From Binding of Isaac: Rebirth Wiki
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Habit is a passive item.
- When Isaac is hit, his active item gains 1 room's worth of charge.
Book of Revelations
Adds 1 soul heart, increases the chance for a Devil or Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom).: Reduced damage to some degree due to getting a 6th of a charge every hit.

Dull Razor
Hurts Isaac without depleting health, activating any items that trigger upon taking damage. + 
Schoolbag
Allows Isaac to hold two active items.: Using the Dull Razor activates the Habit, but this does not restore its own charge, only that of the item in the Schoolbag.
Placenta
Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay. +
Book of Revelations
Adds 1 soul heart, increases the chance for a Devil or Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom).: If the player is patient enough, they can be used to generate the maximum amount of Soul Hearts without losing anything.
Scapular
Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.: Allows infinite recharges of a held active item.
Yum Heart
Restores 1 whole red heart. +
9 Volt
Reduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges.: Isaac could potentially become invincible on early floors or with The Wafer, losing only half a heart per three hits taken.
Yum Heart
Restores 1 whole red heart. + 
Car Battery
Causes Isaac's activated item to activate twice on each use.: Restores two Hearts per four hits, allowing for infinite heal on early floors or with The Wafer.
- The Habit was significantly nerfed from the previous game. In the original game, it would restore half of Isaac's item's required charge rather than just one room's worth of charge. This could essentially make Isaac unkillable if it was used in conjunction with Yum Heart, The Nail, or Book of Revelations and The Wafer for The Womb and beyond.
- This item is used in Challenge #12 (When Life Gives You Lemons).