Have a Heart

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Font TeamMeat H.pngFont TeamMeat a.pngFont TeamMeat v.pngFont TeamMeat e.png   Font TeamMeat a.png   Font TeamMeat H.pngFont TeamMeat e.pngFont TeamMeat a.pngFont TeamMeat r.pngFont TeamMeat t.png
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Charm of the Vampire Charm of the Vampire
Item Pool Treasure Room.png: yes          Item Pool Shop.png: yes
Boss Mom's Heart.png / Boss It Lives.png
2 new pills 2 new pills2 new pillsComplete challenge #24
Have a Heart Defeat Mom for the 1st timeHave a HeartHave a Heart
Added in Afterbirth

Have a Heart is Challenge #25. Isaac begins the challenge with Charm of the Vampire Charm of the Vampire and 12 heart containers, but only one of them filled. The goal is to defeat Mom's Heart or It Lives.

Difficulty[edit | edit source]

Charm of the Vampire is the main way to fill Isaac's heart containers (see below for exceptions). All red heart pickups are replaced with pennies (half heart = one penny, full heart = 1+1 free penny). HP up items (e.g.: Breakfast Breakfast) give red heart containers, but do not fill HP. The Lovers Card spawns coins instead of red hearts. The 2 of Hearts card and Yum Heart Yum Heart create no effect. The Tick TickTrinket Tick icon.pngDrains 15% health of each enemy with more than 60 HP (ie. most bosses). It also restores one red heart of Isaac whenever he enters an uncleared boss room. The Tick cannot be swapped out for another trinket. will still reduce a boss' health, but will not heal upon entering the boss room. Shops sell coins instead of hearts. Slot machines, blood donation machines, the Hematemesis pill, and any of the beggars drop coins instead of hearts. Even a Super Secret Room which usually contains hearts will contain money instead. It is also impossible to recover health with Pyromaniac Pyromaniac, Placenta Placenta, or Leech Leech.

Strategy[edit | edit source]

The biggest difficulty lies in acquiring health. However, with numerous heart containers, there are several strategies to survive the challenge. First is finding a way to heal red heart damage.

  • The Full Health pill is a major boon for this challenge.
    • The Bad Trip pill can also heal fully, but only when at one heart or less.
    • When combined with these pills, the Placebo Placebo becomes very powerful. It can be purchased in shops.
  • XIX - The Sun card also heals to full health, alongside other benefits.
    • Combined with a Blank Card Blank Card, the challenge becomes trivial. This can be purchased from shops.
  • Obtaining the Habit Habit or Sharp Plug Sharp Plug from a shop allows Placebo or Blank Card to be used at will without any fear of death.
  • Rainbow poop will also give full health, but it is also very rare.
  • Beds still refill Isaacs' health.
  • Added in Afterbirth †Adrenaline Adrenaline is very helpful as Isaac will have multiple empty heart containers.

Second is getting rid of excess heart containers. Removing even one heart container will make obtaining Deals with the Devil and Angel Rooms much easier, as the open HP spot can hold soul/black hearts, providing insurance against red heart damage.

  • The Devil Room or Black Market deals not only give good items but also free up space for soul hearts. This, naturally, comes with the downside of preventing Angel Rooms from appearing.
  • The Health Down pill can clear away some extra heart containers to allow picking up Soul/Black Hearts. This can synergize with Placebo nicely.
  • Guppy's Paw Guppy's Paw is one of the more useful items for survival because it removes hard-to-fill heart containers and replaces them with soul hearts.
  • Added in Afterbirth †Potato Peeler Potato Peeler can be found in shops and easily removes excess empty heart containers for Cube of Meat Cube of Meats, Allowing you to easily get a couple of Meat Boys if desired.

A third method involves grinding enemies to replenish Isaac's health.

  • Mulligans and their variants, Sacks and other spawning enemies can provide limitless sources of enemies to fill health.
  • Getting the D7 D7 and repeatedly clearing a room filled with easy-to-kill enemies can fill Isaac's entire HP bar.
  • The Shell Game Beggar can be a useful method of spawning flies.

Because hearts turn into coins, shop purchases are easier to make.

  • Trinkets such as Bloody Penny Bloody PennyTrinket Bloody Penny icon.pngGives a 50% chance to drop a half heart when money is collected., Burnt Penny Burnt PennyTrinket Burnt Penny icon.pngGives a 50% chance to drop a bomb when money is collected., Counterfeit Penny Counterfeit PennyTrinket Counterfeit Penny icon.pngGives a 50% chance of increasing the value of every coin pickup by one., Flat Penny Flat PennyTrinket Flat Penny icon.pngGives a 50% chance of spawning a key upon collecting a penny., and Added in Afterbirth †Rotten Penny Rotten PennyTrinket Rotten Penny icon.pngSpawns a blue fly every time a coin is picked up. are beneficial, as there is a greater chance of coins dropping when Isaac finishes a room.
  • Bumbo Bumbo and Bum Friend Bum Friend are also more beneficial with the increase in coin drops.

Some other things to note:

  • If Isaac is at full health, the boss should take priority. Health lost during the battle can be replenished from unexplored rooms.
  • Avoid using Hematemesis, as it will remove all but one heart without spawning two hearts as usual.
  • If Isaac dies with a 1up! 1up!, all heart containers will be filled.
  • Judas' Shadow Judas' Shadow purges all heart containers and leaves 2 Black Hearts.
  • Mom's Locket Mom's LocketTrinket Mom's Locket icon.pngGrants half a red heart each time a key is used. Converts half red heart pickups into full red hearts. refills half a heart each time a key is used.

Reward[edit | edit source]

Mom Unlocks Mom Unlocks Mom Unlocks
The WombThe WombDefeat Mom for the 1st timeThe HarbingersThe HarbingersDefeat Mom for the 1st timeA Cube of MeatA Cube of MeatDefeat Mom for the 1st timeA HaloA HaloDefeat Mom using The BiblePuristPuristDefeat Mom for the first time XXXXXXXXLXXXXXXXXLDefeat Mom for the 1st timeSPEED!SPEED!Defeat Mom for the 1st timeHave a HeartHave a HeartDefeat Mom for the 1st timePRIDE DAY!PRIDE DAY!Defeat Mom for the 1st timeOnan's StreakOnan's StreakDefeat Mom for the 1st timeThe GuardianThe GuardianDefeat Mom for the 1st time Aprils foolAprils foolDefeat Mom for the 1st time

MainPageChallenges.png Challenges MainPageChallenges.png

1. Pitch Black 2. High Brow 3. Head Trauma 4. Darkness Falls 5. The Tank 6. Solar System 7. Suicide King 8. Cat Got Your Tongue
9. Demo Man 10. Cursed! 11. Glass Cannon 12. When Life Gives You Lemons 13. Beans! 14. It's in the Cards 15. Slow Roll 16. Computer Savvy
17. Waka Waka 18. The Host 19. The Family Man 20. Purist
21. XXXXXXXXL 22. SPEED! 23. Blue Bomber 24. PAY TO PLAY 25. Have a Heart 26. I RULE! 27. BRAINS! 28. PRIDE DAY!
29. Onan's Streak 30. The Guardian
Afterbirth †
31. Backasswards 32. Aprils Fool 33. Pokey Mans 34. Ultra Hard 35. Pong
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