E Coli

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Font TeamMeat E.png   Font TeamMeat C.pngFont TeamMeat o.pngFont TeamMeat l.pngFont TeamMeat i.png
Item icon
Item altar

Character appearance
Item Pool Treasure Room.png Treasure Room
Added in AfterbirthGreed mode onlyItem Pool Treasure Room.png Treasure Room
Added in Afterbirth (page 2, column 12, line 6)
Removed in Afterbirth (page 3, column 2, line 4)

E Coli is a passive item.

Effect[edit | edit source]

  • Enemies that touch Isaac are turned into Poop.

Notes[edit | edit source]

  • Poop created by this item is not axis-aligned, and flashes red when hit, similar to damaging Monsters.
  • If you touch the middle section of a Grub with E Coli, it will then split and become two heads (rather than destroying and spawning Maggots).
  • Mullibooms can be turned into poop without taking damage.
  • Added in Afterbirth This item belongs to the Oh Crap set. Collecting all three items from this set will transform Isaac into a walking pile of poop.

Synergies[edit | edit source]

  • Midas' Touch Midas' Touch
    Midas' Touch Icon.pngEnemies that touch you are stunned and turn gold. Any enemy killed while in this state will drop a coin.
    - Enemies touched are turned into Golden Poop.
  • Unicorn Stump Unicorn Stump
    Unicorn Stump Icon.png1 roomsUpon use, grants invulnerability and increased speed for five seconds, but removes the ability to shoot tears.
    - Provides invincibility during which enemies can be touched.
  • Isaac's Heart Isaac's Heart
    Isaac's Heart Icon.pngIsaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.
    - Isaac can turn enemies into poop without taking damage.
  • Petrified Poop Petrified Poop
    Petrified Poop Icon.pngGreatly increases the chances of a pickup dropping when destroying poop.
    - Isaac can get pick up items from poop

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Escherichia coli is a type of intestinal bacteria present naturally in the human intestinal system. However, some harmful strains of E coli can cause food poisoning.
  • This item is used in Challenge #2 (High Brow).

Seeds[edit | edit source]

 PC  DXGN OP4D (treasure room adjacent to spawn)

 PS4  F1WD FBBN (treasure room adjacent to spawn)

 Switch  Greed mode only 8YRM FTHE (First Golden Treasure Room)

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