Gapers are monsters that resemble Isaac but have blood instead of tears, and their skin is paler. Gapers are commonly found in The Basement and Cellar.
Gapers will walk towards Isaac by the most direct route possible. If there is no way to reach Isaac, due to obstacles such as rocks or poop blocking the way, they will stand still until a proper route is created.
Sometimes they turn into Pacers or Gushers after dying.
Variations
Frowning Gaper
Frowning Gapers look identical to regular Gapers but have empty eye sockets that appear closed before they get close to Isaac. When awake, they have the same head sprite as Horfs. Frowning Gapers move quicker than Gapers and spawn Pacers and Gushers more often.
Flaming Gaper
Flaming Gapers behave identically to regular Gapers. They appear to be on fire but despite this, they aren't affected by it in any way. They mainly replace most of the regular Gapers in the Burning Basement.
Cyclopia
The Cyclopia moves slower than normal Gapers, but leaves behind a trail of creep and occasionally fires a blood shot towards Isaac.
Gurgle
Gurgles are enemies that look identical to Frowning Gapers and are very common in Error: The given stage ("The Catacombs") does not exist.. They are green and have at least quadruple the health of a normal Gaper. When they get near Isaac, they fire an 
Ipecac shot at him. Killing it has a small chance for it to become a Splasher.
They fire Ipecac shots at Isaac at a very short range. These shots will kill other enemies in their Area of Effect, but Gurgles themselves are immune to their own shots. Like other enemies' explosive projectiles, Gurgles' shots can be used to shatter Rocks or open secret rooms by making Gurgles fire at the appropriate area.
Gurgles are somewhat more predictable and accurate in their shots compared to guts and walking guts, because they will always shoot at Isaac's position. However, the timing of their shots is unpredictable. As such, an effective strategy of delivering explosives to a particular area (e.g. tinted rock or potential secret room entrance) is to stand still in that position as long as possible before moving to avoid getting touched, to prompt the Gurgles to shoot their projectiles at you.
Skinny
A Skinny is a variant of the Gaper with melted faces and a very small creep trail behind them. Skinnies travel much slower than normal Gapers, making them easy to kill without receiving damage.
Rotty
Rotties are paler versions of Skinnies that can turn into Bonys or several Attack Flies after being killed.
Crispy
Crispies are a Skinny variant added in Booster Pack #5. They initially start slow but will turn darker in color until it becomes crispy black and begin to chase the player at a much faster pace as they take damage. They also take damage regardless of Isaac every few moments.
Null
Nulls appear fairly rarely in the Depths and below. They behave similarly to Frowning Gapers, but walk faster and have the ability to phase in and out of visibility.
Notes
- In Chapter 3, Nulls are most commonly encountered in a 2x2 room layout, where six of them are encased in the center, unable to chase Isaac. Isaac has to blast away some skulls first to open the path to them. Flight, as well as spectral tears, do very well here, as the player can fly in, drop a bomb, and leave, and the enemies will remain stationary where they were last chasing the player.
- White Champion Nulls may not be able to turn invisible while invincible.
Blue Gaper
Blue Gapers behave similarly to regular Gapers and are spawned during the Hush boss fight. They can rarely appear in Bedrooms and I AM ERROR rooms.
They can rarely appear in a closet in The Basement,[1] The Depths, and Necropolis.
Greed Gaper
Greed Gapers behave similarly to regular Gapers and are spawned during the Ultra Greed boss fight.
2-4 Greed Gapers have a chance to appear in Treasure Rooms, and 2 Greed Gapers may rarely replace the shopkeeper in Shops.
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Trivia
- When the
Head of the Keeper is picked up as Keeper, he will look similar to the Greed Gaper. - The appearance of Cyclopias is reminiscent of the fatal birth defect of the same name, which is characterized by the failure of the embryonic prosencephalon to properly divide the orbit of the eyes into two cavities.
- Unlike Skinnies, Rotties make Gaper noises when chasing the player.
- A Stoney makes the same sound as a Large champion Gaper.
- Frowning Gapers and Nulls don't make noises until they open their eyes and start chasing the player quicker.
- Crispies were first revealed on Twitter by Tyrone Rodriguez.[2]
- Greed Gapers are also known as Greedlings, a name given by a card of it from The Binding Of Isaac: Four Souls, although it's seldom referred to as a "Greedling" by players.
Gallery
- Frowning Gaper 1.png
Frowning Gaper Before It Moves Close To Isaac
- Null 1.png
Null Before It Moves Close To Isaac
Original Semi-Concept Art For Crispies, By LeatherIceCream
Bugs
 Bug!
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If a Dark-Red champion Frowning Gaper does not become a gusher or pacer and reforms, the head won't appear until the Gaper sees the player. The same goes for a normal Gaper, however, the head won't appear once reformed. |
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| Bug!
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If an Explosivo tear is stuck to a Null when it becomes invisible, the tear will fall to the ground. |
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| Bug!
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 If a Champion Gaper is killed and it turns into a Pacer/Gusher, it will no longer be a champion.
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References
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 The Binding of Isaac: Rebirth
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