Guppy's Tail

5.100.134

Curse Room Devil Room Red Chest Curse Room Devil Room

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Guppy's Tail is a passive item.

Effects

• Grants a 1/3 chance of replacing a pickup with a normal Chest or Locked Chest, but also a 1/3 chance to replace it with nothing at all.
• This item belongs to the Guppy set. Collecting three items from this set will transform Isaac into Guppy.

Notes

• Due to any found chests containing items while in The Chest or Dark Room, Guppy's Tail can be a good way to quickly stack up more upgrades before facing the final boss.

Synergies

• The Left Hand: Turns all chests into Red Chests, allowing you to get Red Chest items much more quickly (including Guppy items).
• Mom's Key: Increases the number of drops from chests and counteracts the increased chance to run into Locked Chests.

Trivia

• This item is used in Cat Got Your Tongue (challenge #8).

Pet Items

Cricket:

• Cricket's Body
• Cricket's Head

Guppy:

• Dead Cat
• Guppy's Collar
• Guppy's Hair Ball
• Guppy's Head
• Guppy's Paw
• Guppy's Tail

Tammy:

• Tammy's Head