Have a Heart

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Have a Heart
Added in Afterbirth
Challenge number
Isaac App.png
Full red heartEmpty red heartEmpty red heartEmpty red heartEmpty red heartEmpty red heart
Empty red heartEmpty red heartEmpty red heartEmpty red heartEmpty red heartEmpty red heart
Starting Items
Charm of the Vampire Charm of the VampireCharm of the Vampire Icon.pngHeals the character for half of a red heart for every 13 monsters killed.
Available rooms
Item Pool Treasure Room.png: yes          Item Pool Shop.png: yes
Boss Mom's Heart.png / Boss It Lives.png
Added in Afterbirth2 new pills 2 new pills2 new pillsComplete challenge #24
Unlocked by
Added in AfterbirthHave a Heart Defeat Mom for the 1st timeHave a HeartHave a Heart

Have a Heart is Challenge #25. You start off with Charm of the Vampire and 12 heart containers, but only one of them filled. Your goal is to defeat Mom's Heart or It Lives.

Difficulty[edit | edit source]

Charm of the Vampire Charm of the VampireCharm of the Vampire Icon.pngHeals the character for half of a red heart for every 13 monsters killed. is your main way to fill your heart containers (see below for exceptions). All red heart pickups are replaced with pennies (half heart = one penny, full heart = 1+1 free penny). HP up items (e.g.: Breakfast BreakfastBreakfast Icon.pngGrants Isaac one full red heart container.) give red heart containers, but do not fill HP. The Lovers Card spawns coins instead of red hearts. The 2 of Hearts card and Yum Heart Yum HeartYum Heart Icon.png4 roomsRestores 1 whole red heart. have no effect. The Tick TickTick Icon.pngDrain 15% health of each enemy with more than 60 HP (ie. most bosses). Also restores one red heart of Isaac whenever he enters an uncleared boss room. The Tick cannot be swapped out for another trinket. will still reduce a boss' health, but will not heal upon entering the boss room. Shops sell coins instead of hearts. Slot Machines, Blood Donation Machines, the Hematemesis pill, and any of the Beggars drop coins instead of hearts. Even a Super Secret Room which usually contains hearts will contain money instead. You also cannot recover health with Pyromaniac PyromaniacPyromaniac Icon.pngIsaac heals 1 heart instead of taking damage from an explosive source. Adds 5 bombs., Placenta PlacentaPlacenta Icon.pngGrants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay., or Leech LeechLeech Icon.pngSpawns a friendly familiar leech on the ground that hunts down enemies and heals you for half a heart each time it eats one..

Strategy[edit | edit source]

The biggest difficulty lies in acquiring health. However, with numerous heart containers, there are several strategies to survive the challenge. First is finding a way to fill health.

  • Obviously, the Full Health pill is a major boon for this challenge.
    • The Bad Trip pill can also heal fully, but only when at half a heart.
    • If these pills can be found, the Added in AfterbirthPlacebo PlaceboPlacebo Icon.png4 roomsWhen used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes. becomes very powerful in this challenge. It can be purchased in shops.
  • XIX - The Sun card also heals to full health, as well as providing floor plans and a Necronomicon-like effect.
    • Combined with a Blank Card Blank CardBlank Card Icon.png4 roomsHas the same effect as the card or rune currently held by Isaac., the challenge becomes trivial. This can be purchased from shops.
  • If you can also get the Habit HabitHabit Icon.pngWhen Isaac is hit, 1 point of an item's charge is filled. or Sharp Plug Sharp PlugSharp Plug Icon.pngUsing an activated item while it's not charged will charge it and Sharp Plug does 2 full heart damage to Isaac. from a shop, Placebo or Blank Card can be practically used at will without any fear of death.
  • Rainbow poop will also give full health, but it is also very rare.
  • Likewise, beds still refill your health if you can find them.

Second is getting rid of excess heart containers. Removing even one heart container will make obtaining Deals with the Devil and Angel Rooms much easier, as the open HP spot can hold Soul/Black hearts, providing insurance against red heart damage.

  • The Devil Room or Black Market deals not only give good items, but also frees up space for soul hearts. This, naturally, comes with the downside of preventing Angel Rooms.
  • The Health Down pill can clear away some of the extra heart containers to allow picking up Soul/Black Hearts. This can couple with Placebo nicely.
  • Guppy's Paw Guppy's PawGuppy's Paw Icon.pngUnlimitedRemoves one red heart container in exchange for gaining 3 Soul Hearts. is one of the more useful items for survival, because it removes hard-to-fill heart containers and replaces them with soul hearts.

A third method involves grinding enemies to fill your health.

  • Mulligans and their variants, Sacks, and other spawning enemies can provide limitless sources of enemies to fully fill health.
  • Getting the D7 D7D7 Icon.png3 roomsRestarts the current room and brings back all enemies, allowing more rewards to be acquired by completing the room. and repeatedly clearing a room filled with easy-to-kill enemies can help you fill your whole HP bar.
  • The Shell Game Beggar spawns flies when you lose.

Because hearts turn into coins, shops purchases are easier to make.

  • Trinkets such as Bloody Penny Bloody PennyBloody Penny Icon.pngGives a 50% chance to drop a half heart when money is collected., Burnt Penny Burnt PennyBurnt Penny Icon.pngGives a 50% chance to drop a bomb when money is collected., Counterfeit Penny Counterfeit PennyCounterfeit Penny Icon.pngGives a 50% chance of increasing the value of every coin pickup by one., Flat Penny Flat PennyFlat Penny Icon.pngGives a 50% chance of spawning a key upon collecting a penny., and Added in Afterbirth †Rotten Penny Rotten PennyRotten Penny Icon.pngSpawns a blue fly every time a coin is picked up. are beneficial, as there is a greater chance of coins dropping when Isaac finishes a room.
  • Bumbo BumboBumbo Icon.pngSpawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage. and Bum Friend Bum FriendBum Friend Icon.pngA portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickup after collecting a coin. Does not spawn collectibles. also are better with the increase in coin drops.

Some other things to note:

  • If you manage to get full health, the boss should take priority. Health lost during the battle can be replenished from unexplored rooms.
  • Avoid using Hematemesis, as it will remove all but one heart without spawning two hearts as usual.
  • If you die with 1up! 1up!1up! Icon.pngGives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1up!., all heart containers will be filled.
  • Judas' Shadow Judas' ShadowJudas' Shadow Icon.pngAdds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts. purges your heart containers and leaves 2 Black Hearts.
  • Mom's Locket Mom's LocketMom's Locket Icon.pngGrants half a red heart each time a key is used. Converts half red heart pickups into full red hearts. refills half a heart each time a key is used.

Reward[edit | edit source]

The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
MainPageAchievements.png Achievements MainPageAttributes.png Attributes MainPageBosses.png Bosses TarotCard.png Cards and Runes MainPageChallenges.png Challenges MainPageChapters.png Chapters
Isaac App.png Characters MainPageBabies.png Co-op MainPageItems Small.png Items Item Pools Item Pools MainPageMonsters.png Monsters MainPageObjects.png Objects
Red heart.png Pickups BlueBlue.png Pills MainPageRooms.png Rooms MainPageSeeds2.png Seeds Guppy App.png Transformations The Left Hand Icon.png Trinkets