Familiar
Familiars are small companions, usually generated by passive items, that follow and assist the character. Effects of familiars include (but are not limited to) pickup generation, shooting familiars that fire their own tears at enemies, and orbitals that act as projectile shields and/or deal contact damage.
Contents
Temporary Familiars[edit | edit source]
Blue Flies[edit | edit source]
Blue Flies are familiars that will orbit around Isaac and rush towards nearby enemies, dealing damage and dying in the process. Blue flies deal double Isaac's current tear damage. Isaac cannot have more than 64 Blue Flies/Spiders combined.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Guppy's Head | 145 | Reusable fly hive | Spawns 2-4 Blue Flies to damage enemies. | |
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434 | Gotta catch 'em all? | Every time Isaac kills an enemy, a fly will be added to the jar, up to a maximum of 20. Using the Jar of Flies will release all the flies that are currently in the jar as friendly blue flies that will damage enemies. | |
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480 | Gain more friends! | Doubles Isaac's Blue Spiders and Flies, or spawns one if Isaac has none. Turns pickups in the room into Blue Spiders or Flies. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Infestation | 148 | ![]() |
They grow inside | 1-3 Blue Flies randomly spawn every time Isaac gets hit. |
Rotten Baby | 268 | ![]() |
Infested friend | A familiar that spawns blue flies. |
The Mulligan | 151 | ![]() |
They grow inside | Tears have a 1/6 chance of spawning allied blue flies when they hit an enemy. |
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461 | ![]() |
Egg tears! | Adds a chance to fire an egg sack which spawns slowing creep and spawns a blue fly or spider upon hitting an enemy. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Fish Head | 29 | ![]() |
It stinks | Spawns a Blue Fly every time Isaac takes damage. |
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86 | ![]() |
The poop is moving... | Spawns a blue fly from every pile of poop that Isaac destroys. |
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94 | ![]() |
It also stinks! | Items and trinkets that generate Blue Flies or Blue Spiders will generate twice as many. |
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126 | ![]() |
Wealth of flies | Spawns a blue fly every time a coin is picked up. |
Other sources of Blue Flies
- Red Chest: Has a chance to spawn 3 Blue Flies.
- Dark blue champion: Will create 3 Blue Flies when defeated.
- Guppy transformation: Isaac will create Blue Flies whenever his tears or his familiars' tears hit enemies.
- Beelzebub transformation: All enemy flies become Blue Flies.
Berkano: Spawns 3 Blue Flies and 3 Blue Spiders upon use.
Friends Till The End! pill: Spawns three Blue Flies.
As Keeper, all heart pickups turn into Blue Flies.
Black Rune: Turns pickups into Blue Flies and Blue Spiders.
Locusts
[edit | edit source]
Locusts are variants of Blue Flies that are spawned by Locust trinkets and 7 Seals. They behave like regular Blue Flies but have additional special effects. Red Locusts explode on contact with an enemy, dealing an extra 60 damage in the radius. Green Locusts poison the enemy. Yellow Locusts slow the enemy. Black Locusts deal quadruple Isaac's damage instead of double. White Locusts are identical to Blue Flies, but are spawned in high quantities.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
7 Seals | 526 | ![]() |
Lil harbingers! | Grants a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Locust of Conquest | 117 | ![]() |
I bring Conquest | Upon entering a room with enemies, spawns 2-5 White Locusts which damage enemies. |
Locust of Death | 116 | ![]() |
I bring Death | Upon entering a room with enemies, spawns a Black Locust that does a very high amount of damage. |
Locust of Famine | 115 | ![]() |
I bring Famine | Upon entering a room with enemies, spawns a Yellow Locust that damages and slows enemies. |
Locust of Pestilence | 114 | ![]() |
I bring Pestilence | Upon entering a room with enemies, spawns a Green Locust which damages and poisons enemies. |
Locust of War | 113 | ![]() |
I bring War | Upon entering a room with enemies, spawns a Red Locust which detonates upon impact with enemies. |
Blue Spiders[edit | edit source]
Blue Spiders are familiars similar to Blue Flies that crawl erratically and rush towards nearby enemies, dealing damage and dying in the process. Blue Spiders deal 2.5 times Isaac's current tear damage. Unlike Blue Flies, Blue Spiders cannot attack over obstacles such as rocks and pits. Isaac cannot have more than 64 Blue Flies/Spiders combined.

Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Box of Spiders | 288 | It's a box of spiders | Summons 2-4 Blue Spiders. | |
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480 | Gain more friends! | Doubles Isaac's Blue Spiders and Flies, or spawns one if Isaac has none. Turns pickups in the room into Blue Spiders or Flies. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Dark Bum | 278 | ![]() |
He wants to take your life | Spawns a familiar that follows Isaac around and collects Red Hearts. For every one-and-a-half Red Hearts collected, Dark Bum will generate one Soul Heart, one hostile Spider or one friendly Blue Spider. |
Infestation 2 | 234 | ![]() |
Infestation shot | Spawns allied Blue Spiders from killed enemies. |
Juicy Sack | 266 | ![]() |
Sticky babies | A familiar that follows behind Isaac. It drips a trail of creep, which slows enemies, and spawns 1-2 blue spiders after each room. |
Mom's Wig | 217 | ![]() |
You feel itchy... | Adds a chance to spawn blue spiders when firing tears. Restores 1 red heart. |
Sissy Longlegs | 280 | ![]() |
She loves you | Wanders about the room, occasionally spawning Blue Spiders. |
Spider Baby | 211 | ![]() |
Spider revenge | When hit, spawns up to 2 Blue Spiders. |
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403 | ![]() |
Mod buddy! | Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room. |
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367 | ![]() |
Egg sack bombs! | +5 bombs. Bombs stick to enemies and spawn 2-4 Blue Spiders if they kill an enemy. |
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461 | ![]() |
Egg tears! | Adds a chance to fire an egg sack which spawns slowing creep and spawns a blue fly or spider upon hitting an enemy. |
Other sources of Blue Spiders
Berkano: Spawns 3 Blue Flies and 3 Blue Spiders upon use.
- Infested? pill: Spawns Blue Spiders equal to the number of enemies in the room.
- Infested! pill: Spawns a Blue Spider under Isaac and every pile of poop in the room.
Chasing Familiars[edit | edit source]
Familiars in this category actively chase enemies, dealing contact damage to them.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
The Pinking Shears | 107 | Cut and Run | Separates Isaac's head and body for the current room. Isaac's head, which now has flight, will be under the player's control, while his body will seek out enemies to attack by contact damage. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Ball of Bandages | 207 | ![]() |
Gotta lick 'em all! | Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to ![]() |
Cube of Meat | 73 | ![]() |
Gotta meat 'em all! | Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, it makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages. |
Daddy Longlegs | 170 | ![]() |
Daddy's love | Daddy Long Legs' shadow follows Isaac and stomps on enemies. |
Dead Bird | 117 | ![]() |
Protective buddy | Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage. |
Gemini | 318 | ![]() |
Conjoined friend | Suture becomes attached to Isaac, and does touch damage to enemies within its attacking range. |
Leech | 270 | ![]() |
Blood sucker | Spawns a friendly familiar leech on the ground that hunts down enemies. Isaac heals for half a heart whenever Leech kills an enemy. |
Lil Haunt | 277 | ![]() |
Fear him | A familiar that damages enemies by chasing them as well as inducing the fear effect. |
Smart Fly | 264 | ![]() |
Revenge fly | After Isaac takes damage, this fly will do continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared. |
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385 | ![]() |
Bumbo want coin! | Spawns a Beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, doing contact damage. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Eve's Bird Foot | 60 | ![]() |
Revenge from beyond | 5% chance to spawn a ![]() |
Note: Only third and fourth stage Cube of Meat and
Ball of Bandages chase enemies.
Note: Only fourth stage Bumbo chases enemies.
Orbital Familiars[edit | edit source]
Familiars that orbit Isaac, absorbing enemy projectiles and dealing contact damage. Despite their different apparent sizes, most of them have the same effective size with regard of blocking shots or damaging enemies.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Ball of Bandages | 207 | ![]() |
Gotta lick 'em all! | Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to ![]() |
Best Bud | 274 | ![]() |
Sworn protector | When hit, summons a white attack fly similar to ![]() |
Big Fan | 279 | ![]() |
Fat protector | Spawns a large orbital familiar that blocks enemy projectiles and deals slight contact damage to enemies. |
Cube of Meat | 73 | ![]() |
Gotta meat 'em all! | Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, it makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages. |
Distant Admiration | 57 | ![]() |
Attack fly | A red attack fly circles further out than the ![]() ![]() |
Forever Alone | 128 | ![]() |
Attack fly | Spawns a blue attack fly that orbits a long distance from Isaac. |
Guardian Angel | 112 | ![]() |
Extra protection | Spawns an orbital familiar that blocks enemy projectiles, deals contact damage to enemies, and increases the speed of all orbital familiars. |
Guillotine | 206 | ![]() |
An out-of-body experience | Isaac's head is removed from his body and floats around him. Increases Damage by 1 and grants -1 Tear Delay. |
Halo of Flies | 10 | ![]() |
Projectile protection | Spawns two Pretty Flies that block enemy shots and deal contact damage to flies. |
Sacrificial Dagger | 172 | ![]() |
My fate protects me | A dagger orbits Isaac, dealing very high damage and blocking enemy shots. |
Smart Fly | 264 | ![]() |
Revenge fly | After Isaac takes damage, this fly will do continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared. |
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364 | ![]() |
Friendly fly | A white orbiting fly which deals 3 contact damage per tick to enemies. This familiar orbits Isaac at a middle length distance somewhere between ![]() ![]() |
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363 | ![]() |
Protective friend | An orbital angel which does 7 contact damage per tick and attracts and blocks enemy shots. Upon blocking 10 shots in a room it drops an Eternal Heart. |
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509 | ![]() |
Bloody friend | Spawns an orbiting eye familiar that deals contact damage and fires tears every 2 seconds. |
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508 | ![]() |
It's sharp! | Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time. |
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542 | ![]() |
Projectile shield | Spawns a bone familiar that circles around Isaac and reflects enemy shots. |
Pills / Slot Machine[edit | edit source]
Name | Description |
---|---|
Pretty Fly | Grants 1 fly orbital that circles the player, blocking projectiles and damaging fly-type enemies on touch. |
Notes[edit | edit source]
- A maximum of three Pretty Flies can orbit around Isaac.
- It is possible to have more than three orbitals if one has access to co-op mode. If a co-op baby or multiple co-op babies temporarily hold all but two orbitals while Isaac picks up another, and then the co-op baby or co-op babies sign out or die, Isaac will receive their orbitals as well.
Cube of Meat,
Ball of Bandages, and
Sacrificial Dagger take up a Pretty Fly slot.
- For example, If Isaac has three Pretty Flies and picks up a Cube of Meat, the Cube of Meat will replace one of the flies.
- Only first and second stage
Cube of Meat and
Ball of Bandages are orbitals. Therefore, upgrading from level 2 to level 3 will free up a Pretty Fly slot.
- Duplicated orbitals, such as
Forever Alone being copied with the
Box of Friends or
Diplopia, will fly directly opposite the original (having three copies will cause them to fly 120 degrees apart, four will fly at 90 degrees and so on).
Trivia[edit | edit source]
- Pretty Fly is a play on the phrase "pretty fly" as a descriptor.
Pickup Generation Familiars[edit | edit source]
Familiars that generate pickups when certain conditions are met.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Bomb Bag | 131 | ![]() |
Gives bombs | Isaac is followed by a small bag that drops a Bomb, a Double Bomb, a Troll Bomb, or a ![]() |
Bum Friend | 144 | ![]() |
He's greedy | A portable Beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickup after collecting a coin. Does not spawn collectibles. |
Dark Bum | 278 | ![]() |
He wants to take your life | Spawns a familiar that follows Isaac around and collects Red Hearts. For every one-and-a-half Red Hearts collected, Dark Bum will generate one Soul Heart, one hostile Spider or one friendly Blue Spider. |
Little C.H.A.D. | 96 | ![]() |
Gives kisses | A familiar who will drop a half red heart every 3 rooms. |
Mystery Sack | 271 | ![]() |
? | Spawns a familiar that drops a heart, coin, bomb, or key every 5-6 rooms. |
Sack of Pennies | 94 | ![]() |
Gives money | Isaac is followed by a small bag that drops a coin every 2 rooms. |
The Relic | 98 | ![]() |
Soul generator | Isaac is followed by a small blue cross that will drop a Soul Heart every 5-6 rooms. |
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385 | ![]() |
Bumbo want coin! | Spawns a Beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, doing contact damage. |
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372 | ![]() |
Bbbzzzzzt! | A battery familiar that occasionally drops a Lil' Battery, gives an active item charge, or freezes all enemies in the room. |
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388 | ![]() |
He wants your keys! | Spawns a portable key master that follows Isaac and collects keys, giving random chests in return. |
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362 | ![]() |
What's in the box? | Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms. |
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389 | ![]() |
Rune generator | A bag that follows Isaac and drops a random rune every 5-6 rooms. |
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491 | ![]() |
Pills pills pills! | Spawns a familiar that drops random pills every 3 rooms cleared. Upon using a pill, all enemies in the room are poisoned. |
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500 | ![]() |
Gives sacks | Spawns a sack familiar that drops a sack every 5-6 rooms cleared. |
Spawning Familiars[edit | edit source]
Familiars that spawn friendly Blue Spiders or Blue Flies.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Dark Bum | 278 | ![]() |
He wants to take your life | Spawns a familiar that follows Isaac around and collects Red Hearts. For every one-and-a-half Red Hearts collected, Dark Bum will generate one Soul Heart, one hostile Spider or one friendly Blue Spider. |
Juicy Sack | 266 | ![]() |
Sticky babies | A familiar that follows behind Isaac. It drips a trail of creep, which slows enemies, and spawns 1-2 blue spiders after each room. |
Rotten Baby | 268 | ![]() |
Infested friend | A familiar that spawns blue flies. |
Sissy Longlegs | 280 | ![]() |
She loves you | Wanders about the room, occasionally spawning Blue Spiders. |
Shooting Familiars[edit | edit source]
Familiars that attack with their own tears as long as Isaac is attacking or charging a shot.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Scissors | 325 | Lose your head | Upon use, turns Isaac's head into a stationary familiar for the current room which fires normal tears that deal 3.5 damage. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Abel | 188 | ![]() |
Mirrored buddy | A familiar that mirrors the player's movements and shoots in the opposite direction. |
Ball of Bandages | 207 | ![]() |
Gotta lick 'em all! | Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to ![]() |
Brother Bobby | 8 | ![]() |
Friends 'till the end | Follows Isaac around shooting normal tears. |
Cain's Other Eye | 319 | ![]() |
Near-sighted friend | Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeper and shoots normal tears in the same direction as Isaac. |
Cube of Meat | 73 | ![]() |
Gotta meat 'em all! | Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, it makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages. |
Demon Baby | 113 | ![]() |
Auto-turret friend | Follows Isaac and automatically fires at enemies in its reach. |
Ghost Baby | 163 | ![]() |
Spectral buddy | Spawns a familiar that follows Isaac around and fires spectral tears. |
Harlequin Baby | 167 | ![]() |
Double shot buddy | Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern. |
Lil Brimstone | 275 | ![]() |
Evil Friend | A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting. |
Little Gish | 99 | ![]() |
Sticky friend | Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed. |
Little Steven | 100 | ![]() |
Psychic friend | Spawns a familiar that follows Isaac around and fires homing tears. |
Mongo Baby | 322 | ![]() |
Mongo Friend | Summons a familiar that copies the tears of Isaac's other familiars. |
Rainbow Baby | 174 | ![]() |
Random buddy | Spawns a familiar that follows Isaac around and fires tears with random effects. |
Robo-Baby | 95 | ![]() |
Friends 'till the bbbbzzzt | Follows Isaac around, shooting enemies with an eye laser similar to Technology. |
Robo-Baby 2.0 | 267 | ![]() |
We worked out all the kinks | Fires lasers at any enemy in its line of sight and moves based on the direction Isaac is firing tears. |
Sister Maggy | 67 | ![]() |
Friends 'till the end | A familiar that follows Isaac around shooting blood tears. |
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361 | ![]() |
Your fate beside you | A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage. |
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360 | ![]() |
Dark friend | A demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects. |
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435 | ![]() |
4-way buddy! | A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern. |
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390 | ![]() |
Sworn friend | An angel familiar which follows Isaac and fires homing tears which deal 10 damage and have -25% shot speed. |
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518 | ![]() |
What could it be?! | Grants a familiar with a random tear effect. The familiar is randomized at the start of each floor. |
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471 | ![]() |
Ain't he cute? | Spawns a familiar that fires clusters of tears. Must be charged before shooting. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
???'s Soul | 57 | ![]() |
Imaginary Friend | Spawns a familiar that floats slowly around the room on a pattern similar to The Peeper and fires spectral and homing tears. |
Isaac's Head | 54 | ![]() |
Dead friend | Gives the player Isaac's severed head as a tear-firing familiar. Fires piercing tears. |
Umbilical Cord | 33 | ![]() |
Fetal Protection | When Isaac's health is brought to half a red heart and no soul hearts, a Little Steven familiar spawns for the current room. |
Note: Only second stage Cube of Meat and
Ball of Bandages shoot tears.
Note: Demon Baby shoots tears even when Isaac is not attacking.
Others[edit | edit source]
Familiars that don't fit into any of the above categories or that produce multiple effects.
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
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504 | Friendly fly | Spawns a stationary fly familiar that fires tears at nearby enemies. | |
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516 | Sprinkles. | Upon use, spawns a sprinkler that rotates and fires tears. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
1up! | 11 | ![]() |
Extra life | Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health and lose the 1up!. |
BBF | 272 | ![]() |
Big Beautiful Fly | Spawns a familiar that flies around the room like the Boom Fly and explodes on contact with an enemy. Respawns after ten seconds. |
Bob's Brain | 273 | ![]() |
Explosive thoughts | Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds. |
Dead Cat | 81 | ![]() |
9 lives | Sets Isaac's Red Heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac respawns with 1 Red Heart in the last safe room. |
Dry Baby | 265 | ![]() |
Immortal Friend | Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering ![]() |
Guppy's Hair Ball | 187 | ![]() |
Swing it | Loosely follows behind Isaac. It can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies. |
Headless Baby | 269 | ![]() |
Bloody Friend | Familiar that follows Isaac, leaving blood creep on the ground. |
Holy Water | 178 | ![]() |
Splash! | Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep. The bottle is reformed upon entering a different room. |
Isaac's Heart | 276 | ![]() |
Protect It | Isaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt. |
Key Piece 1 | 238 | ![]() |
??? | Combined with Key Piece 2, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan. |
Key Piece 2 | 239 | ![]() |
??? | Combined with Key Piece 1, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan. |
Little Chubby | 88 | ![]() |
Attack Buddy | A charger familiar that charges forward and deals touch damage to any enemies in its path. |
Punching Bag | 281 | ![]() |
Scape Goat | Spawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer. |
Samson's Chains | 321 | ![]() |
The ol' ball and chain | Spawns a ball and chain familiar Isaac pulls behind him that damages enemies, blocks shots, and destroys rocks. |
The Peeper | 155 | ![]() |
Plop! | Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to Boom Flies damaging enemies it passes through. |
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387 | ![]() |
Peace be with you | Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it. |
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404 | ![]() |
It farts! | A familiar that follows Isaac and blocks tears. If a tear hits Farting Baby, there is a high chance for it to fart, which will either knockback, poison, or charm all nearby enemies. |
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405 | ![]() |
Game breaking bug, right away! | A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over. |
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384 | ![]() |
A gurd of your own! | Gives Isaac a Gurdy familiar that will charge around the room dealing contact damage to enemies. Lil Gurdy is charged by holding down a fire button and letting go. The longer the button is held, the faster Lil Gurdy will fling itself across the screen. Lil Gurdy can pass over objects and obstacles in the room. |
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365 | ![]() |
Lost protector | A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact within each room. If any enemies walk into its path, it will do 7 contact damage per tick. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously traveling until it meets another wall or obstacle. |
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436 | ![]() |
Don't cry over it... | A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room. |
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431 | ![]() |
ydduB Buddy | Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed. |
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426 | ![]() |
Follows my every move... | A purple fly familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies. |
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430 | ![]() |
Turret follower | A blue fly familiar follows Isaac's movements on a 3 second delay. Papa Fly will fire tears at nearby enemies. |
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403 | ![]() |
Mod buddy! | Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room. |
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417 | ![]() |
Damage booster | Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier. |
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526 | ![]() |
Lil harbingers! | Grants a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts. |
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528 | ![]() |
Eclipsed by the moon | Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears. |
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511 | ![]() |
He's violent | Spawns a fly familiar that orbits around a random enemy and deals 5 damage per tick to enemies it comes in contact with. |
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473 | ![]() |
Chub chub | Spawns a fat charger familiar that slowly charges forward, blocking shots and damaging enemies in its path. |
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469 | ![]() |
:( | Spawns a cloud familiar that leaves a trail of tears that damages enemies. Has a chance to spawn damaging beams of light onto enemies that touch the cloud. |
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467 | ![]() |
Watch where you point that! | Spawns a finger familiar that points at enemies, dealing constant damage. |
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543 | ![]() |
Portable sanctuary | Spawns a white poop familiar, which turns into a white poop when Isaac is hurt. White poop has an aura that halves tear delay and can block enemy shots. |
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470 | ![]() |
Lil hush! | Spawns a Hush familiar that bounces around the room and deals contact damage. While firing tears, it stops moving. |
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548 | ![]() |
Fetch! | Spawns a familiar that flies the room while firing, dealing a flat 7 damage to enemies that come in contact and retrieving pickups. |
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472 | ![]() |
Lord of the dead! | Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, it stops moving. |
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519 | ![]() |
Delirious friend | Grants a familiar that transforms into another random familiar every 10 seconds. |
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537 | ![]() |
Puking buddy | Spawns a random pill, and grants a small Spewer familiar that charges up and fires creep. Using pills changes the creep type. |
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539 | ![]() |
Sacrificial insemination | Spawns an egg familiar, which cracks and turns into a random friendly enemy when Isaac is hurt. The egg regenerates upon entering a different room. |
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544 | ![]() |
Stabbing time | Spawns a bone familiar that can be aimed with the fire buttons and does contact damage. |
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468 | ![]() |
It follows | Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers. |
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492 | ![]() |
Yo listen! | +1 luck. Spawns a fairy familiar that points out secret room entrances and tinted rocks. |
Name | ID | Icon | Quote | Description |
---|---|---|---|---|
Mom's Toenail | 16 | ![]() |
??? | Once a minute, Mom's foot randomly stomps down somewhere in the room. |
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97 | ![]() |
Sick... | When hit, there is a small chance a removed tonsil familiar starts following Isaac, blocking enemy shots. |
Unlockable Achievements[edit | edit source]
Buddy in a Box - Pick up 5 familiars in a single run.
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