Hard mode

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Hard mode changes the gameplay compared to Normal in some ways to make it more difficult. When playing in hard mode, a small red pentagram (Hard mode only) appears on the HUD, below the consumables.

  • Rooms contain more advanced enemies and in a higher number.
  • Causes champions to spawn more often; however, they award fewer pickups.
  • You are 65% less likely to receive hearts after completing a room.
  • Only champion bosses can drop red hearts; normal bosses will not.
  • You are more likely to be cursed on each floor.
  • You are more likely to receive a harder version of a floor (e.g. Necropolis or Added in  Afterbirth Dank Depths instead of The Depths).

Unlocks for Hard Mode[edit | edit source]

Character Mom's Heart Added in  Afterbirth All Completion Marks
Isaac Lost BabyLost BabyDefeat Mom's Heart on hard mode as Isaac Buddy BabyBuddy BabyEarn all hard mode completion marks as Isaac
Magdalene Cute BabyCute BabyDefeat Mom's Heart on hard mode as Magdalene Colorful BabyColorful BabyEarn all hard mode completion marks as Magdalene
Cain Glass BabyGlass BabyDefeat Mom's Heart on hard mode as Cain Picky BabyPicky BabyEarn all hard mode completion marks as Cain
Judas Shadow BabyShadow BabyDefeat Mom's Heart on hard mode as Judas Belial BabyBelial BabyEarn all hard mode completion marks as Judas
??? Dead BabyDead BabyDefeat Mom's Heart on hard mode as ??? Hive BabyHive BabyEarn all hard mode completion marks as ???
Eve Crow BabyCrow BabyDefeat Mom's Heart on hard mode as Eve Whore BabyWhore BabyEarn all hard mode completion marks as Eve
Samson Fighting BabyFighting BabyDefeat Mom's Heart on hard mode as Samson Revenge BabyRevenge BabyEarn all hard mode completion marks as Samson
Azazel Begotten BabyBegotten BabyRemoved in Afterbirth † Defeat Mom's Heart on hard mode as Lazarus
Added in Afterbirth † Defeat Mom's Heart on hard mode as Azazel
Sucky BabySucky BabyEarn all hard mode completion marks as Azazel
Lazarus Wrapped BabyWrapped BabyRemoved in Afterbirth † Defeat Mom's Heart on hard mode as Azazel
Added in Afterbirth † Defeat Mom's Heart on hard mode as Lazarus
Dripping BabyDripping BabyEarn all hard mode completion marks as Lazarus
Eden Glitch BabyGlitch BabyDefeat Mom's Heart on hard mode as Eden Cracked BabyCracked BabyEarn all hard mode completion marks as Eden
The Lost -0- Baby-0- BabyDefeat Mom's Heart on hard mode as The Lost GodheadGodheadRemoved in Afterbirth Beat Mom's Heart, Isaac, Satan, ???, and The Lamb and complete the Boss Rush on hard mode as The Lost
Added in  Afterbirth Earn all 9 Completion Marks on hard mode as The Lost
Added in  AfterbirthLilith Goat Head BabyGoat Head BabyDefeat Mom's Heart on hard mode as Lilith Dark BabyDark BabyEarn all hard mode completion marks as Lilith
Added in  AfterbirthKeeper Super Greed BabySuper Greed BabyDefeat Mom's Heart on hard mode as Keeper Sale BabySale BabyEarn all hard mode completion marks as Keeper
Added in Afterbirth †Apollyon SmelterSmelterDefeat Mom's Heart or It Lives! on hard mode as Apollyon Apollyon BabyApollyon BabyEarn all hard mode completion marks as Apollyon
Added in Afterbirth †The Forgotten MarrowMarrowDefeat Mom's Heart or It Lives! on hard mode as The Forgotten Bone BabyBone BabyEarn all hard mode completion marks as The Forgotten

Trivia[edit | edit source]

  • Prior to update 1.03, the reduced drop-rate affected all Pickups (not just Red Hearts).
  • Godhead GodheadGodhead Icon.pngIncreases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.'s unlock requirements were extended in the Afterbirth DLC (and further extended in the Afterbirth+ DLC) due to the addition of more completion marks, but it can still be unlocked in the base game using the same method.


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