E Coli

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Font TeamMeat E.png   Font TeamMeat C.pngFont TeamMeat o.pngFont TeamMeat l.pngFont TeamMeat i.png
Item icon
Item altar
Table dividing line 1.png
Character appearance
Table dividing line 2.png
Treasure Room Treasure Room
Greed mode only Treasure Room Treasure Room
Table dividing line 3.png
Added in Afterbirth(page 2, column 12, row 6)
Removed in Afterbirth(page 3, column 2, row 4)

E Coli is a passive item.

Effect[edit | edit source]

  • Enemies that touch Isaac are turned into Poop.

Notes[edit | edit source]

  • Poop created by this item is not grid-aligned, and flashes red when hit, similar to damaging Monsters.
    • Does not work on bosses.
  • If you touch the middle section of a Grub with E Coli, it will then split and become two heads (rather than destroying and spawning Maggots).
  • Mullibooms can be turned into poop without taking damage.
  • The poops vanish if the room is left and then returned to.
  • Added in Afterbirth This item belongs to the Oh CrapOh Crap App.pngWhenever a pile of poop is destroyed, health is replenished by half a heart. set. Collecting three items from this set will transform Isaac into a walking pile of poop.

Interactions[edit | edit source]

  • Added in Afterbirth †Hallowed Ground Hallowed GroundCollectible Hallowed Ground icon.pngSpawns a white poop familiar, which turns into a white poop when Isaac is hurt.: The generated poops cannot be white.
  • Added in Afterbirth †Meconium MeconiumTrinket Meconium icon.pngPoop has a chance to turn into black poop.: The generated poops cannot be black.

Synergies[edit | edit source]

  • Isaac's Heart Isaac's HeartCollectible Isaac's Heart icon.pngIsaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.: Isaac can turn enemies into poop without taking damage.
  • Midas' Touch Midas' TouchCollectible Midas' Touch icon.pngEnemies that touch you are stunned and turn gold. Any enemy killed while in this state will drop a coin.: Enemies touched are turned into Golden Poop.
  • Unicorn Stump Unicorn StumpCollectible Unicorn Stump icon.png1 roomsUpon use, grants invulnerability and increased speed for five seconds, but removes the ability to shoot tears.: Provides invincibility during which enemies can be touched.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Escherichia coli is a type of intestinal bacteria present naturally in the human intestinal system. However, some harmful strains of E coli can cause food poisoning.
  • This item is used in Challenge #2 (High Brow).

Seeds[edit | edit source]

 PC  DXGN OP4D (treasure room adjacent to spawn)

 PS4  F1WD FBBN (treasure room adjacent to spawn)

 Switch  Greed mode only 8YRM FTHE (First Golden Treasure Room)

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