Glyph of Balance

Angel Room Angel Room   (page 4, column 19, line 5)   Defeat Ultra Greedier as MagdaleneGlyph of Balance

Glyph of Balance is an unlockable passive item added in Afterbirth †.

Effects

• Grants 2 soul hearts.
• Modifies drops from champion enemies depending on certain conditions. The priorities of the drops, in order, are as follows:
  • Soul Hearts: When Isaac has no red heart containers and less than 2 soul hearts.
  • Full Red Hearts: While at 0.5 red hearts.
  • Keys: When Isaac has no keys. 
  • Bombs: When Isaac has no Bombs.
  • Full Red Hearts: When Isaac has at least half a red heart container empty.
  • Coins: While Isaac has less than 15 pennies.
  • Keys: When Isaac has less than 5 keys. 
  • Bombs: When Isaac has less than 5 bombs.
  • Trinkets: If Isaac has no trinkets and there are no trinkets on the ground in the room.
  • Soul Hearts: When Isaac has less than 6 total heart containers of any kind.
  • If none of the above conditions are true, champions will resume dropping their regular pickups.

Notes

• Because of how the item works in the priorities listed above, this item is detrimental for The Lost as he is always considered to be at half a soul heart, and all champion drops are replaced with soul hearts which are useless to him.
• This item sees more use in Hard mode.

Synergies

• Champion BeltIncreases damage, but also increases the chance of champion enemies appearing.: Increases frequency of champion spawns and Isaac's damage.
• Purple HeartIncreases chance for challenge rooms to be boss challenge rooms / Causes more enemy champions to spawn.: Increases frequency of champion spawns.
• Equality!Turns pickups into their doubled versions while Isaac's numbers of coins, bombs, and keys are equal.: Makes it easier to trigger Equality!'s effects.