Guillotine

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Item icon
Item altar

 
 
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Character appearance
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Item Pool Treasure Room.png Treasure Room
Added in AfterbirthGreed mode onlyItem Pool Treasure Room.png Treasure Room
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Added in Afterbirth (page 2, column 3, line 5)
Removed in Afterbirth (page 3, column 3, line 1)
 
Guillotine Defeat Isaac as JudasGuillotineGuillotine

Guillotine is an unlockable passive item.

Effects[edit | edit source]

  • Isaac's head rotates around his body and can be used to inflict contact damage similar to a Cube of Meat Cube of MeatCube of Meat Icon.pngOrbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.. Blocking tears with Isaac's head does not damage Isaac. His tears still originate from his head, so the line of fire is no longer constant while standing still.
  • +1 damage.
  • -1 tear delay (increased rate of fire)
    • Since this directly affects tear delay instead of changing the tears stat, it allows Isaac's rate of fire to go over the normal maximum rate.
    • Tear delay decreases are only noticeable when the tears stat is high.
  • The head orbital deals 7 damage per tick or 105 damage per second.

Synergies[edit | edit source]

  • Added in AfterbirthBox of Friends Box of FriendsBox of Friends Icon.png4 roomsUpon use, duplicates all of Isaac's familiars for the current room.: Adds another rotating head on each use. Each head increases damage and blocks projectiles, but does not affect tear delay. With more heads, it is easier to locate the position of the body, and Box of Friends can be used multiple times in the same room to continue gaining heads.

Interactions[edit | edit source]

  • Added in Afterbirth †Duct Tape Duct TapeDuct Tape Icon.pngStops Isaac's familiars from moving.: Causes tears to be fired from far below and to the right of Isaac. This causes tears to be out of bounds unless Isaac is standing in the top-left corner of the room.
  • Mom's Knife Mom's KnifeMom's Knife Icon.pngIsaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.: The knife fires from Isaac's body, not his head.
  • Added in AfterbirthTractor Beam Tractor BeamTractor Beam Icon.pngIsaac emits a beam from his face. Isaac's tears travel in the path of the beam.: Tears fire from Isaac's body, not his head.
  • Transcendence TranscendenceTranscendence Icon.pngGrants flight.: Makes Isaac's body invisible, leaving only a shadow where his body is. As a result, Isaac becomes very difficult to control.
  • Added in Afterbirth †Sacrificial Altar Sacrificial AltarSacrificial Altar Icon.pngOne time useUpon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.: The head is not sacrificed and no item spawns.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • If Isaac has items that visually change his hands, the effect applies to Isaac's head too. For example, when having Added in AfterbirthBursting Sack Bursting SackBursting Sack Icon.pngSpider enemies no longer target or deal contact damage to Isaac., Isaac's body and head will both holding a sack for each, while there are two extra hands added to the head.

Seeds[edit | edit source]

 PC  TR61 X22B (treasure room adjacent to spawn) (normal mode only)

 PC  V6DK 2AGO (treasure room adjacent to spawn) (normal mode only)

 PC  SPAM N693 (treasure room adjacent to spawn)

 PC  YTDT EJGK (treasure room adjacent to spawn)


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