Immaculate Conception

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Font TeamMeat I.pngFont TeamMeat m.pngFont TeamMeat m.pngFont TeamMeat a.pngFont TeamMeat c.pngFont TeamMeat u.pngFont TeamMeat l.pngFont TeamMeat a.pngFont TeamMeat t.pngFont TeamMeat e.png   Font TeamMeat C.pngFont TeamMeat o.pngFont TeamMeat n.pngFont TeamMeat c.pngFont TeamMeat e.pngFont TeamMeat p.pngFont TeamMeat t.pngFont TeamMeat i.pngFont TeamMeat o.pngFont TeamMeat n.png
Item icon
Item altar
 
 
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5.100.413
 
Character appearance
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Angel Room Angel Room
Greed mode only Angel Room Angel Room
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Added in Afterbirth †(page 4, column 8, row 3)
Removed in Afterbirth †(page 4, column 8, row 3)
 
Immaculate Conception Complete the Boss Rush as LilithImmaculate ConceptionImmaculate Conception
Added in Afterbirth

Immaculate Conception is an unlockable passive item added in Afterbirth.

Effect[edit | edit source]

  • Upon picking up enough heart pickups, Isaac gains a permanent angelic familiar and generates a soul heart drop. Possible familiars include:
  • All five familiars will spawn in a random order, each after collecting 15 hearts.
  • After all familiars have been spawned, a soul heart will still drop every 15 hearts collected.

Notes[edit | edit source]

  • All types of hearts except gold hearts and blended hearts count.
    • The amount healed by the heart does not matter, and as such half hearts are the most effective way to activate the item.
  • Items that directly add health such as Yum Heart Yum Heart, Book of Revelations Book of Revelations, Satanic Bible Satanic Bible, and The Nail The Nail do not count towards spawning a familiar.
  • Only one of each type of familiar can be spawned.
  • This item is the angelic counterpart to Cambion Conception Cambion Conception.
  • The Lost can pick up soul hearts and black hearts despite having no health and thus can activate Immaculate Conception.
  • Keeper cannot encounter hearts and thus the item is useless for him.

Interactions[edit | edit source]

  • The Jar The Jar: Hearts collected in the jar do not count towards activation.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Immaculate Conception refers to the Catholic teaching that the conception of the Virgin Mary was free from original sin.


Lilith Unlocks Lilith Unlocks Lilith Unlocks
IncubusIncubusDefeat Hush as LilithBox of FriendsBox of FriendsDefeat Ultra Greed as LilithBig BabyBig BabyDefeat Mega Satan as LilithRune BagRune BagDefeat Isaac as LilithCambion ConceptionCambion ConceptionDefeat ??? as LilithSerpent's KissSerpent's KissDefeat Satan as LilithSuccubusSuccubusDefeat The Lamb as LilithImmaculate ConceptionImmaculate ConceptionComplete the Boss Rush as LilithGoat Head BabyGoat Head BabyDefeat Mom's Heart on hard mode as LilithDark BabyDark BabyEarn all hard mode completion marks as Lilith EuthanasiaEuthanasiaDefeat Delirium as LilithDualityDualityDefeat Ultra Greedier as Lilith
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