Items are an integral part of game-play in The Binding of Isaac: Rebirth. They modify Isaac's attributes, grant or modify tear effects, and much more.
Items are classified into a number of distinct types and groups. Some items are passive, which add an effect permanently to Isaac, while others only activate when used. The original Binding of Isaac had 196 items. Rebirth has as a total of 341 items. Afterbirth added 95 new items, for a total of 436 items. Afterbirth † has added 68 new items, for a total of 504 items. Only 13 items are considered special.
Similar to items are cards and runes, pills, and trinkets.
For a list of which items can potentially appear in a given Special Room, see Item Pool.
For the grids of items that appear in the stats menu, see Collection Page.
Activated Collectibles
Passive Collectibles
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