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Curse Room (Greed Mode Item Pool)

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Item Pool
Normal and hard modes only Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Added in Afterbirth  Bomb Bum
Added in Afterbirth Greed mode only
Added in Afterbirth † Greedier mode only
Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Items in this pool can spawn in the Curse Room in Greed mode. This does not apply to red chests.

Activated Collectibles

Name ID Icon Quote Description
Guppy's Head 145
Guppy's Head
1 rooms
Reusable fly hive Spawns 2-4 blue flies to damage enemies.
Guppy's Paw 133
Guppy's Paw
Unlimited
Soul converter Removes one red heart container in exchange for gaining 3 Soul Hearts.

Passive Collectibles

Name ID Icon Quote Description
Cube of Meat 73 Cube of Meat Gotta meat 'em all! Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
Dead Cat 81 Dead Cat 9 lives Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.
Guppy's Collar 212 Guppy's Collar Eternal Life? Grants Isaac a permanent 50% chance to respawn with 1/2 of a red heart after death.
Guppy's Tail 134 Guppy's Tail Cursed? Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups.


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