The Dank Depths is one of the environments in chapter 3 added in The Binding of Isaac: Afterbirth. The theme of the Dank Depths is tar and sewage. Rocks have a chance to be replaced with spikes.
The Dank Depths' alternate floors are 
The Depths and 
Necropolis.
The Dank Depths are unlocked by defeating It Lives 21 times.
| Monster
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Description
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Clot
|
Randomly wanders around the room, firing 4 tar shots in the ordinal directions.
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Hive
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Walks around the room, avoiding Isaac while spawning Attack Flies. Spawns a large number of flies upon death, which can be Flies, Attack Flies or Pooters.
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Dank Charger
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Slowly moves around the room, charging at Isaac very rapidly when he gets in its line of sight, leaving a trail of slowing Black Creep.
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Dank Globin
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Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, spawns a Spider, and leaves a puddle of slowing Black Creep. Will regenerate after a short time if not killed quickly. Leaves another puddle of Black Creep upon death.
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Leaper
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Hops around the room, dealing touch damage. Occasionally jumps high into the air, dropping down onto Isaac's position while firing 4 blood shots in the cardinal directions.
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Vis
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Randomly wanders around the room. Pauses to charge and fire a Brimstone laser when Isaac gets in its line of sight.
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Double Vis
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Randomly wanders around the room. Pauses to charge and fire a Brimstone laser which fires from both sides when Isaac gets in its line of sight.
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Chubber
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Randomly wanders around the room. Pauses to fire a Charger that deals one heart of damage when Isaac gets in its line of sight. The Charger is invulnerable, blocks Isaac's tears, has limited range, and flies back to the Chubber.
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Knight
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Moves erratically around the room and charges towards Isaac when in line of sight. Can only be damaged from behind.
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Keeper
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Hops around the room, firing 2 blood shots in a V formation at Isaac. Upon damaging Isaac, Isaac drops 2 coins on the ground but loses 3.
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Swarmer
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Slowly floats around the room, spawning several Attack Flies. Spawns Pooters upon taking damage. Spawns a Boom Fly upon death.
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Dank Death's Head
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Moves diagonally around the room, dealing contact damage. Needs to be killed to complete the room.
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Wizoob
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Disappears, then appears near Isaac and spits a cluster of spectral tears at him.
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Dank Squirt
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Dashes towards the player and deals contact damage. Spawns 2 Clots upon death.
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Fat Bat
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Slowly flies towards Isaac. Shoots when Isaac aligns diagonally with it and will actively try to avoid Isaac's shots.
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Black Bony
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Wanders around the room and throws three bones in a row at Isaac when he is in sight. Explodes upon death.
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Black Globin's Body
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Walks aimlessly around the room, occasionally spawning spiders.
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Tar Boy
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Pops out of the ground in random locations and fires a short-ranged spray of shots that leave behind slowing Black Creep. If Isaac stands in the Creep, the Tar Boy can fire shots straight upwards out of the Creep underneath Isaac.
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Gush
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Stationary, harmless enemy that continually creates slowing black creep.
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Mom will always appear in the second floor of this chapter or in the last boss room if Curse of the Labyrinth is active.
- The Dank Depths may resemble some sort of sewers.
- Due to the Dank versions of enemies being more common on this type of floor, it may be the hardest of the other Chapter 3 floors.
- The music in the Dank Depths is titled "Pulso Profundum."
Binding of Isaac: Afterbirth OST
Something Sticky - Beat chapter 3 20 times.
It Lives Unlocks 
Chapters
Achievements
Attributes
Bosses
Cards and Runes
Challenges
Chapters
Characters
Co-op
Items
Item pools
Monsters
Objects
Pickups
Pills
Rooms
Seeds
Transformations
Trinkets
