Golden Chest (Greed Mode Item Pool)

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Item Pool
Normal and hard modes only Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Added in  Afterbirth  Bomb Bum
Added in  Afterbirth Greed mode only
Added in Afterbirth † Greedier mode only
Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Activated Collectibles

Name ID Icon Quote Description
Bob's Rotten Head 42
Bob's Rotten Head
3 rooms
Reusable ranged bomb Upon use, Isaac holds a poison bomb which can be thrown towards any of the four cardinal points and explodes on impact.
Guppy's Head 145
Guppy's Head
1 rooms
Reusable fly hive Spawns 2-4 blue flies to damage enemies.
Tammy's Head 38
Tammy's Head
1 rooms
Reusable tear burst Shoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears.

Passive Collectibles

Name ID Icon Quote Description
Abel 188 Abel Mirrored buddy A familiar that mirrors the player's movements and shoots in the opposite direction.
Bob's Brain 273 Bob's Brain Explosive thoughts Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
Cricket's Head 4 Cricket's Head DMG up Increases damage by 0.5, and multiplies it by 1.5x.
Fate's Reward 361 Fate's Reward Your fate beside you A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage.
Fate 179 Fate Flight eternal Grants flight and one eternal heart.
Infamy 242 Infamy Damage Reduction Chance to block projectiles coming from any direction.
Steven 50 Steven DMG up Increases Damage by 1.


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