E Coli

5.100.236

Treasure Room Treasure Room

(page 2, column 12, row 6)(page 3, column 2, row 4)

E Coli is a passive item.

Effect

• Enemies that touch Isaac are turned into Poop.

Notes

• Poop created by this item is not grid-aligned, and flashes red when hit, similar to damaging Monsters.
  • Does not work on bosses.
• If you touch the middle section of a Grub with E Coli, it will then split and become two heads (rather than destroying and spawning Maggots).
• Mullibooms can be turned into poop without taking damage.
• The poops vanish if the room is left and then returned to.
• This item belongs to the Oh CrapWhenever a pile of poop is destroyed, health is replenished by half a heart. set. Collecting three items from this set will transform Isaac into a walking pile of poop.

Interactions

• Hallowed Ground: The generated poops cannot be white.
• MeconiumPoop has a chance to turn into black poop.: The generated poops cannot be black.
• Serpent's Kiss / The Virus: The poops won't drop black hearts, negating the touch effect from these items on non-bosses.

Synergies

• Isaac's Heart: Isaac can turn enemies into poop without taking damage.
• Midas' Touch: Enemies touched are turned into Golden Poop.
• Unicorn Stump: Provides invincibility during which enemies can be touched.

Trivia

• Escherichia coli is a type of intestinal bacteria present naturally in the human intestinal system. However, some harmful strains of E. Coli can cause food poisoning.
• This item is used in Challenge #2 (High Brow).

Seeds

 PC  DXGN OP4D (treasure room adjacent to spawn)

 PS4  F1WD FBBN (treasure room adjacent to spawn)

 Switch  8YRM FTHE (First Golden Treasure Room)

Poop

Items:

• Butt Bombs
• E Coli
• Flush!
• Hallowed Ground
• Midas' Touch
• No. 2
• The Poop
• Skatole

Trinkets:

• Brown CapPoop blocks will explode after being destroyed.
• MeconiumPoop has a chance to turn into black poop.
• Mysterious CandyIsaac farts or poops at random intervals. Getting hit can also trigger the effect.
• Petrified PoopGreatly increases the chances of a pickup dropping when destroying poop.
• Used DiaperGrants the Skatole effect in some rooms.

Cards:

• A Card Against HumanityCovers the entire room with poop. The process is not instant, and the room will not get filled if you leave it before it's done filling.