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Extinguishes all Normal and Red Fire Places in the room.
Turns lava-filled pits in the Mines into solid rock, allowing them to be walked over.
This item belongs to the Oh Crap set. Collecting three items from this set will transform Isaac into a walking pile of poop.
Notes
Poops produced by this item act similarly to regular enemies, which causes them to flash red when hit. Certain items will also behave like the poop was a normal enemy, such as BBF.
Enemies that are turned into poop act more similarly to regular poop by crumbling upon being attacked.
Enemies that are turned into poop do not count towards on kill effects such as health regeneration from Charm of the Vampire or the damage increase from Lusty Blood.
Using it against the Champion version of a monster will forfeit the chance to get the champion's drop.
When used inside a crawl space the ladders will be covered in water but the walls will not.
Synergies
120 Volt / Jacob's Ladder: Since Flush! floods the room with water, it is now considered a wet environment, which significantly increases the arcing distance of the electricity created by these items.
Blood Puppy: Instantly tames a hostile Blood Puppy and leaves behind a poop.
Book of Virtues: Spawns brown wisps in the middle ring. An additional wisp is spawned for each enemy turned into Poop.
Death's List: Enemies that die by being turned into poop do not disrupt the Death's List chain and clearing a room by turning all its enemies into poop still grants Isaac the Death's List reward.
Dirty Mind: Enemies that are turned into poop generate double the normal amount of Dips.
Oh Crap: Destroying poops created from enemies do not heal Isaac.
In-game Footage
Gallery
3DS The icon of Flush! as seen on the lower 3DS screen.
Trivia
A rare 2x1 tall room behaving like a closet exists in Mines with Flush! as a guaranteed item. If Isaac has already found Flush!, the item in the closet does not change.