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Font TeamMeat G.pngFont TeamMeat l.pngFont TeamMeat a.pngFont TeamMeat u.pngFont TeamMeat c.pngFont TeamMeat o.pngFont TeamMeat m.pngFont TeamMeat a.png
Item icon
Item altar
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Character appearance
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Treasure Room Treasure Room
Greed mode only Treasure Room Treasure Room
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(page 4, column 15, row 5)
Added in Afterbirth †

Glaucoma is a passive item added in Afterbirth †.

Effects[edit | edit source]

  • Adds a chance to shoot concussive tears, causing enemies to walk around randomly.
    • The confusion caused by Glaucoma tears is effectively permanent for normal enemies, and very long duration compared to most status effects for bosses.
  • Makes the screen darker.

Notes[edit | edit source]

  • Not affected by Luck.

Synergies[edit | edit source]

  • Black Candle Black CandleCollectible Black Candle icon.pngPrevents curses. Grants one black heart. Increases the chance for a Devil or angel room to appear. : Removes the darker screen caused by Glaucoma.
  • Night Light Night LightCollectible Night Light icon.pngA cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.: Removes the darker screen caused by Glaucoma.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss.

Seeds[edit | edit source]

 Switch  Greedier mode only LG8R 219Y (First Golden Treasure Room)

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