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|Health||Damage||Tears||Range||Shot Speed||Speed||Luck||Hidden Attributes|
Damage refers to the amount of damage each tear deals to enemies, and is represented by a sword. As damage increases, the size of the tears increases as well. However, tear size is not always a valid indication of how much damage your tears will do. Tears will grow and shrink when your damage changes, but tears of a certain size do not have a specific damage value, and two tears of the same size (in two different runs) are likely to have different damage values.
- Polyphemus is an example of an item which provides a very high Damage stat.
Effective Damage[edit | edit source]
- CharBaseDmg = 3.5 multiplied by a particular Character Modifier,
- TotalDmgUps = the total of all regular damage ups collected (not including special exceptions or damage multipliers),
- FlatDmgUps = the total of all damage ups that are excluded from the above (for example, Curved Horn or Ipecac), and
- EffectiveDmg = the approximate damage that can be expected per tear, or per 'tick' when using Brimstone or Technology 2.
This formula makes most damage upgrades less potent the more that Isaac has. For example, a Pentagram on Isaac would make his total damage (1 * 1.2 + 1)^0.5 = 1.48 * 3.5 = 5.19. Another Pentagram increases this to 6.45 (a 1.26 increase instead of a 1.69 increase). The higher a character's base damage, the more effective Damage Ups will be for that character. Flat damage modifiers and special adjustments like Polyphemus or Sacred Heart happen after the main formula.
Character Modifier[edit | edit source]
The character base damage of each tear is calculated multiplying the base damage of 3.50 with each character's damage modifier. These character modifiers are:
- Eve†: 0.75 • 3.50 = 2.625 per tear
- Isaac, Magdalene, Samson, Lazarus, Eden, Lilith, The Lost, and Apollyon: 1.00 • 3.50 = 3.50 per tear
- ???: 1.05 • 3.50 = 3.675 per tear
- Keeper, Cain and Revived Lazarus: 1.20 • 3.50 = 4.20 per tear
- Judas: 1.35 • 3.50 = 4.725 per tear
- Azazel: 1.50 • 3.50 = 5.25 per beam tick.
- Black Judas: 2 • 3.50 = 7.00 per tear
†: Whore of Babylon has the unique effect of increasing Eve's damage modifier from 0.75 to 1.00 when active. This does not apply to other characters, however.
Damage Multipliers[edit | edit source]
Some items multiply damage rather than simply adding to it. Damage multipliers do not simply multiply the character's damage once; the damage stat is constantly recalculated and the damage multipliers are multiplied with the end result. This means that if a character starts with 3.50 damage and gets a 2x multiplier, their effective damage will be 3.5*2 = 7.00. If an item that grants +1 damage is picked up, the character's effective damage will be 3.5*(1*1.2+1)^0.5*2 = 3.5*(2.2)^0.5*2 = 3.5*1.48*2 = 10.38, and not 7.00 + 1.
Most damage multipliers stack; for example, Proptosis and Eve's Mascara both provide a 2x multiplier, and picking up both will give a total multiplier of 4x. The exception to this is the 1.5x damage multipliers provided by Cricket's Head, Magic Mushroom, and the combination of Blood of the Martyr and The Book of Belial. These multipliers do not stack; for example, picking up both Cricket's Head and Magic Mushroom will result in an overall 1.5x multiplier rather than the expected 2.25x.
Items that affect damage[edit | edit source]
Activated Items[edit | edit source]
|The Book of Belial||34||Temporary DMG up|| Upon use increases damage by 2 for the current room and by a further +50% if the character also has the Blood of the Martyr.
Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it.
Increases the chance for a Devil or Angel Room to appear by 12.5%.
|D8||406||Reroll stats||Re-rolls Isaac's speed, range, tears, and damage.||4|
|The Nail||83||Temporary demon form||Adds one soul heart and allows the breaking of rocks and damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.||6|
|Potato Peeler||487||A pound of flesh||Removes a heart container, increases damage and range, and grants a Cube of Meat.||0|
|Razor Blade||126||Feel my pain||Upon use, deals one heart of damage to Isaac and grants +1.2 damage for the current room.||0|
Passive Items[edit | edit source]
|8 Inch Nails||359||Stick it to 'em!||+1.5 Damage Up. Replaces Isaac's tears with nails, which have increased knockback.|
|Abaddon||230||Evil + DMG up + fear shot||Increases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears.|
|Adrenaline||493||Panic - power||Increases damage based on how many empty heart containers Isaac has.|
|Blood Clot||254||DMG + range up||Increases damage by 1 and range by 5 for tears fired from the left eye.|
|Blood of the Martyr||7||DMG up||Increases Damage by 1, and turns Isaac's tears into blood tears.|
|Bloody Lust||157||RAGE!||Increases damage as Isaac receives damage. Damage increase stays for the whole floor.|
|Bozo||513||Party time!||Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.|
|Capricorn||307||All stats up||All stats up.|
|Cat-O-Nine-Tails||165||Shot speed + damage up||Increases Shot Speed and damage.|
|Ceremonial Robes||216||Sin up||Adds 3 black hearts and increases Damage by 1.|
|Champion Belt||208||DMG + Challenge Up||Increases damage, but also increases the chance of champion enemies appearing.|
|Chemical Peel||154||DMG up||Tears fired from left eye do increased damage.|
|Cricket's Head||4||DMG up||Increases damage by 0.5, and multiplies it by 1.5x.|
|Crown of Light||415||The untainted gain power||Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.|
|Dark Matter||259||Fear shot||Increases Damage by 1 and adds a chance to shoot fear tears.|
|Dead Eye||373||Accuracy brings power!||Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot.|
|Death's Touch||237||Penetrative shot + damage up||Increases Damage by 1.5, reduces Tears by 0.3 and increases tear size. Grants piercing tears. Tears are replaced by Death's scythes, which is a cosmetic effect only.|
|Dog Tooth||445||Bark at the moon!||Increases damage and speed. Upon entering a room adjacent to a secret room, a howl sound effect will play.|
|Eve's Mascara||310||Shot speed down + DMG up||Doubles damage, halves tears stat, and greatly reduces shot speed.|
|Experimental Treatment||240||All stats up, then shuffled||Randomly increases and decreases some of the character's stats. There will always be at least one stat increase and one decrease and the same stats can be increased/decreased multiple times.|
|Godhead||331||God tears||Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.|
|Growth Hormones||70||Speed + DMG up||Increases damage by 1 and speed by 0.4.|
|Guillotine||206||An out-of-body experience||Isaac's head is removed from his body and floats around him. Increases Damage by 1 and grants -1 Tear Delay.|
|The Halo||101||All stats up||Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.|
|Iron Bar||201||Concussive tears||Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.|
|Jesus Juice||197||Damage + range up||Increases Damage and Range.|
|Libra||304||You Feel Balanced||Gives 6 coins, 6 bombs, and 6 keys and balances out all attributes.|
|A Lump of Coal||132||My Xmas Present||The more distance tears travel, the more damage they will do.|
|Lusty Blood||411||Their blood brings rage!||Each time Isaac kills an enemy, Isaac's damage increases for the current room.|
|Magic Mushroom||12||All Stats Up!||Increases all stats and enlargens Isaac.|
|The Mark||79||DMG up||Increases Damage and Speed, plus adds one Soul Heart.|
|Maw of the Void||399||Consume thy enemy!||+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.|
|MEAT!||193||DMG + HP up||Adds a heart container and increases damage.|
|Money = Power||109||$$$ = DMG||Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins.|
|Odd Mushroom||121||DMG up||Grants an empty heart container. Increases damage, range and shot height while reducing speed.|
|Odd Mushroom||120||Fire rate up||Increases Tears and Speed while reducing Damage.|
|The Pact||80||DMG + Tears UP||Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.|
|Pentagram||51||DMG up||Increases damage and increases the chance for a Devil or Angel Room to appear.|
|Polyphemus||169||Mega Tears||Makes Isaac shoot one huge tear. Also reduces Tears to minimum. Damage increased . If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.|
|Proptosis||261||Short range mega tears||Tears start out massive with high damage, and then shrink down and become weaker over a short range.|
|Purity||407||Aura stat boost||This item will boost one of Isaac's stats depending on the color of the aura around him. The aura will disappear upon taking damage and will reappear with a random color upon entering a new room. A red aura boosts damage, a blue aura boosts rate of fire, a yellow aura boosts speed, and an orange aura boosts range.|
|Sacred Heart||182||Homing shots + DMG up||Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.|
|The Small Rock||90||DMG up||Increases damage by 1, increases tears by 0.2, and decreases speed by 0.1.|
|Soy Milk||330||DMG Down + Tears Way Up||Tears shrink and do much less damage, but fire in very rapid succession.|
|Steven||50||DMG up||Increases Damage by 1.|
|Stigmata||138||DMG + HP up||Increases damage, and adds 1 heart container.|
|Sulfuric Acid||463||Acid tears!||Increases damage. Adds a chance to fire acidic tears which can destroy obstacles.|
|Synthoil||345||DMG up + range||Increases damage by 1, range by 5.25, and tear height by 0.5.|
|Technology 2||152||Laser||Decreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously.|
Trinkets[edit | edit source]
|Black Feather||80||With darkness comes power||Increases Isaac's damage for possessing certain evil items.|
|Curved Horn||35||DMG up||Increases damage by 2.|
|Red Patch||40||Your rage grows||Grants a chance of increasing damage by 1.8 for the current room upon taking damage.|
|Samson's Lock||58||Your rage grows||1/15 chance to increase damage by 0.5 for the current room each time an enemy dies.|
Other[edit | edit source]
- In co-op, Rage Baby, Revenge Baby, and Belial Baby will occasionally briefly increase damage. Dark Baby will occasionally briefly increase all stats, including damage. Buddy Baby will occasionally briefly grant the Guillotine effect, which increases damage. Whore Baby will occasionally briefly grant the Whore of Babylon effect, which increases damage.
- The III - The Empress card activates the Whore of Babylon effect for the current room, which increases damage.
- The XI - Strength card activates the Magic Mushroom effect for the current room, which increases damage.
- The XV - The Devil card activates The Book of Belial effect for the current room, which increases damage.
- The Huge Growth card increases damage, range, and Isaac's size for the current room.
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|