Immaculate Conception

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Item icon
Item altar
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Character appearance
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Added in Afterbirth †(page 4, column 8, row 3)
Removed in Afterbirth †(page 4, column 8, row 3)

Immaculate Conception Complete the Boss Rush as Lilith
Added in Afterbirth

Immaculate Conception is an unlockable passive item added in The Binding of Isaac: Afterbirth.

Effects[edit | edit source]

  • Upon picking up enough heart pickups, Isaac gains a permanent angelic familiar and generates a Soul Heart drop. Possible familiars include:
  • All five familiars will spawn in a random order, each after collecting 15 hearts.
  • After all familiars have been spawned, a Soul Heart will still drop every 15 hearts collected.

Notes[edit | edit source]

  • All types of hearts except Gold Hearts and Blended Hearts count.
    • The amount healed by the heart does not matter, and as such half hearts are the most effective way to activate the item.
  • Items that directly add health such as Yum Heart Yum Heart, Book of Revelations Book of Revelations, Satanic Bible Satanic Bible, and The Nail The Nail do not count towards spawning a familiar.
  • Only one of each type of familiar can be spawned.
  • This item is the angelic counterpart to Cambion Conception Cambion Conception.
  • The Lost can pick up Soul Hearts and Black Hearts despite having no health and thus can activate Immaculate Conception.
  • Keeper cannot encounter hearts and thus the item is useless for him.

Interactions[edit | edit source]

  • The Jar The Jar: Hearts collected in the jar do not count towards activation.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Immaculate Conception refers to the Catholic teaching that the conception of the Virgin Mary was free from original sin.

Lilith Unlocks Lilith Unlocks Lilith Unlocks
IncubusBox of FriendsBig BabyRune BagCambion ConceptionSerpent's KissSuccubusImmaculate ConceptionGoat Head BabyDark Baby EuthanasiaDuality
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