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When He broke the third seal, I heard the third living creature saying, “Come.” I looked, and behold, a black horse; and he who sat on it had a pair of scales in his hand. And I heard something like a voice in the center of the four living creatures saying, “A quart of wheat for a denarius, and three quarts of barley for a denarius; and do not damage the oil and the wine.”
~ Revelations 6:5-6
Boss Famine.png
Base HP
Stage HP
Found In
Stage basement.png Stage cellar.png Stage burning basement.png Super Secret Room Icon.png
(Later Floors)
Dropped Items
Ball of BandagesBall of Bandages
Cube of MeatCube of Meat

Unlocked By
The Harbingers Defeat Mom for the 1st time

Famine is a boss that can appear in The Basement, The Cellar, or the Burning Basement. He is one of the four Harbingers, and the horseman of Chapter 1.

Behavior[edit | edit source]

Phase 1

  • If Isaac is to the left or right of Famine, it will commence charging across the screen.
  • Spawns up to two Pooters to assist it during the fight, and will not spawn any more until one of the two Pooters are killed.

Phase 2

  • When Famine takes a sufficient amount of damage, its body and horse will explode and vanish while only its head remains. Famine's head behaves similarly to a Maw, slowly moving towards Isaac. If in line with Isaac, it will briefly stop and fire a triple shot.

Champion versions[edit | edit source]

  • Blue: This version charges more often and it will slightly home in on Isaac, (similar to the Dark One's charge attack). It cannot summon Pooters and will instead regularly shoot six tears radially. In Phase 2 it will vomit out a large amount of blood, similar to Monstro's attack, with a lower rate of fire than the non-champion version. His head will leave a trail of damaging red creep. Will always drop a Soul Heart upon death.

Unlockable achievements[edit | edit source]

Gallery[edit | edit source]

Bugs[edit | edit source]

Bug Bug! If phase 2 of Famine is inflicted with fear or confusion, instead of running away from Isaac, it will chase him without attacking.
Bug Bug! If Famine is stunned at the same time as he tries to shoot Isaac, after the effect wears off, his shots will be fired without his corresponding animation.

Trivia[edit | edit source]

  • Famine is one of the Four Horsemen of the Apocalypse mentioned in the Bible. However, in the Bible, Famine is depicted as riding a black horse rather than the tan horse seen in-game.
  • Famine appeared in the original Binding of Isaac.
  • A famine is the scarcity of food over a large area, which can explain Famine's emaciated appearance.
  • Famine is shown with pupils in his Rebirth artwork, which is absent in his original artwork.

Bosses Boss Monstro.png
Chapter 1 Blighted OvumDingleThe Duke of FliesFamineFistulaGeminiGurdy Jr.GurglingsThe HauntLarry Jr.MonstroPinStevenWidow
Added in Afterbirth DangleLittle HornRag ManTurdlings
Chapter 2 C.H.A.D.ChubDark OneGurdyGurdy Jr.The HollowThe HuskMega FattyMega MawPeepPestilencePolycephalusCarrion QueenThe Wretched
Added in Afterbirth The ForsakenThe FrailThe Stain
Added in Afterbirth † Big HornRag Mega
Chapter 3 The AdversaryThe BloatThe CageCarrion QueenThe GateGishLokiMask of InfamyMonstro IIWarThe WretchedMom
Added in Afterbirth Brownie
Added in Afterbirth † Sisters Vis
Chapter 4 BlastocystThe BloatConquestDaddy Long LegsDeathIt LivesLokiiMama GurdyMom's HeartMr. FredScolexTeratomaTriachnid
Added in Afterbirth Blue Womb Added in Afterbirth Hush
Chapter 5 The FallenIsaacSatan
Chapter 6 ???The LambMega Satan
Added in Afterbirth Greed Mode Added in Afterbirth Ultra Greed
Added in Afterbirth † Ultra Greedier
Added in Afterbirth † The Void Added in Afterbirth † Delirium
Chapters 1-4 The FallenThe Headless Horseman

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