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Font TeamMeat I.pngFont TeamMeat n.pngFont TeamMeat f.pngFont TeamMeat e.pngFont TeamMeat s.pngFont TeamMeat t.pngFont TeamMeat a.pngFont TeamMeat t.pngFont TeamMeat i.pngFont TeamMeat o.pngFont TeamMeat n.png
Removed in Afterbirth † Item icon
Added in Afterbirth † Item icon
Item altar
Table dividing line 1.png


Character appearance
Table dividing line 2.png
Table dividing line 3.png

Added in Afterbirth(page 2, column 5, row 2)
Removed in Afterbirth(page 2, column 5, row 5)

Infestation is a passive item.

Effects[edit | edit source]

  • 1-3 Blue Flies randomly spawn whenever Isaac takes damage.
  • This item belongs to the Beelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.

Interactions[edit | edit source]

  • Added in Afterbirth †Fish Tail Fish Tail: Doubles number of flies spawned.
  • Hive Mind Hive Mind: Flies are bigger and deal double damage.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

 PC  Normal mode only 8H3N AE8H (Treasure Room adjacent to spawn)

 PC  CW0L S1LN (Treasure Room in one room above the spawn)

 PC  33QM WGYC (Treasure Room in one room above the spawn)

 PS4  QZ8P 4BQF (Treasure Room adjacent to spawn)

 PS4  2VP2 JVWH (Treasure Room two rooms above spawn)

 PS4  SAPZ YHX0 (First floor treasure room)

 3DS  LBXS W367 (Treasure Room adjacent to spawn)

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