Name
|
ID
|
Icon
|
Quote
|
Description
|
1 Heart Cost
|
Brother Bobby
|
8
|
|
Friends 'till the end
|
Follows Isaac around shooting normal tears.
|
Ceremonial Robes
|
216
|
|
Sin up
|
Adds 3 Black Hearts and increases damage by 1.
|
Contract From Below
|
241
|
|
Wealth... but at what cost?
|
Doubles the number of pickups and chests spawned after clearing a room or performing some other triggering action (such as using a Blood Donation Machine), but reduces the chance for any pickups to spawn at all.
|
Dark Bum
|
278
|
|
He wants to take your life
|
Spawns a familiar that follows Isaac around and collects Red Hearts. For every one-and-a-half Red Hearts collected, Dark Bum will generate one Soul Heart, one hostile Spider or one friendly Blue Spider.
|
Dark Matter
|
259
|
|
Fear shot
|
Increases damage by 1 and adds a chance to shoot fear tears.
|
Dead Bird
|
117
|
|
Protective buddy
|
Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.
|
Dead Cat
|
81
|
|
9 lives
|
Sets Isaac's Red Heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac respawns with 1 Red Heart in the last safe room.
|
Demon Baby
|
113
|
|
Auto-turret friend
|
Follows Isaac and automatically fires at enemies in its reach.
|
Ghost Baby
|
163
|
|
Spectral buddy
|
Spawns a familiar that follows Isaac around and fires spectral tears.
|
Gimpy
|
225
|
|
Sweet Suffering
|
Has a chance of spawning a Soul Heart or Black Heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed.
|
Goat Head
|
215
|
|
He accepts your offering
|
A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
|
Guppy's Collar
|
212
|
|
Eternal Life?
|
Grants Isaac a permanent 50% chance to respawn with 1/2 of a Red Heart after death.
|
Guppy's Hair Ball
|
187
|
|
Swing it
|
Loosely follows behind Isaac. It can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies.
|
Guppy's Tail
|
134
|
|
Cursed?
|
Increases chance of finding Locked Chests and normal Chests, but reduces chance of finding pickups.
|
Headless Baby
|
269
|
|
Bloody Friend
|
Familiar that follows Isaac, leaving blood creep on the ground.
|
Missing Page 2
|
262
|
|
Evil up. Your enemies will pay!
|
Gives 1 black heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.
|
Pentagram
|
51
|
|
DMG up
|
Increases damage and increases the chance for a Devil or Angel Room to appear.
|
Rotten Baby
|
268
|
|
Infested friend
|
A familiar that spawns blue flies.
|
Sacrificial Dagger
|
172
|
|
My fate protects me
|
A dagger orbits Isaac, dealing very high damage and blocking enemy shots.
|
Sister Maggy
|
67
|
|
Friends 'till the end
|
A familiar that follows Isaac around shooting blood tears.
|
The Mark
|
79
|
|
DMG up
|
Increases Damage and Speed, plus adds one Soul Heart.
|
Whore of Babylon
|
122
|
|
Curse up
|
Increases damage and speed whenever Isaac has half a red heart or less (one red heart for Eve), ignoring any soul or black hearts.
|
Athame
|
408
|
|
Call to the void
|
Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.
|
Betrayal
|
391
|
|
Turn your enemy
|
Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.
|
Black Powder
|
420
|
|
Spin the black circle!
|
Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it.
|
Cambion Conception
|
412
|
|
Feed them hate
|
After taking damage a certain amount of times, a permanent demonic familiar spawns.
|
Empty Vessel
|
409
|
|
I reward an empty vessel
|
While Isaac has no red hearts, this item grants flight and a random chance to activate an invincibility shield for a few seconds. If Isaac gains any Red Hearts, these benefits will disappear.
|
Multidimensional Baby
|
431
|
|
ydduB Buddy
|
Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed.
|
My Shadow
|
433
|
|
Me! And my shaaaadow!
|
Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much.
|
Succubus
|
417
|
|
Damage booster
|
Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier.
|
7 Seals
|
526
|
|
Lil harbingers!
|
Grants a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
|
Death's List
|
530
|
|
Just hope you're not next...
|
Grants a reward if all enemies in a room are killed in the order they are marked.
|
Duality
|
498
|
|
You feel very balanced
|
Whenever a Devil or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered.
|
Lil Delirium
|
519
|
|
Delirious friend
|
Grants a familiar that transforms into another random familiar every 10 seconds.
|
Shade
|
468
|
|
It follows
|
Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers.
|
 2 Hearts Cost
|
Abaddon
|
230
|
|
Evil + DMG up + fear shot
|
Increases damage and speed, removes all Red Heart containers, grants six Black Hearts, and adds a chance to shoot fear tears.
|
Brimstone
|
118
|
|
Blood laser barrage
|
Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
|
Death's Touch
|
237
|
|
Penetrative shot + damage up
|
+1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes.
|
Judas' Shadow
|
311
|
|
Sweet revenge
|
Adds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts.
|
Lil Brimstone
|
275
|
|
Evil Friend
|
A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
|
Lord of the Pit
|
82
|
|
Demon wings
|
Grants flight and increases speed.
|
Mom's Knife
|
114
|
|
Stab stab stab
|
Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.
|
Spirit of the Night
|
159
|
|
Scary
|
Grants spectral tears and flight.
|
The Pact
|
80
|
|
DMG + Tears UP
|
Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.
|
Incubus
|
360
|
|
Dark friend
|
A demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects.
|
Maw of the Void
|
399
|
|
Consume thy enemy!
|
+1.0 Damage. Continuously firing for 2.5 seconds then releasing the fire button creates a black ring around Isaac that rapidly deals damage and can cause enemies to drop Black hearts.
|
Dark Prince's Crown
|
442
|
|
Loss is power
|
Increases range, tears, and shot speed when at exactly one red heart.
|
Eye of Belial
|
462
|
|
Possessed tears!
|
Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
|