Golden Chest (Item Pool)

Item Pool

Treasure Room

Shop

Library

Curse Room

Boss

Secret Room

Devil Room

Angel Room

Golden Chest

Red Chest

Beggar

Devil Beggar

Key Master

Bomb Bum

Treasure Room

Shop

Library

Curse Room

Boss

Secret Room

Devil Room

Angel Room

Golden Chest

Items in this pool can appear in Locked Chests, Bomb Chests, and Vaults.

Activated Collectibles

Name	ID	Icon	Quote	Description
Bob's Rotten Head	5.100.42		Reusable ranged bomb	Upon use, Isaac holds a poison bomb which can be thrown towards any of the four cardinal points and explodes on impact.
Guppy's Head	5.100.145		Reusable fly hive	Spawns 2-4 Blue Flies to damage enemies.
Tammy's Head	5.100.38		Reusable tear burst	Shoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears.
IV Bag	5.100.135		Portable blood bank	Upon activation, Isaac loses a half-heart (one whole heart in The Womb onwards) for a random amount of coins, similar to the Blood Donation Machine.

Passive Collectibles

Name	ID	Icon	Quote	Description
Abel	5.100.188		Mirrored buddy	A familiar that mirrors the player's movements and shoots in the opposite direction.
Bob's Brain	5.100.273		Explosive thoughts	Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
Cricket's Head	5.100.4		DMG up	Increases damage by 0.5, and multiplies it by 1.5x.
Fate	5.100.179		Flight eternal	Grants flight and one Eternal Heart.
Goat Head	5.100.215		He accepts your offering	A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Infamy	5.100.242		Damage Reduction	Chance to block projectiles coming from any direction.
Fate's Reward	5.100.361		Your fate beside you	A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage.
Head of the Keeper	5.100.429		Penny tears!	Isaac's tears become coins and now have a chance to drop Pennies on the floor upon successfully hitting an enemy.
Steven	5.100.50		DMG up	Increases damage by 1.
Blood Bag	5.100.119		HP up	Grants one full Red Heart container, restores 4 Red Hearts, and increases speed by 0.3.
Bomb Bag	5.100.131		Gives bombs	Isaac is followed by a small bag that drops a Bomb, a Double Bomb, a Troll Bomb, or a Golden Bomb every 3 rooms.
Little Baggy	5.100.252		Extra pill room	Isaac can hold 2 pills at once and all cards are replaced by pills.
Mystery Sack	5.100.271		?	Spawns a familiar that drops a heart, coin, bomb, or key every 5-6 rooms.
Rune Bag	5.100.389		Rune generator	A bag that follows Isaac and drops a random rune every 5-6 rooms.
Sack of Pennies	5.100.94		Gives money	Isaac is followed by a small bag that drops a coin every 2 rooms.
Sack of Sacks	5.100.500		Gives sacks	Spawns a sack familiar that drops a sack every 5-6 rooms cleared.

Trivia

• "Bag" and "sack" items were added to the Locked Chest pool, which previously contained only "head" items.