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High Brow

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Font TeamMeat H.pngFont TeamMeat i.pngFont TeamMeat g.pngFont TeamMeat h.png   Font TeamMeat B.pngFont TeamMeat r.pngFont TeamMeat o.pngFont TeamMeat w.png
IsaacIsaac
Full red heartFull red heartFull red heart
Table dividing line 1.png
 
 
Number One Number OneNumber One Icon.png+1.5 tears, -17.62 range
E Coli E ColiE Coli Icon.pngGives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.
Butt Bombs Butt BombsButt Bombs Icon.pngGives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies.
Flush! Flush!Flush! Icon.png6 roomsChanges all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie.

Petrified Poop Petrified PoopPetrified Poop Icon.pngGreatly increases the chances of a pickup dropping when destroying poop.
 
Item Pool Treasure Room.png: no          Item Pool Shop.png: yes
Boss Mom.png
Rune of Jera Rune of JeraRune of JeraComplete challenge #2

High Brow is challenge #2. This challenge starts you with Number One Number OneNumber One Icon.png+1.5 tears, -17.62 range, E Coli E ColiE Coli Icon.pngGives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop., Butt Bombs Butt BombsButt Bombs Icon.pngGives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies., Flush! Flush!Flush! Icon.png6 roomsChanges all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie., and Petrified Poop Petrified PoopPetrified Poop Icon.pngGreatly increases the chances of a pickup dropping when destroying poop.. Your goal is to defeat Mom. This challenge is unlocked by default.

Difficulty[edit | edit source]

Starting with Number One Number OneNumber One Icon.png+1.5 tears, -17.62 range gives you a much shorter range for your tears. You'll need to get closer to your enemies to defeat them.

Strategy[edit | edit source]

  • Flush! Flush!Flush! Icon.png6 roomsChanges all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie. can be powerful when dealing with a large number of enemies, such as in a 2x2 room. Turning all the enemies into poop can save you quite a bit of time, and Petrified Poop Petrified PoopPetrified Poop Icon.pngGreatly increases the chances of a pickup dropping when destroying poop. can then increase your chances of valuable pickups.
  • E Coli E ColiE Coli Icon.pngGives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop. can turn enemies into poop. Given the short range because of Number One Number OneNumber One Icon.png+1.5 tears, -17.62 range, you will have an increased chance of contact damage. Try to touch every enemy that doesn't damage you (Black Flies, Mulligan, Hosts etc). They will still be transformed into poop. This works well with Petrified Poop Petrified PoopPetrified Poop Icon.pngGreatly increases the chances of a pickup dropping when destroying poop..
    • This also works well with Skatole SkatoleSkatole Icon.pngAll types of fly except Boom Fly and Red Boom Fly become passive and slowly move towards Isaac. Does not prevent contact damage.. Attack flies are instantly transformed into harmless black flies that can be touched and transformed into poop.
  • Butt Bombs Butt BombsButt Bombs Icon.pngGives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies. gives you 5 extra bombs to start with, which can make getting some items or secret rooms easier to find in the first 2 levels.
  • Because of Number One Number OneNumber One Icon.png+1.5 tears, -17.62 range's synergy with Brimstone BrimstoneBrimstone Icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period., it is highly recommended if the deal is available.
  • Slow but potentially useful synergy with Petrified Poop if you find Mysterious Candy. Good if you find yourself strapped for coins, especially early on.

Unlockable achievements[edit | edit source]


MainPageChallenges.png Challenges MainPageChallenges.png

Rebirth
1. Pitch Black 2. High Brow 3. Head Trauma 4. Darkness Falls 5. The Tank 6. Solar System 7. Suicide King 8. Cat Got Your Tongue
9. Demo Man 10. Cursed! 11. Glass Cannon 12. When Life Gives You Lemons 13. Beans! 14. It's in the Cards 15. Slow Roll 16. Computer Savvy
17. Waka Waka 18. The Host 19. The Family Man 20. Purist
Afterbirth
21. XXXXXXXXL 22. SPEED! 23. Blue Bomber 24. PAY TO PLAY 25. Have a Heart 26. I RULE! 27. BRAINS! 28. PRIDE DAY!
29. Onan's Streak 30. The Guardian
Afterbirth †
31. Backasswards 32. Aprils Fool 33. Pokey Mans 34. Ultra Hard 35. Pong
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets