon Quote Description
Guppy's Head 145
Guppy's Head
1 rooms
Reusable fly hive Spawns 2-4 blue flies to damage enemies.
Guppy's Paw 133
Guppy's Paw
Unlimited
Soul converter Removes one red heart container in exchange for gaining 3 Soul Hearts.
Added in Afterbirth † Plan C 475
Plan C
One time use
Use with caution Kills all enemies in the room, then kills Isaac three seconds later.
Added in Afterbirth † Sacrificial Altar 536
Sacrificial Altar
One time use
He demands a sacrifice Upon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.

Passive Collectibles[edit | edit source]

Name ID Icon Quote Description
Added in Afterbirth Athame 408 Athame Call to the void Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.
Black Candle 260 Black Candle Curse immunity + evil up Prevents curses. Grants one black heart. Increases the chance for a Devil or angel room to appear.
Ceremonial Robes 216 Ceremonial Robes Sin up Adds 3 black hearts and increases Damage by 1.
Contract From Below 241 Contract From Below Wealth... but at what cost? Doubles the number of pickups and chests spawned after clearing a room or performing some other triggering action (such as using a blood donation machine), but reduces the chance for any pickups to spawn at all.
Added in Afterbirth Curse of the Tower 371 Curse of the Tower You feel cursed... Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
Added in Afterbirth † Dark Prince's Crown 442 Dark Prince's Crown Loss is power Increases range, tears, and shot speed when at exactly one red heart.
Dead Cat 81 Dead Cat 9 lives Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.
Added in Afterbirth † Euthanasia 496 Euthanasia Needle shot Adds a chance to fire needles. If a needle kills an enemy, it bursts into more needles.
Gimpy 225 Gimpy Sweet Suffering Has a chance of spawning a soul heart or black heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed.
Goat Head 215 Goat Head He accepts your offering A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Guppy's Collar 212 Guppy's Collar Eternal Life? Grants Isaac a permanent 50% chance to respawn with 1/2 of a red heart after death.
Guppy's Tail 134 Guppy's Tail Cursed? Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups.
Added in Afterbirth † Little Horn 503 Little Horn Science! Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
The Mark 79 The Mark DMG up Increases Damage and Speed, plus adds one Soul Heart.
Added in Afterbirth † Mom's Razor 508 Mom's Razor It's sharp! Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.
The Pact 80 The Pact DMG + Tears UP Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.
Pentagram 51 Pentagram DMG up Increases damage and increases the chance for a Devil or Angel Room to appear.
Added in Afterbirth † Shade 468 Shade It follows Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies.
Added in Afterbirth † Tarot Cloth 451 Tarot Cloth I see the future Drops a random card or rune. Doubles the effects of cards and runes.


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